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1CNN
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OMEGA-CONOTOXIN MVIIC FROM CONUS MAGUS
分子名称: OMEGA-CONOTOXIN MVIIC
著者Nielsen, K.J, Adams, D, Thomas, L, Bond, T, Alewood, P.F, Craik, D.J, Lewis, R.J.
登録日1999-05-20
公開日2000-05-31
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure-activity relationships of omega-conotoxins MVIIA, MVIIC and 14 loop splice hybrids at N and P/Q-type calcium channels.
J.Mol.Biol., 289, 1999
1A0M
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BU of 1a0m by Molmil
1.1 ANGSTROM CRYSTAL STRUCTURE OF A-CONOTOXIN [TYR15]-EPI
分子名称: ALPHA-CONOTOXIN [TYR15]-EPI
著者Hu, S.-H, Loughnan, M, Miller, R, Weeks, C.M, Blessing, R.H, Alewood, P.F, Lewis, R.J, Martin, J.L.
登録日1997-12-03
公開日1999-01-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献The 1.1 A resolution crystal structure of [Tyr15]EpI, a novel alpha-conotoxin from Conus episcopatus, solved by direct methods.
Biochemistry, 37, 1998
1AV3
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POTASSIUM CHANNEL BLOCKER KAPPA CONOTOXIN PVIIA FROM C. PURPURASCENS, NMR, 20 STRUCTURES
分子名称: Kappa-conotoxin PVIIA
著者Scanlon, M.J, Naranjo, D, Thomas, L, Alewood, P.F, Lewis, R.J, Craik, D.J.
登録日1997-09-24
公開日1998-10-14
最終更新日2020-12-16
実験手法SOLUTION NMR
主引用文献Solution structure and proposed binding mechanism of a novel potassium channel toxin kappa-conotoxin PVIIA.
Structure, 5, 1997
9BFL
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Solution structure of the scorpion toxin omega-Buthitoxin-Hf1a
分子名称: Buthitoxin-Hf1a
著者Rosengren, K.J, Payne, C.D.
登録日2024-04-18
公開日2024-06-05
実験手法SOLUTION NMR
主引用文献Novel Scorpion Toxin omega-Buthitoxin-Hf1a Selectively Inhibits Calcium Influx via Ca V 3.3 and Ca V 3.2 and Alleviates Allodynia in a Mouse Model of Acute Postsurgical Pain.
Int J Mol Sci, 25, 2024
2FQC
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Solution structure of conotoxin pl14a
分子名称: Alpha/kappa-conotoxin pl14a
著者Craik, D.J, Daly, N.L.
登録日2006-01-18
公開日2006-07-18
最終更新日2020-06-24
実験手法SOLUTION NMR
主引用文献A Novel Conotoxin Inhibitor of Kv1.6 Channel and nAChR Subtypes Defines a New Superfamily of Conotoxins
Biochemistry, 45, 2006
4RUD
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Crystal structure of a three finger toxin
分子名称: Three-finger toxin 3b, ZINC ION
著者Jobichen, C, Sivaraman, J.
登録日2014-11-18
公開日2016-05-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Fulditoxin, representing a new class of dimeric snake toxins, defines novel pharmacology at nicotinic ACh receptors.
Br.J.Pharmacol., 177, 2020
7LVN
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Solution structure of tarantula toxin omega-Avsp1a
分子名称: Omega-Avsp1a
著者Chin, Y.K.Y, Herzig, V, King, G.F.
登録日2021-02-26
公開日2022-03-02
最終更新日2023-10-11
実験手法SOLUTION NMR
主引用文献The Tarantula Toxin omega-Avsp1a Specifically Inhibits Human Ca V 3.1 and Ca V 3.3 via the Extracellular S3-S4 Loop of the Domain 1 Voltage-Sensor.
Biomedicines, 10, 2022
5T90
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Structural mechanisms for alpha-conotoxin selectivity at the human alpha3beta4 nicotinic acetylcholine receptor
分子名称: Acetylcholine-binding protein, LsIA
著者Abraham, N, Healy, M, Ragnarsson, L, Brust, A, Alewood, P, Lewis, R.
登録日2016-09-08
公開日2017-04-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural mechanisms for alpha-conotoxin activity at the human alpha 3 beta 4 nicotinic acetylcholine receptor.
Sci Rep, 7, 2017
6AZA
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NMR structure of sea anemone toxin Kappa-actitoxin-Ate1a
分子名称: ARG-CYS-LYS-THR-CYS-SER-LYS-GLY-ARG-CYS-ARG-PRO-LYS-PRO-ASN-CYS-GLY-NH2
著者Chin, Y.K.-Y, Madio, B, King, G.F, Undheim, E.A.B.
登録日2017-09-10
公開日2018-09-12
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold.
Cell. Mol. Life Sci., 75, 2018
6CEI
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Solution NMR Structure of Conotoxin GXIA from Conus geographus
分子名称: GXIA
著者Armstrong, D.A, Rosengren, K.J.
登録日2018-02-12
公開日2018-03-07
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Chemical Synthesis and NMR Solution Structure of Conotoxin GXIA from Conus geographus .
Mar Drugs, 19, 2021
6CEG
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Solution NMR structure of the omega conotoxin MoVIB from Conus moncuri
分子名称: conotoxin MoVIB
著者Rosengren, K.J.
登録日2018-02-11
公開日2018-03-07
最終更新日2020-01-01
実験手法SOLUTION NMR
主引用文献Novel analgesic omega-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides.
Sci Rep, 8, 2018
1NE5
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Solution Structure of HERG Specific Scorpion Toxin CnErg1
分子名称: ergtoxin
著者Torres, A.M, Paramjit, B, Alewood, P, Kuchel, P.W, Vandenberg, J.I.
登録日2002-12-10
公開日2003-04-01
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of CnErg1 (Ergtoxin), a HERG specific scorpion toxin
FEBS Lett., 539, 2003
2BC8
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[Sec2,3,8,12]-ImI
分子名称: Alpha-conotoxin ImI
著者Armishaw, C.J.
登録日2005-10-18
公開日2006-03-14
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献{alpha}-Selenoconotoxins, a New Class of Potent {alpha}7 Neuronal Nicotinic Receptor Antagonists.
J.Biol.Chem., 281, 2006
2BC7
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Solution structure of [Sec2,8]-ImI
分子名称: Alpha-conotoxin ImI
著者Armishaw, C.J.
登録日2005-10-18
公開日2006-03-14
最終更新日2014-08-06
実験手法SOLUTION NMR
主引用文献{alpha}-Selenoconotoxins, a New Class of Potent {alpha}7 Neuronal Nicotinic Receptor Antagonists.
J.Biol.Chem., 281, 2006
2MUB
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Solution structure of the analgesic sea anemone peptide APETx2
分子名称: Toxin APETx2
著者Mobli, M, King, G.F, Rosengren, K.J, Jensen, J.E.
登録日2014-09-07
公開日2014-12-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping Pharmacophores.
J.Med.Chem., 57, 2014
1G9P
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SOLUTION STRUCTURE OF THE INSECTICIDAL CALCIUM CHANNEL BLOCKER OMEGA-ATRACOTOXIN-HV2A
分子名称: OMEGA-ATRACOTOXIN-HV2A
著者Wang, X.-H, King, G.F.
登録日2000-11-27
公開日2002-02-21
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Discovery and structure of a potent and highly specific blocker of insect calcium channels.
J.Biol.Chem., 276, 2001
1HP3
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C-TERMINAL TRUNCATION OF OMEGA-ATRACOTOXIN-HV2A (CT-HV2A)
分子名称: OMEGA-ATRACOTOXIN-HV2A
著者Wang, X.-H, King, G.F.
登録日2000-12-12
公開日2002-12-11
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Discovery and structure of a potent and highly specific blocker of insect calcium channels
J.Biol.Chem., 276, 2001
5WLX
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Solution structure of kappa-theraphotoxin-Aa1a
分子名称: Kappa-theraphotoxin-Aa1a
著者Chin, Y.K.Y, Ma, L, King, G.F.
登録日2017-07-28
公開日2018-08-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target.
Biochem. Pharmacol., 158, 2018
5T4R
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BU of 5t4r by Molmil
NMR solution structure of the Nav1.7 selective spider venom-derived peptide Pn3a
分子名称: Mu-theraphotoxin-Pn3a
著者Rosengren, K.J, Armstrong, D.A, Vetter, I.
登録日2016-08-30
公開日2017-09-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Pharmacological characterisation of the highly Na V 1.7 selective spider venom peptide Pn3a.
Sci Rep, 7, 2017
1A3P
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ROLE OF THE 6-20 DISULFIDE BRIDGE IN THE STRUCTURE AND ACTIVITY OF EPIDERMAL GROWTH FACTOR, NMR, 20 STRUCTURES
分子名称: EPIDERMAL GROWTH FACTOR
著者Barnham, K, Torres, A, Alewood, D, Alewood, P, Domagala, T, Nice, E, Norton, R.
登録日1998-01-22
公開日1998-07-29
最終更新日2018-03-14
実験手法SOLUTION NMR
主引用文献Role of the 6-20 disulfide bridge in the structure and activity of epidermal growth factor.
Protein Sci., 7, 1998
2KRA
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BU of 2kra by Molmil
Solution structure of Bv8
分子名称: Prokineticin Bv8
著者Daly, N.L, Craik, D.J, Mobli, M.
登録日2009-12-14
公開日2010-08-11
最終更新日2014-04-23
実験手法SOLUTION NMR
主引用文献Chemical synthesis and structure of the prokineticin Bv8
CHEMBIOCHEM, 11, 2010
1ONU
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BU of 1onu by Molmil
NMDA RECEPTOR ANTAGONIST, CONANTOKIN-G, NMR, 17 STRUCTURES
分子名称: CONANTOKIN-G
著者Skjaerbaek, N, Nielsen, K.J, Lewis, R.J, Alewood, P.F, Craik, D.J.
登録日1996-08-27
公開日1997-09-04
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Determination of the solution structures of conantokin-G and conantokin-T by CD and NMR spectroscopy.
J.Biol.Chem., 272, 1997
1ONT
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NMDA RECEPTOR ANTAGONIST, CONANTOKIN-T, NMR, 17 STRUCTURES
分子名称: CONANTOKIN-T
著者Skjaerbaek, N, Nielsen, K.J, Lewis, R.J, Alewood, P.F, Craik, D.J.
登録日1996-08-27
公開日1997-09-04
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Determination of the solution structures of conantokin-G and conantokin-T by CD and NMR spectroscopy.
J.Biol.Chem., 272, 1997
2M9L
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Solution structure of protoxin-1
分子名称: Beta-theraphotoxin-Tp1a
著者Daly, N.
登録日2013-06-13
公開日2014-04-30
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1-S4 gating domain.
Curr.Biol., 24, 2014
2N7F
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NMR solution structure of muO-conotoxin MfVIA
分子名称: muO-conotoxin MfVIA
著者Schroeder, C.I, Mobli, M.
登録日2015-09-09
公開日2016-04-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Development of a mu O-Conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Sodium Channel NaV1.8.
J.Biol.Chem., 291, 2016

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