1I9S
| CRYSTAL STRUCTURE OF THE RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME | 分子名称: | CACODYLATE ION, ISOPROPYL ALCOHOL, MAGNESIUM ION, ... | 著者 | Changela, A, Ho, C.K, Martins, A, Shuman, S, Mondragon, A. | 登録日 | 2001-03-20 | 公開日 | 2001-05-23 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme. EMBO J., 20, 2001
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1I9T
| CRYSTAL STRUCTURE OF THE OXIDIZED RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME | 分子名称: | CACODYLATE ION, ISOPROPYL ALCOHOL, MAGNESIUM ION, ... | 著者 | Changela, A, Ho, C.K, Martins, A, Shuman, S, Mondragon, A. | 登録日 | 2001-03-20 | 公開日 | 2001-05-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme. EMBO J., 20, 2001
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5DTL
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5DTX
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1VS0
| Crystal Structure of the Ligase Domain from M. tuberculosis LigD at 2.4A | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Putative DNA ligase-like protein Rv0938/MT0965, ... | 著者 | Akey, D, Martins, A, Aniukwu, J, Glickman, M.S, Shuman, S, Berger, J.M, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2006-01-27 | 公開日 | 2006-02-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structure and Nonhomologous End-joining Function of the Ligase Component of Mycobacterium DNA Ligase D. J.Biol.Chem., 281, 2006
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8BA0
| Drosophila melanogaster complex I in the Twisted state (Dm2) | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ... | 著者 | Agip, A.N.A, Chung, I, Sanchez-Martinez, A, Whitworth, A.J, Hirst, J. | 登録日 | 2022-10-10 | 公開日 | 2023-01-18 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | 主引用文献 | Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster. Elife, 12, 2023
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8B9Z
| Drosophila melanogaster complex I in the Active state (Dm1) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Agip, A.A, Chung, I, Sanchez-Martinez, A, Whitworth, A.J, Hirst, J. | 登録日 | 2022-10-10 | 公開日 | 2023-01-18 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster. Elife, 12, 2023
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6L8U
| Crystal structure of human BCDIN3D in complex with SAH | 分子名称: | RNA 5'-monophosphate methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Liu, Y, Martinez, A, Yamashita, S, Tomita, K. | 登録日 | 2019-11-07 | 公開日 | 2019-12-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.925 Å) | 主引用文献 | Crystal structure of human cytoplasmic tRNAHis-specific 5'-monomethylphosphate capping enzyme. Nucleic Acids Res., 48, 2020
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7OPT
| Crystal structure of Trypanosoma cruzi peroxidase | 分子名称: | Ascorbate peroxidase, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Freeman, S.L, Kwon, H, Skafar, V, Fielding, A.J, Martinez, A, Piacenza, L, Radi, R, Raven, E.L. | 登録日 | 2021-06-01 | 公開日 | 2022-06-08 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Crystal structure of Trypanosoma cruzi heme peroxidase and characterization of its substrate specificity and compound I intermediate. J.Biol.Chem., 298, 2022
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7OQR
| Crystal structure of Trypanosoma cruzi peroxidase | 分子名称: | ACETATE ION, Ascorbate peroxidase, GLYCEROL, ... | 著者 | Freeman, S.L, Kwon, H, Skafar, V, Fielding, A.J, Martinez, A, Piacenza, L, Radi, R, Raven, E.L. | 登録日 | 2021-06-04 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Crystal structure of Trypanosoma cruzi heme peroxidase and characterization of its substrate specificity and compound I intermediate. J.Biol.Chem., 298, 2022
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7AAJ
| Human porphobilinogen deaminase in complex with cofactor | 分子名称: | 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, GLYCEROL, Porphobilinogen deaminase | 著者 | Kallio, J.P, Bustad, H.J, Martinez, A. | 登録日 | 2020-09-04 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Characterization of porphobilinogen deaminase mutants reveals that arginine-173 is crucial for polypyrrole elongation mechanism. Iscience, 24, 2021
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7AAK
| Human porphobilinogen deaminase R173W mutant crystallized in the ES2 intermediate state | 分子名称: | 3-[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-3-(3-hydroxy-3-oxopropyl)-5-methyl-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-1~{H}-pyrrol-3-yl]propanoic acid, GLYCEROL, Porphobilinogen deaminase | 著者 | Kallio, J.P, Bustad, H.J, Martinez, A. | 登録日 | 2020-09-04 | 公開日 | 2021-02-17 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Characterization of porphobilinogen deaminase mutants reveals that arginine-173 is crucial for polypyrrole elongation mechanism. Iscience, 24, 2021
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1TDW
| Crystal structure of double truncated human phenylalanine hydroxylase BH4-responsive PKU mutant A313T. | 分子名称: | FE (III) ION, Phenylalanine-4-hydroxylase | 著者 | Erlandsen, H, Pey, A.L, Gamez, A, Perez, B, Desviat, L.R, Aguado, C, Koch, R, Surendran, S, Tyring, S, Matalon, R, Scriver, C.R, Ugarte, M, Martinez, A, Stevens, R.C. | 登録日 | 2004-05-24 | 公開日 | 2004-11-30 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations. Proc.Natl.Acad.Sci.Usa, 101, 2004
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1TG2
| Crystal structure of phenylalanine hydroxylase A313T mutant with 7,8-dihydrobiopterin bound | 分子名称: | 2-AMINO-6-(1,2-DIHYDROXY-PROPYL)-7,8-DIHYDRO-6H-PTERIDIN-4-ONE, FE (III) ION, Phenylalanine-4-hydroxylase | 著者 | Erlandsen, H, Pey, A.L, Gamez, A, Perez, B, Desviat, L.R, Aguado, C, Koch, R, Surendran, S, Tyring, S, Matalon, R, Scriver, C.R, Ugarte, M, Martinez, A, Stevens, R.C. | 登録日 | 2004-05-28 | 公開日 | 2004-11-30 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations. Proc.Natl.Acad.Sci.Usa, 101, 2004
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7PIM
| Partial structure of tyrosine hydroxylase lacking the first 35 residues in complex with dopamine. | 分子名称: | FE (III) ION, L-DOPAMINE, Regulatory domain alpha-helix, ... | 著者 | Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Valpuesta, J.M, Martinez, A, Flydal, M.I. | 登録日 | 2021-08-20 | 公開日 | 2021-12-22 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation. Nat Commun, 13, 2022
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8PND
| The ES3 intermediate of hydroxymethylbilane synthase R167Q variant | 分子名称: | 1,2-ETHANEDIOL, 3-[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-3-(3-hydroxy-3-oxopropyl)-5-methyl-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-1~{H}-pyrrol-3-yl]propanoic acid, GLYCEROL, ... | 著者 | Saeter, M.C, Bustad, H.J, Laitaoja, M, Janis, J, Martinez, A, Aarsand, A.K, Kallio, J.P. | 登録日 | 2023-06-30 | 公開日 | 2023-11-01 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | One ring closer to a closure: the crystal structure of the ES 3 hydroxymethylbilane synthase intermediate. Febs J., 291, 2024
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6ZVP
| Atomic model of the EM-based structure of the full-length tyrosine hydroxylase in complex with dopamine (residues 40-497) in which the regulatory domain (residues 40-165) has been included only with the backbone atoms | 分子名称: | FE (III) ION, L-DOPAMINE, Tyrosine 3-monooxygenase | 著者 | Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Valpuesta, J.M, Martinez, A, Flydal, M.I. | 登録日 | 2020-07-27 | 公開日 | 2021-11-17 | 最終更新日 | 2022-02-02 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation. Nat Commun, 13, 2022
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6ZN2
| Partial structure of tyrosine hydroxylase in complex with dopamine showing the catalytic domain and an alpha-helix from the regulatory domain involved in dopamine binding. | 分子名称: | FE (III) ION, L-DOPAMINE, SER-LEU-ILE-GLU-ASP-ALA-ARG-LYS-GLU-ARG-GLU-ALA-ALA-VAL-ALA-ALA-ALA-ALA, ... | 著者 | Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Valpuesta, J.M, Martinez, A, Flydal, M.I. | 登録日 | 2020-07-06 | 公開日 | 2021-12-08 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation. Nat Commun, 13, 2022
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6ZZU
| Partial structure of the substrate-free tyrosine hydroxylase (apo-TH). | 分子名称: | FE (III) ION, Tyrosine 3-monooxygenase | 著者 | Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Valpuesta, J.M, Martinez, A, Flydal, M.I. | 登録日 | 2020-08-05 | 公開日 | 2021-11-17 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation. Nat Commun, 13, 2022
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7A2G
| Full-length structure of the substrate-free tyrosine hydroxylase (apo-TH). | 分子名称: | FE (III) ION, Tyrosine 3-monooxygenase | 著者 | Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Flydal, M.I, Martinez, A, Valpuesta, J.M. | 登録日 | 2020-08-17 | 公開日 | 2021-12-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation. Nat Commun, 13, 2022
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2V28
| Apo structure of the cold active phenylalanine hydroxylase from Colwellia psychrerythraea 34H | 分子名称: | PHENYLALANINE-4-HYDROXYLASE, SULFATE ION | 著者 | Leiros, H.-K.S, Pey, A.L, Innselset, M, Moe, E, Leiros, I, Steen, I.H, Martinez, A. | 登録日 | 2007-06-04 | 公開日 | 2007-06-19 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure of Phenylalanine Hydroxylase from Colwellia Psychrerythraea 34H, a Monomeric Cold Active Enzyme with Local Flexibility Around the Active Site and High Overall Stability. J.Biol.Chem., 282, 2007
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2V27
| Structure of the cold active phenylalanine hydroxylase from Colwellia psychrerythraea 34H | 分子名称: | FE (III) ION, PHENYLALANINE HYDROXYLASE, SULFATE ION | 著者 | Leiros, H.-K.S, Pey, A.L, Innselset, M, Moe, E, Leiros, I, Steen, I.H, Martinez, A. | 登録日 | 2007-06-03 | 公開日 | 2007-06-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of Phenylalanine Hydroxylase from Colwellia Psychrerythraea 34H, a Monomeric Cold Active Enzyme with Local Flexibility Around the Active Site and High Overall Stability. J.Biol.Chem., 282, 2007
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2UXR
| Complex with isocitrate and the protein isocitrate dehydrogenase from the psychrophilic bacterium Desulfotalea psychrophila | 分子名称: | GLYCEROL, ISOCITRATE DEHYDROGENASE, ISOCITRIC ACID, ... | 著者 | Fedoy, A.-E, Yang, N, Martinez, A, Leiros, H.-K.S, Steen, I.H. | 登録日 | 2007-03-29 | 公開日 | 2008-02-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and Functional Properties of Isocitrate Dehydrogenase from the Psychrophilic Bacterium Desulfotalea Psychrophila Reveal a Cold -Active Enzyme with an Unusual High Thermal J.Mol.Biol., 372, 2007
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2UXQ
| Isocitrate dehydrogenase from the psychrophilic bacterium Desulfotalea psychrophila: biochemical properties and crystal structure analysis | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, ISOCITRATE DEHYDROGENASE NATIVE, ... | 著者 | Fedoy, A.-E, Yang, N, Martinez, A, Leiros, H.-K.S, Steen, I.H. | 登録日 | 2007-03-29 | 公開日 | 2008-02-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural and Functional Properties of Isocitrate Dehydrogenase from the Psychrophilic Bacterium Desulfotalea Psychrophila Reveal a Cold -Active Enzyme with an Unusual High Thermal J.Mol.Biol., 372, 2007
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7KM3
| Dodecameric Structure of the Chlamydia trachomatis Flavin Prenyltransferase UbiX Ortholog CT220 with FMN and DMAP | 分子名称: | Dimethylallyl monophosphate, FLAVIN MONONUCLEOTIDE, Flavin prenyltransferase UbiX | 著者 | Nguyen, T, Nicely, N.I, Belaia-Martiniouk, A, Dunne, A.P, McCafferty, D.G. | 登録日 | 2020-11-02 | 公開日 | 2021-11-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Functional and structural validation of CT220 as the UbiX-like flavin prenyltransferase from Chlamydial menaquinone biosynthesis To be published
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