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3CTO
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BU of 3cto by Molmil
Crystal Structure of M. tuberculosis YefM antitoxin
分子名称: SULFATE ION, Uncharacterized protein Rv3357/MT3465
著者Kumar, P, Issac, B, Dodson, E.J, Turkenberg, J.P, Mande, S.C.
登録日2008-04-14
公開日2008-12-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of Mycobacterium tuberculosis YefM antitoxin reveals that it is not an intrinsically unstructured protein
J.Mol.Biol., 383, 2008
4R7E
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BU of 4r7e by Molmil
Structure of Bre1 RING domain
分子名称: E3 ubiquitin-protein ligase BRE1, ZINC ION
著者Kumar, P, Wolberger, C.
登録日2014-08-27
公開日2015-05-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献Structure of the yeast Bre1 RING domain.
Proteins, 83, 2015
7L6U
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BU of 7l6u by Molmil
Unliganded ELIC in POPC-only nanodiscs at 3.3-Angstrom resolution
分子名称: Gamma-aminobutyric-acid receptor subunit beta-1
著者Kumar, P, Grosman, C.
登録日2020-12-23
公開日2021-06-23
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure and function at the lipid-protein interface of a pentameric ligand-gated ion channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
5WXU
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BU of 5wxu by Molmil
11S globulin from Wrightia tinctoria reveals auxin binding site
分子名称: 11S globulin, 1H-INDOL-3-YLACETIC ACID, CITRATE ANION, ...
著者Kumar, P, Kesari, P, Dhindwal, S, Kumar, P.
登録日2017-01-09
公開日2018-05-23
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A novel function for globulin in sequestering plant hormone: Crystal structure of Wrightia tinctoria 11S globulin in complex with auxin.
Sci Rep, 7, 2017
4NOF
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BU of 4nof by Molmil
Crystal structure of the second Ig domain from mouse Polymeric Immunoglobulin receptor [PSI-NYSGRC-006220]
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Polymeric immunoglobulin receptor
著者Sampathkumar, P, Kumar, P.R, Ahmed, M, Banu, R, Bhosle, R, Calarese, D.A, Celikgil, A, Chamala, S, Chan, M.K, Chowdhury, S, Fiser, A, Garforth, S.J, Glenn, A.S, Hillerich, B, Khafizov, K, Attonito, J, Love, J.D, Patel, H, Patel, R, Seidel, R.D, Smith, B, Stead, M, Casadevall, A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
登録日2013-11-19
公開日2013-12-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of the second Ig domain from mouse Polymeric Immunoglobulin receptor
to be published
5E33
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Structure of human DPP3 in complex with met-enkephalin
分子名称: Dipeptidyl peptidase 3, MAGNESIUM ION, Met-enkephalin, ...
著者Kumar, P, Reithofer, V, Reisinger, M, Pavkov-Keller, T, Wallner, S, Macheroux, P, Gruber, K.
登録日2015-10-01
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.837 Å)
主引用文献Substrate complexes of human dipeptidyl peptidase III reveal the mechanism of enzyme inhibition.
Sci Rep, 6, 2016
5E2Q
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BU of 5e2q by Molmil
Structure of human DPP3 in complex with angiotensin-II
分子名称: Dipeptidyl peptidase 3, MAGNESIUM ION, POTASSIUM ION, ...
著者Kumar, P, Reisinger, M, Reithofer, V, Gruber, K.
登録日2015-10-01
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.404 Å)
主引用文献Substrate complexes of human dipeptidyl peptidase III reveal the mechanism of enzyme inhibition.
Sci Rep, 6, 2016
8UJG
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X-ray crystal structure of Toxoplasma gondii GalNAc-T3 in complex with UDP-GalNAc, Mn2+, and the mono-glycopeptide Srs13.2
分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Kumar, P, Samara, N.L.
登録日2023-10-11
公開日2024-05-15
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献A Toxoplasma gondii O-glycosyltransferase that modulates bradyzoite cyst wall rigidity is distinct from host homologues.
Nat Commun, 15, 2024
8UI1
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X-ray crystal structure of Toxoplasma gondii GalNAc-T3 at pH 7.3
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Glycosyl transferase, ...
著者Kumar, P, Samara, N.L.
登録日2023-10-09
公開日2024-05-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献A Toxoplasma gondii O-glycosyltransferase that modulates bradyzoite cyst wall rigidity is distinct from host homologues.
Nat Commun, 15, 2024
8UJE
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X-ray crystal structure of Toxoplasma gondii GalNAc-T3 in complex with UDP-GalNAc, Mn2+, and Muc5AC-3,13
分子名称: DI(HYDROXYETHYL)ETHER, Glycosyl transferase, MANGANESE (II) ION, ...
著者Kumar, P, Samara, N.L.
登録日2023-10-11
公開日2024-05-15
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Toxoplasma gondii O-glycosyltransferase that modulates bradyzoite cyst wall rigidity is distinct from host homologues.
Nat Commun, 15, 2024
8UJF
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X-ray crystal structure of Toxoplasma gondii GalNAc-T3 in complex with UDP-GalNAc, Mn2+, and Muc5AC-3,13
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycosyl transferase, MANGANESE (II) ION, ...
著者Kumar, P, Samara, N.L.
登録日2023-10-11
公開日2024-05-15
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献A Toxoplasma gondii O-glycosyltransferase that modulates bradyzoite cyst wall rigidity is distinct from host homologues.
Nat Commun, 15, 2024
8UI6
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BU of 8ui6 by Molmil
X-ray crystal structure of Toxoplasma gondii GalNAc-T3 in complex with UDP-GalNAc, Mn2+, and Muc5AC-3,13
分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, Glycosyl transferase, MANGANESE (II) ION, ...
著者Kumar, P, Samara, N.L.
登録日2023-10-10
公開日2024-05-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献A Toxoplasma gondii O-glycosyltransferase that modulates bradyzoite cyst wall rigidity is distinct from host homologues.
Nat Commun, 15, 2024
8UHV
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X-ray crystal structure of Toxoplasma gondii Apo GalNAc-T3
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Glycosyl transferase
著者Kumar, P, Samara, N.L.
登録日2023-10-09
公開日2024-05-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A Toxoplasma gondii O-glycosyltransferase that modulates bradyzoite cyst wall rigidity is distinct from host homologues.
Nat Commun, 15, 2024
8UJH
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BU of 8ujh by Molmil
X-ray crystal structure of Toxoplasma gondii GalNAc-T3 in complex with UDP-GalNAc, Mn2+, and a CST1 diglycopeptide.
分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, GLYCEROL, Glycosyl transferase, ...
著者Kumar, P, Samara, N.L.
登録日2023-10-11
公開日2024-05-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献A Toxoplasma gondii O-glycosyltransferase that modulates bradyzoite cyst wall rigidity is distinct from host homologues.
Nat Commun, 15, 2024
8UHZ
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BU of 8uhz by Molmil
X-ray crystal structure of Toxoplasma gondii GalNAc-T3 in complex with Mn2+
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Glycosyl transferase, ...
著者Kumar, P, Samara, N.L.
登録日2023-10-09
公開日2024-05-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献A Toxoplasma gondii O-glycosyltransferase that modulates bradyzoite cyst wall rigidity is distinct from host homologues.
Nat Commun, 15, 2024
5DUJ
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Crystal structure of ldtMt2 in complex with Faropenem adduct
分子名称: (2R,5R)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-5-[(2R)-tetrahydrofuran-2-yl]-2,5-dihydro-1,3-thiazole-4-carboxylic acid, BETA-MERCAPTOETHANOL, L,D-transpeptidase 2, ...
著者Kumar, P, Lamichhane, G.
登録日2015-09-18
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Non-classical transpeptidases yield insight into new antibacterials.
Nat. Chem. Biol., 13, 2017
5DU7
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Crystal structure of ldtMt2 at 1.79 Angstrom resolution
分子名称: L,D-transpeptidase 2
著者Kumar, P, Lamichhane, G.
登録日2015-09-18
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Non-classical transpeptidases yield insight into new antibacterials.
Nat. Chem. Biol., 13, 2017
5E1I
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Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase 2 with carbapenem drug T210
分子名称: (2S,3R,4R)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-4-(methylsulfanyl)-3,4-dihydro-2H-pyrrole-5-carboxylic acid, GLYCEROL, L,D-transpeptidase 2, ...
著者Kumar, P, Ginell, S.L, Lamichhane, G.
登録日2015-09-29
公開日2016-10-12
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Non-classical transpeptidases yield insight into new antibacterials.
Nat. Chem. Biol., 13, 2017
5DZJ
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Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase 2 with carbapenem drug T206 in conformation A
分子名称: (2~{R},3~{R},4~{R})-4-methyl-3-(2-oxidanylidene-2-propoxy-ethyl)sulfanyl-5-[(2~{S},3~{R})-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2~{H}-pyrrole-2-carboxylic acid, L,D-transpeptidase 2
著者Kumar, P, Ginell, S.L, Lamichhane, G.
登録日2015-09-25
公開日2016-10-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.095 Å)
主引用文献Non-classical transpeptidases yield insight into new antibacterials.
Nat. Chem. Biol., 13, 2017
7K34
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Crystal structure of L-threonine transaldolase from Pseudomonas fluorescens in internal aldimine state
分子名称: SULFATE ION, Threonine aldolase
著者Kumar, P, Bingman, C.A, Buller, A.R.
登録日2020-09-10
公開日2020-12-30
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献l-Threonine Transaldolase Activity Is Enabled by a Persistent Catalytic Intermediate.
Acs Chem.Biol., 16, 2021
3CV0
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BU of 3cv0 by Molmil
Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to T. brucei Phosphoglucoisomerase (PGI) PTS1 peptide
分子名称: 1,2-ETHANEDIOL, Peroxisome targeting signal 1 receptor PEX5, T. brucei PGI PTS1 peptide Ac-FNELSHL
著者Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J.
登録日2008-04-17
公開日2008-06-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.
J.Mol.Biol., 381, 2008
5ZR2
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Crystal Structure of Phosphoserine Phosphatase Mutant (H9A) from Entamoeba histolytica in complex with Phosphoserine
分子名称: DI(HYDROXYETHYL)ETHER, PHOSPHOSERINE, Phosphoglycerate mutase family protein, ...
著者Kumari, P, Gourinath, S.
登録日2018-04-23
公開日2019-04-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural and functional characterisation of phosphoserine phosphatase, that plays critical role in the oxidative stress response in the parasite Entamoeba histolytica.
J.Struct.Biol., 206, 2019
4KN5
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Crystal structure of a putative methylthioadenosine nucleosidase from Weissella paramesenteroides ATCC 33313 (Target NYSGRC-029342 )
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Methylthioadenosine nucleosidase
著者Sampathkumar, P, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2013-05-08
公開日2013-05-29
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of a putative methylthioadenosine nucleosidase from Weissella paramesenteroides ATCC 33313 (Target NYSGRC-029342)
to be published
6M1X
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Crystal structure of Phosphoserine Phosphatase in complex with 3-Phosphoglyceric Acid from Entamoeba histolytica
分子名称: 3-PHOSPHOGLYCERIC ACID, PHOSPHATE ION, Phosphoglycerate mutase family protein
著者Kumari, P, Gourinath, S.
登録日2020-02-26
公開日2021-03-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Structural analysis of EhPSP in complex with 3-phosphoglyceric acid from Entamoeba histolytica reveals a basis for its lack of phosphoglycerate mutase activity.
Int.J.Biol.Macromol., 178, 2021
6FQ3
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Crystal structure of Danio rerio Lin41 filamin-NHL domains in complex with lin-29A 5'UTR 13mer RNA
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase TRIM71, RNA (5'-R(*GP*GP*AP*GP*UP*CP*CP*AP*AP*CP*UP*CP*C)-3')
著者Kumari, P, Aeschimann, F, Gaidatzis, D, Keusch, J.J, Ghosh, P, Neagu, A, Pachulska-Wieczorek, K, Bujnicki, J.M, Gut, H, Grosshans, H, Ciosk, R.
登録日2018-02-13
公開日2018-05-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.
Nat Commun, 9, 2018

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