8UI6

X-ray crystal structure of Toxoplasma gondii GalNAc-T3 in complex with UDP-GalNAc, Mn2+, and Muc5AC-3,13

Summary for 8UI6

• Entry DOI: 10.2210/pdb8ui6/pdb
• Descriptor: Glycosyl transferase, Mucin-5AC, MANGANESE (II) ION, ... (7 entities in total)
• Functional Keywords: gt-a fold galnac glycosyltransferase, mucin-type o-glycosylation, toxoplasma gondii cyst wall glycosylation, transferase
• Biological source: Toxoplasma gondii ME49; More
• Total number of polymer chains: 2
• Total formula weight: 65945.19

Authors

Kumar, P.,Samara, N.L. (deposition date: 2023-10-10, release date: 2024-05-15, Last modification date: 2024-05-22)

• Primary citation: Kumar, P.,Tomita, T.,Gerken, T.A.,Ballard, C.J.,Lee, Y.S.,Weiss, L.M.,Samara, N.L.; A Toxoplasma gondii O-glycosyltransferase that modulates bradyzoite cyst wall rigidity is distinct from host homologues.; Nat Commun, 15:3792-3792, 2024; PubMed: 38710711; DOI: 10.1038/s41467-024-48253-w

Experimental method

X-RAY DIFFRACTION (2.65 Å)