8UI6
X-ray crystal structure of Toxoplasma gondii GalNAc-T3 in complex with UDP-GalNAc, Mn2+, and Muc5AC-3,13
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Glycosyl transferase | polymer | 563 | 63514.1 | 1 | UniProt (A0A125YMZ8) Pfam (PF00535) Pfam (PF02709) Pfam (PF00652) In PDB | Toxoplasma gondii ME49 | |
| 2 | B | Mucin-5AC | polymer | 16 | 1501.6 | 1 | UniProt (P98088) In PDB | Homo sapiens | MUC-5AC,Gastric mucin,Major airway glycoprotein,Mucin-5 subtype AC,tracheobronchial,Tracheobronchial mucin,TBM |
| 3 | A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 4 | A | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) | |||
| 5 | A | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 6 | B | 2-acetamido-2-deoxy-alpha-D-galactopyranose | non-polymer | 221.2 | 1 | Chemie (A2G) | |||
| 7 | water | water | 18.0 | 20 | Chemie (HOH) |
Sequence modifications
A: 74 - 635 (UniProt: A0A125YMZ8)
| PDB | External Database | Details |
|---|---|---|
| Gly 73 | - | expression tag |
| Ser 297 | Gly 297 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65015.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 929.5 | |
| All* | Total formula weight | 65945.2 |
