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8SM3
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Structure of Bacillus cereus VD045 Gabija GajA-GajB Complex
分子名称: Endonuclease GajA, Gabija protein GajB, SULFATE ION
著者Antine, S.P, Mooney, S.E, Johnson, A.G, Kranzusch, P.J.
登録日2023-04-25
公開日2023-11-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of Gabija anti-phage defence and viral immune evasion.
Nature, 625, 2024
8SMF
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BU of 8smf by Molmil
Structure of SPO1 phage Tad2 in complex with 1''-3' gcADPR
分子名称: (2R,3R,3aS,5S,6R,7S,8R,11R,13S,15aR)-2-(6-amino-9H-purin-9-yl)-3,6,7,11,13-pentahydroxyoctahydro-2H,5H,11H,13H-5,8-epoxy-11lambda~5~,13lambda~5~-furo[2,3-g][1,3,5,9,2,4]tetraoxadiphosphacyclotetradecine-11,13-dione, Gp34.65, MAGNESIUM ION
著者Lu, A, Yirmiya, E, Leavitt, A, Avraham, C, Osterman, I, Garb, J, Antine, S.P, Mooney, S.E, Hobbs, S.J, Amitai, G, Sorek, R, Kranzusch, P.J.
登録日2023-04-26
公開日2023-11-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Phages overcome bacterial immunity via diverse anti-defence proteins.
Nature, 625, 2024
8SMD
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BU of 8smd by Molmil
Structure of Clostridium botulinum prophage Tad1 in complex with 1''-3' gcADPR
分子名称: (2R,3R,3aS,5S,6R,7S,8R,11R,13S,15aR)-2-(6-amino-9H-purin-9-yl)-3,6,7,11,13-pentahydroxyoctahydro-2H,5H,11H,13H-5,8-epoxy-11lambda~5~,13lambda~5~-furo[2,3-g][1,3,5,9,2,4]tetraoxadiphosphacyclotetradecine-11,13-dione, ABC transporter ATPase
著者Lu, A, Yirmiya, E, Leavitt, A, Avraham, C, Osterman, I, Garb, J, Antine, S.P, Mooney, S.E, Hobbs, S.J, Amitai, G, Sorek, R, Kranzusch, P.J.
登録日2023-04-26
公開日2023-11-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Phages overcome bacterial immunity via diverse anti-defence proteins.
Nature, 625, 2024
8SME
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BU of 8sme by Molmil
Structure of SPO1 phage Tad2 in apo state
分子名称: Gp34.65
著者Lu, A, Yirmiya, E, Leavitt, A, Avraham, C, Osterman, I, Garb, J, Antine, S.P, Mooney, S.E, Hobbs, S.J, Amitai, G, Sorek, R, Kranzusch, P.J.
登録日2023-04-26
公開日2023-11-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Phages overcome bacterial immunity via diverse anti-defence proteins.
Nature, 625, 2024
8FNW
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BU of 8fnw by Molmil
Structure of RdrA-RdrB complex from Escherichia coli RADAR defense system
分子名称: Adenosine deaminase, Archaeal ATPase, ZINC ION
著者Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J.
登録日2022-12-28
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (6.73 Å)
主引用文献Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.
Cell, 186, 2023
8FNT
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BU of 8fnt by Molmil
Structure of RdrA from Escherichia coli RADAR defense system
分子名称: Archaeal ATPase
著者Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J.
登録日2022-12-28
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.52 Å)
主引用文献Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.
Cell, 186, 2023
8FNV
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BU of 8fnv by Molmil
Structure of RdrB from Escherichia coli RADAR defense system
分子名称: Adenosine deaminase, ZINC ION
著者Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J.
登録日2022-12-28
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.11 Å)
主引用文献Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.
Cell, 186, 2023
8FNU
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BU of 8fnu by Molmil
Structure of RdrA from Streptococcus suis RADAR defense system
分子名称: KAP NTPase domain-containing protein
著者Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J.
登録日2022-12-28
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.
Cell, 186, 2023
8TTO
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BU of 8tto by Molmil
Structure of Hachiman anti-defense 1 (Had1)
分子名称: Hachiman
著者Ragucci, A.E, Antine, S.P, Kranzusch, P.J.
登録日2023-08-14
公開日2023-11-22
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Phages overcome bacterial immunity via diverse anti-defence proteins.
Nature, 625, 2024
8GJW
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BU of 8gjw by Molmil
Structure of a cGAS-like receptor Cv-cGLR1 from C. virginica
分子名称: SULFATE ION, cGAS-like receptor 1
著者Li, Y, Morehouse, B.R, Slavik, K.M, Liu, J, Toyoda, H, Kranzusch, P.J.
登録日2023-03-16
公開日2023-07-05
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献cGLRs are a diverse family of pattern recognition receptors in innate immunity.
Cell, 186, 2023
8GJY
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BU of 8gjy by Molmil
Structure of a cGAS-like receptor Sp-cGLR1 from S. pistillata
分子名称: cGAS-like receptor 1
著者Li, Y, Toyoda, H, Slavik, K.M, Morehouse, B.R, Kranzusch, P.J.
登録日2023-03-16
公開日2023-07-05
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献cGLRs are a diverse family of pattern recognition receptors in innate immunity.
Cell, 186, 2023
8GJX
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BU of 8gjx by Molmil
Structure of the human STING receptor bound to 2'3'-cUA
分子名称: 2'3'-cUA, Stimulator of interferon genes protein
著者Morehouse, B.R, Li, Y, Slavik, K.M, Toyoda, H, Kranzusch, P.J.
登録日2023-03-16
公開日2023-07-05
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献cGLRs are a diverse family of pattern recognition receptors in innate immunity.
Cell, 186, 2023
8GJZ
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BU of 8gjz by Molmil
Structure of a STING receptor from S. pistillata Sp-STING1 bound to 2'3'-cUA
分子名称: 2'3'-cUA, Stimulator of interferon genes protein
著者Li, Y, Toyoda, H, Slavik, K.M, Morehouse, B.R, Kranzusch, P.J.
登録日2023-03-16
公開日2023-07-05
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献cGLRs are a diverse family of pattern recognition receptors in innate immunity.
Cell, 186, 2023
8T9N
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BU of 8t9n by Molmil
Bacillus subtilis RsgI GGG mutant
分子名称: Anti-sigma-I factor RsgI
著者Brogan, A.P, Habib, C, Hobbs, S.J, Kranzusch, P.J, Rudner, D.Z.
登録日2023-06-24
公開日2023-09-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Bacterial SEAL domains undergo autoproteolysis and function in regulated intramembrane proteolysis.
Proc.Natl.Acad.Sci.USA, 120, 2023
8SS1
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BU of 8ss1 by Molmil
Structure of a bacterial death-like domain from Azospirillum sp.
分子名称: Serine protease
著者Johnson, A.G, Kranzusch, P.J.
登録日2023-05-08
公開日2023-06-07
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献CARD-like domains mediate anti-phage defense in bacterial gasdermin systems.
Biorxiv, 2023
8SRZ
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BU of 8srz by Molmil
Structure of a bacterial death-like domain from Lysobacter enzymogenes
分子名称: Probable serine protease FE772_23065
著者Johnson, A.G, Kranzusch, P.J.
登録日2023-05-08
公開日2023-06-07
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献CARD-like domains mediate anti-phage defense in bacterial gasdermin systems.
Biorxiv, 2023
7T26
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BU of 7t26 by Molmil
Structure of phage FBB1 anti-CBASS nuclease Acb1 in apo state
分子名称: Acb1
著者Hobbs, S.J, Wein, T, Lu, A, Morehouse, B.R, Schnabel, J, Sorek, R, Kranzusch, P.J.
登録日2021-12-03
公開日2022-04-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity.
Nature, 605, 2022
7T27
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BU of 7t27 by Molmil
Structure of phage FBB1 anti-CBASS nuclease Acb1-3'3'-cGAMP complex in post reaction state
分子名称: Acb1, SULFATE ION, [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-2-[[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-2-(hydroxymethyl)-4-oxidanyl-oxolan-3-yl]oxy-sulfanyl-phosphoryl]oxymethyl]-4-oxidanyl-oxolan-3-yl]oxy-sulfanyl-phosphinic acid
著者Hobbs, S.J, Wein, T, Lu, A, Morehouse, B.R, Schnabel, J, Sorek, R, Kranzusch, P.J.
登録日2021-12-03
公開日2022-04-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity.
Nature, 605, 2022
7T28
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BU of 7t28 by Molmil
Structure of phage Bsp38 anti-Pycsar nuclease Apyc1 in apo state
分子名称: Putative metal-dependent hydrolase, ZINC ION
著者Hobbs, S.J, Wein, T, Lu, A, Morehouse, B.R, Schnabel, J, Sorek, R, Kranzusch, P.J.
登録日2021-12-03
公開日2022-04-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity.
Nature, 605, 2022
7U2R
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BU of 7u2r by Molmil
Structure of Paenibacillus sp. J14 Apyc1
分子名称: Apyc1, ZINC ION
著者Hobbs, S.J, Wein, T, Lu, A, Morehouse, B.R, Schnabel, J, Sorek, R, Kranzusch, P.J.
登録日2022-02-24
公開日2022-04-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity.
Nature, 605, 2022
7U2S
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BU of 7u2s by Molmil
Structure of Paenibacillus xerothermodurans Apyc1 in the apo state
分子名称: Apyc1, ZINC ION
著者Hobbs, S.J, Wein, T, Lu, A, Morehouse, B.R, Schnabel, J, Sorek, R, Kranzusch, P.J.
登録日2022-02-24
公開日2022-04-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity.
Nature, 605, 2022
7TQN
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BU of 7tqn by Molmil
Structure of human TREX1
分子名称: Three-prime repair exonuclease 1
著者Zhou, W, Richmond-Buccola, D, Kranzusch, P.J.
登録日2022-01-26
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of human TREX1 DNA degradation and autoimmune disease.
Nat Commun, 13, 2022
7TQQ
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BU of 7tqq by Molmil
Structure of human TREX1-DNA complex
分子名称: DNA (5'-D(P*TP*TP*GP*GP*CP*CP*GP*GP*CP*CP*AP*TP*C)-3'), Three-prime repair exonuclease 1
著者Zhou, W, Richmond-Buccola, D, Kranzusch, P.J.
登録日2022-01-26
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of human TREX1 DNA degradation and autoimmune disease.
Nat Commun, 13, 2022
7TQO
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BU of 7tqo by Molmil
Structure of human TREX1
分子名称: Three-prime repair exonuclease 1
著者Zhou, W, Richmond-Buccola, D, Kranzusch, P.J.
登録日2022-01-26
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural basis of human TREX1 DNA degradation and autoimmune disease.
Nat Commun, 13, 2022
7TQP
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BU of 7tqp by Molmil
Structure of human TREX1
分子名称: SULFATE ION, Three-prime repair exonuclease 1
著者Zhou, W, Richmond-Buccola, D, Kranzusch, P.J.
登録日2022-01-26
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis of human TREX1 DNA degradation and autoimmune disease.
Nat Commun, 13, 2022

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