2MN1
 
 | | Solution Structure of kalata B1[W23WW] | | 分子名称: | kalata B1[W23WW] | | 著者 | Henriques, S.T, Huang, Y.H, Chaousis, S, Wang, C.K, Craik, D.J. | | 登録日 | 2014-03-26 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Anticancer and toxic properties of cyclotides are dependent on phosphatidylethanolamine phospholipid targeting.
Chembiochem, 15, 2014
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6L0I
 | | Crystal structure of dihydroorotase in complex with malate at pH6.5 from Saccharomyces cerevisiae | | 分子名称: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | | 登録日 | 2019-09-26 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil.
Biochem.Biophys.Res.Commun., 551, 2021
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7CA0
 | | Crystal structure of dihydroorotase in complex with 5-fluoroorotic acid from Saccharomyces cerevisiae | | 分子名称: | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, ZINC ION | | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | | 登録日 | 2020-06-08 | | 公開日 | 2021-06-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Complexed Crystal Structure of Saccharomyces cerevisiae Dihydroorotase with Inhibitor 5-Fluoroorotate Reveals a New Binding Mode.
Bioinorg Chem Appl, 2021, 2021
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7CA1
 | | Crystal structure of dihydroorotase in complex with plumbagin from Saccharomyces cerevisiae | | 分子名称: | (2S)-2-hydroxybutanedioic acid, 5-hydroxy-2-methylnaphthalene-1,4-dione, Dihydroorotase, ... | | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | | 登録日 | 2020-06-08 | | 公開日 | 2021-06-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Plumbagin, a Natural Product with Potent Anticancer Activities, Binds to and Inhibits Dihydroorotase, a Key Enzyme in Pyrimidine Biosynthesis.
Int J Mol Sci, 22, 2021
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7F2N
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7F25
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7FBP
 | | FXIIa-cMCoFx1 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor XIIa light chain, cMCoFx1 | | 著者 | Sengoku, T, Liu, W, de Veer, S.J, Huang, Y.H, Okada, C, Zdenek, C.N, Fry, B.G, Swedberg, J.E, Passioura, T, Craik, D.J, Suga, H, Ogata, K. | | 登録日 | 2021-07-12 | | 公開日 | 2021-11-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | An Ultrapotent and Selective Cyclic Peptide Inhibitor of Human beta-Factor XIIa in a Cyclotide Scaffold.
J.Am.Chem.Soc., 143, 2021
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8HFD
 | | Crystal structure of allantoinase from E. coli BL21 | | 分子名称: | Allantoinase, DI(HYDROXYETHYL)ETHER, ZINC ION | | 著者 | Lin, E.S, Huang, H.Y, Yang, P.C, Liu, H.W, Huang, C.Y. | | 登録日 | 2022-11-10 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Crystal Structure of Allantoinase from Escherichia coli BL21: A Molecular Insight into a Role of the Active Site Loops in Catalysis.
Molecules, 28, 2023
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4N74
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2MT8
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5YUN
 | | Crystal structure of SSB complexed with myc | | 分子名称: | 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, Single-stranded DNA-binding protein | | 著者 | Huang, Y.H, Huang, C.Y. | | 登録日 | 2017-11-22 | | 公開日 | 2018-10-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Crystal structure of SSB complexed with inhibitor myricetin.
Biochem. Biophys. Res. Commun., 504, 2018
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6GOV
 | | Structure of THE RNA POLYMERASE LAMBDA-BASED ANTITERMINATION COMPLEX | | 分子名称: | 30S ribosomal protein S10, Antitermination protein N, DNA (I), ... | | 著者 | Loll, B, Krupp, F, Said, N, Huang, Y, Buerger, J, Mielke, T, Spahn, C.M.T, Wahl, M.C. | | 登録日 | 2018-06-04 | | 公開日 | 2019-02-13 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor.
Mol.Cell, 74, 2019
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6DKZ
 | | Racemic structure of ribifolin, an orbitide from Jatropha ribifolia | | 分子名称: | ribifolin | | 著者 | Wang, C.K, King, G.J, Ramalho, S.D. | | 登録日 | 2018-05-31 | | 公開日 | 2018-11-14 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (0.99 Å) | | 主引用文献 | Synthesis, Racemic X-ray Crystallographic, and Permeability Studies of Bioactive Orbitides from Jatropha Species.
J. Nat. Prod., 81, 2018
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6DKY
 | | Crystal structure of ribifolin, an orbitide from Jatropha ribifolia | | 分子名称: | ILE-LEU-GLY-SER-ILE-ILE-LEU-GLY | | 著者 | Wang, C.K, Ramalho, S.D, King, G.J, Craik, D.J. | | 登録日 | 2018-05-31 | | 公開日 | 2018-11-07 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (1.239 Å) | | 主引用文献 | Synthesis, Racemic X-ray Crystallographic, and Permeability Studies of Bioactive Orbitides from Jatropha Species.
J. Nat. Prod., 81, 2018
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5MS0
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4APV
 | | The Klebsiella pneumoniae primosomal PriB protein: identification, crystal structure, and ssDNA binding mode | | 分子名称: | PRIMOSOMAL REPLICATION PROTEIN N | | 著者 | Lo, Y.H, Huang, Y.H, Hsiao, C.D, Huang, C.Y. | | 登録日 | 2012-04-06 | | 公開日 | 2012-04-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.095 Å) | | 主引用文献 | Crystal Structure and DNA-Binding Mode of Klebsiella Pneumoniae Primosomal Prib Protein.
Genes Cells, 17, 2012
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6ZCA
 | | Structure of the B. subtilis RNA POLYMERASE in complex with HelD (monomer) | | 分子名称: | DNA helicase, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Pei, H.-P, Hilal, T, Huang, Y.-H, Said, N, Loll, B, Wahl, M.C. | | 登録日 | 2020-06-10 | | 公開日 | 2020-10-14 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | The delta subunit and NTPase HelD institute a two-pronged mechanism for RNA polymerase recycling.
Nat Commun, 11, 2020
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6ZFB
 | | Structure of the B. subtilis RNA POLYMERASE in complex with HelD (dimer) | | 分子名称: | DNA helicase, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Pei, H.-P, Hilal, T, Huang, Y.-H, Said, N, Loll, B, Wahl, M.C. | | 登録日 | 2020-06-17 | | 公開日 | 2020-10-14 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | The delta subunit and NTPase HelD institute a two-pronged mechanism for RNA polymerase recycling.
Nat Commun, 11, 2020
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5WE3
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5LM7
 | | Crystal structure of the lambda N-Nus factor complex | | 分子名称: | 30S ribosomal protein S10, Antitermination protein N, N utilization substance protein B homolog, ... | | 著者 | Said, N, Santos, K, Weber, G, Wahl, M.C. | | 登録日 | 2016-07-29 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Structural basis for lambda N-dependent processive transcription antitermination.
Nat Microbiol, 2, 2017
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5LM9
 | | Structure of E. coli NusA | | 分子名称: | MAGNESIUM ION, SULFATE ION, Transcription termination/antitermination protein NusA | | 著者 | Said, N, Weber, G, Santos, K, Wahl, M.C. | | 登録日 | 2016-07-29 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.143 Å) | | 主引用文献 | Structural basis for lambda N-dependent processive transcription antitermination.
Nat Microbiol, 2, 2017
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6PI2
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6PIN
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6PI3
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6PIO
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