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1B2S
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BU of 1b2s by Molmil
STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE
分子名称: PROTEIN (BARNASE), PROTEIN (BARSTAR), SULFATE ION
著者Vaughan, C.K, Buckle, A.M, Fersht, A.R.
登録日1998-11-30
公開日1998-12-08
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structural response to mutation at a protein-protein interface.
J.Mol.Biol., 286, 1999
1B27
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BU of 1b27 by Molmil
STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE
分子名称: PROTEIN (BARNASE), PROTEIN (BARSTAR)
著者Vaughan, C.K, Buckle, A.M, Fersht, A.R.
登録日1998-12-04
公開日1998-12-09
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural response to mutation at a protein-protein interface.
J.Mol.Biol., 286, 1999
1B2U
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BU of 1b2u by Molmil
STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE
分子名称: PROTEIN (BARNASE), PROTEIN (BARSTAR)
著者Vaughan, C.K, Buckle, A.M, Fersht, A.R.
登録日1998-12-01
公開日1998-12-09
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural response to mutation at a protein-protein interface.
J.Mol.Biol., 286, 1999
2DG9
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BU of 2dg9 by Molmil
FK506-binding protein mutant WL59 complexed with Rapamycin
分子名称: FK506-binding protein 1A, GLYCEROL, RAPAMYCIN IMMUNOSUPPRESSANT DRUG
著者Fulton, K.F, Jackson, S.E, Buckle, A.M.
登録日2006-03-09
公開日2006-04-25
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Energetic and structural analysis of the role of tryptophan 59 in FKBP12
Biochemistry, 42, 2003
2AK4
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BU of 2ak4 by Molmil
Crystal Structure of SB27 TCR in complex with HLA-B*3508-13mer peptide
分子名称: Beta-2-microglobulin, EBV peptide LPEPLPQGQLTAY, HLA-B35 variant, ...
著者Tynan, F.E, Burrows, S.R, Buckle, A.M, Clements, C.S, Borg, N.A, Miles, J.J, Beddoe, T, Whisstock, J.C, Wilce, M.C, Silins, S.L, Burrows, J.M, Kjer-Nielsen, L, Konstenko, L, Purcell, A.W, McCluskey, J, Rossjohn, J.
登録日2005-08-03
公開日2005-10-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide
Nat.Immunol., 6, 2005
2DUT
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BU of 2dut by Molmil
Crystal structure of a M-loop deletion variant of MENT in the native conformation
分子名称: Heterochromatin-associated protein MENT
著者Whisstock, J.C, Buckle, A.M, McGowan, S, Irving, J.A.
登録日2006-07-26
公開日2006-08-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation
Embo J., 25, 2006
3JZ4
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BU of 3jz4 by Molmil
Crystal structure of E. coli NADP dependent enzyme
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Succinate-semialdehyde dehydrogenase [NADP+]
著者Langendorf, C.G, Key, T.L.G, Fenalti, G, Kan, W.T, Buckle, A.M, Caradoc-Davies, T, Tuck, K.L, Law, R.H.P, Whisstock, J.C.
登録日2009-09-22
公開日2010-03-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The X-ray crystal structure of Escherichia coli succinic semialdehyde dehydrogenase; structural insights into NADP+/enzyme interactions.
Plos One, 5, 2010
3EBG
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BU of 3ebg by Molmil
Structure of the M1 Alanylaminopeptidase from malaria
分子名称: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ...
著者McGowan, S, Porter, C.J, Buckle, A.M, Whisstock, J.C.
登録日2008-08-27
公開日2009-01-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase
Proc.Natl.Acad.Sci.USA, 106, 2009
3EBH
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BU of 3ebh by Molmil
Structure of the M1 Alanylaminopeptidase from malaria complexed with bestatin
分子名称: 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, GLYCEROL, M1 family aminopeptidase, ...
著者McGowan, S, Porter, C.J, Buckle, A.M, Whisstock, J.C.
登録日2008-08-27
公開日2009-01-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase
Proc.Natl.Acad.Sci.USA, 106, 2009
2PEE
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BU of 2pee by Molmil
Crystal Structure of a Thermophilic Serpin, Tengpin, in the Native State
分子名称: GLYCEROL, SULFATE ION, Serine protease inhibitor
著者Zhang, Q.W, Buckle, A.M, Whisstock, J.C.
登録日2007-04-02
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The N terminus of the serpin, tengpin, functions to trap the metastable native state.
Embo Rep., 8, 2007
2NW0
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BU of 2nw0 by Molmil
Crystal structure of a lysin
分子名称: ACETATE ION, PlyB
著者Porter, C.J, Buckle, A.M, Whisstock, J.C.
登録日2006-11-14
公開日2006-12-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The 1.6 A Crystal Structure of the Catalytic Domain of PlyB, a Bacteriophage Lysin Active Against Bacillus anthracis.
J.Mol.Biol., 366, 2007
3EBI
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BU of 3ebi by Molmil
Structure of the M1 Alanylaminopeptidase from malaria complexed with the phosphinate dipeptide analog
分子名称: (2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid, GLYCEROL, M1 family aminopeptidase, ...
著者McGowan, S, Porter, C.J, Buckle, A.M, Whisstock, J.C.
登録日2008-08-27
公開日2009-01-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase
Proc.Natl.Acad.Sci.USA, 106, 2009
2PEF
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BU of 2pef by Molmil
Crystal Structure of a Thermophilic Serpin, Tengpin, in the Latent State
分子名称: Serine protease inhibitor
著者Zhang, Q.W, Buckle, A.M, Whisstock, J.C.
登録日2007-04-03
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The N terminus of the serpin, tengpin, functions to trap the metastable native state.
Embo Rep., 8, 2007
1B2Z
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BU of 1b2z by Molmil
DELETION OF A BURIED SALT BRIDGE IN BARNASE
分子名称: PROTEIN (BARNASE), ZINC ION
著者Vaughan, C.K, Harryson, P, Buckle, A.M, Oliveberg, M, Fersht, A.R.
登録日1998-12-03
公開日1998-12-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase.
Acta Crystallogr.,Sect.D, 58, 2002
1B20
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BU of 1b20 by Molmil
DELETION OF A BURIED SALT-BRIDGE IN BARNASE
分子名称: PROTEIN (BARNASE), ZINC ION
著者Vaughan, C.K, Harryson, P, Buckle, A.M, Oliveberg, M, Fersht, A.R.
登録日1998-12-03
公開日1998-12-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase.
Acta Crystallogr.,Sect.D, 58, 2002
1B21
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BU of 1b21 by Molmil
DELETION OF A BURIED SALT BRIDGE IN BARNASE
分子名称: PROTEIN (BARNASE), ZINC ION
著者Vaughan, C.K, Harryson, P, Buckle, A.M, Oliveberg, M, Fersht, A.R.
登録日1998-12-03
公開日1998-12-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase.
Acta Crystallogr.,Sect.D, 58, 2002
1B2X
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BU of 1b2x by Molmil
BARNASE WILDTYPE STRUCTURE AT PH 7.5 FROM A CRYO_COOLED CRYSTAL AT 100K
分子名称: PROTEIN (BARNASE), ZINC ION
著者Harrison, P, Vaughan, C.K, Buckle, A.M, Fersht, A.R.
登録日1998-12-03
公開日1998-12-09
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase.
Acta Crystallogr.,Sect.D, 58, 2002
1BRK
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BU of 1brk by Molmil
BARNASE MUTANT WITH ILE 96 REPLACED BY ALA
分子名称: BARNASE, ZINC ION
著者Cramer, P.C, Buckle, A, Fersht, A.
登録日1995-03-09
公開日1995-07-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
1BRJ
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BU of 1brj by Molmil
BARNASE MUTANT WITH ILE 88 REPLACED BY ALA
分子名称: BARNASE, ZINC ION
著者Cramer, P.C, Buckle, A, Fersht, A.
登録日1995-03-09
公開日1995-07-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
1BRH
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BU of 1brh by Molmil
BARNASE MUTANT WITH LEU 14 REPLACED BY ALA
分子名称: BARNASE, ZINC ION
著者Cramer, P.C, Buckle, A, Fersht, A.
登録日1995-03-09
公開日1995-07-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
1BRI
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BU of 1bri by Molmil
BARNASE MUTANT WITH ILE 76 REPLACED BY ALA
分子名称: BARNASE
著者Cramer, P.C, Buckle, A, Fersht, A.
登録日1995-03-09
公開日1995-07-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
4UZM
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BU of 4uzm by Molmil
Shotgun proteolysis: A practical application
分子名称: PUTATIVE MEMBRANE PROTEIN IGAA HOMOLOG
著者Allen, M.D, Bycroft, M, Freund, S.M.V, Christ, D.
登録日2014-09-05
公開日2014-09-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure of a Soluble Fragment Derived from a Membrane Protein by Shotgun Proteolysis.
Protein Eng.Des.Sel., 28, 2015
4PCP
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BU of 4pcp by Molmil
Crystal structure of Phosphotriesterase variant R0
分子名称: CACODYLATE ION, Phosphotriesterase variant PTE-R0, ZINC ION
著者Campbell, E, Kaltenbach, M, Tokuriki, N, Jackson, C.J.
登録日2014-04-16
公開日2015-05-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献The role of protein dynamics in the evolution of new enzyme function.
Nat. Chem. Biol., 12, 2016
3TUU
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BU of 3tuu by Molmil
Structure of dihydrodipicolinate synthase from the common grapevine
分子名称: BROMIDE ION, CHLORIDE ION, dihydrodipicolinate synthase
著者Perugini, M.A, Dobson, R.C, Atkinson, S.C.
登録日2011-09-19
公開日2012-07-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal, Solution and In silico Structural Studies of Dihydrodipicolinate Synthase from the Common Grapevine.
Plos One, 7, 2012
6BVH
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BU of 6bvh by Molmil
Trypsin complexed with a modified sunflower trypsin inhibitor, SFTI-TCTR(N12,N14)
分子名称: CALCIUM ION, Cationic trypsin, GLYCEROL, ...
著者Riley, B.T, Chen, X.
登録日2017-12-13
公開日2018-12-19
最終更新日2019-01-30
実験手法X-RAY DIFFRACTION (1.927 Å)
主引用文献Potent, multi-target serine protease inhibition achieved by a simplified beta-sheet motif.
PLoS ONE, 14, 2019

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