2DG9

FK506-binding protein mutant WL59 complexed with Rapamycin

Summary for 2DG9

Entry DOI	10.2210/pdb2dg9/pdb
Related	2DG3 2DG4
Descriptor	FK506-binding protein 1A, RAPAMYCIN IMMUNOSUPPRESSANT DRUG, GLYCEROL, ... (4 entities in total)
Functional Keywords	immunophilin, isomerase, rotamase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P62942
Total number of polymer chains	1
Total formula weight	12769.72
Authors	Fulton, K.F.,Jackson, S.E.,Buckle, A.M. (deposition date: 2006-03-09, release date: 2006-04-25, Last modification date: 2021-11-10)
Primary citation	Fulton, K.F.,Jackson, S.E.,Buckle, A.M. Energetic and structural analysis of the role of tryptophan 59 in FKBP12 Biochemistry, 42:2364-2372, 2003 Cited by PubMed: 12600203 DOI: 10.1021/bi020564a PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation