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6CJK
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BU of 6cjk by Molmil
Anti HIV Fab 10A
分子名称: ACETATE ION, GLYCEROL, Immunoglobulin Fab heavy chain, ...
著者Hangartner, L, Ward, A.B, Wilson, I.A, Oyen, D.
登録日2018-02-26
公開日2018-08-15
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.795 Å)
主引用文献Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization.
Immunity, 49, 2018
6E3H
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BU of 6e3h by Molmil
Crystal structure of S9-3-37 bound to H5 influenza hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
著者Wu, N.C, Wilson, I.A.
登録日2018-07-14
公開日2018-09-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The D3-9 gene segment encodes for recurring and adaptable binding motifs in broadly neutralizing antibodies to influenza virus
Cell Host Microbe, 2018
6BXA
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BU of 6bxa by Molmil
Crystal structure of N-terminal fragment of Zebrafish Toll-Like Receptor 5 (TLR5) with Lamprey Variable Lymphocyte Receptor 2 (VLR2) bound
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gunn, R.J, Wilson, I.A, Cooper, M.D, Herrin, B.R.
登録日2017-12-18
公開日2018-05-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.298 Å)
主引用文献VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies.
J. Mol. Biol., 430, 2018
4N5K
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BU of 4n5k by Molmil
Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with LSTa
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
著者Xu, R, Wilson, I.A.
登録日2013-10-10
公開日2013-12-18
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.7053 Å)
主引用文献Preferential recognition of avian-like receptors in human influenza A H7N9 viruses.
Science, 342, 2013
6BXD
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BU of 6bxd by Molmil
Crystal structure of Variable Lymphocyte Receptor 2 (VLR2)
分子名称: 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, SULFATE ION, Variable Lymphocyte Receptor 2
著者Gunn, R.J, Wilson, I.A, Cooper, M.D, Herrin, B.R.
登録日2017-12-18
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.103 Å)
主引用文献VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies.
J. Mol. Biol., 430, 2018
6BZW
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BU of 6bzw by Molmil
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the GL precursor of the broadly neutralizing antibody AP33
分子名称: AP33 GL Heavy Chain, AP33 GL Light Chain, E2 AS412 peptide
著者Tzarum, N, Aleman, F, Wilson, I.A, Law, M.
登録日2017-12-26
公開日2018-06-20
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4MWF
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BU of 4mwf by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core bound to broadly neutralizing antibody AR3C
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Kong, L, Wilson, I.A, Law, M.
登録日2013-09-24
公開日2013-12-11
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.645 Å)
主引用文献Hepatitis C virus e2 envelope glycoprotein core structure.
Science, 342, 2013
4N64
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BU of 4n64 by Molmil
Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with a biantennary glycan receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
著者Xu, R, Wilson, I.A.
登録日2013-10-11
公開日2013-12-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7014 Å)
主引用文献Preferential recognition of avian-like receptors in human influenza A H7N9 viruses.
Science, 342, 2013
4N5J
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BU of 4n5j by Molmil
Crystal structure of hemagglutinin from an H7N9 influenza virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
著者Xu, R, Wilson, I.A.
登録日2013-10-10
公開日2013-12-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Preferential recognition of avian-like receptors in human influenza A H7N9 viruses.
Science, 342, 2013
4MZE
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BU of 4mze by Molmil
Crystal structure of hPIV3 hemagglutinin-neuraminidase, H552Q/Q559R mutant
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Xu, R, Wilson, I.A.
登録日2013-09-30
公開日2013-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Interaction between the hemagglutinin-neuraminidase and fusion glycoproteins of human parainfluenza virus type III regulates viral growth in vivo.
MBio, 4, 2013
8E1P
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BU of 8e1p by Molmil
Crystal structure of BG505 SOSIP.v4.1-GT1.2 trimer in complex with gl-PGV20 and PGT124 Fabs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505-SOSIP.v4.1-GT1.2gp120, ...
著者Sarkar, A, Kumar, S, Wilson, I.A.
登録日2022-08-11
公開日2023-06-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.82 Å)
主引用文献Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions.
Cell Rep Med, 4, 2023
7RDM
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BU of 7rdm by Molmil
Crystal structure of PCDN-38B, a broadly neutralizing anti-HIV antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, GLYCEROL, ...
著者Omorodion, O, Wilson, I.A.
登録日2021-07-09
公開日2021-11-10
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structural and Biochemical Characterization of Cysteinylation in Broadly Neutralizing Antibodies to HIV-1.
J.Mol.Biol., 433, 2021
7RDK
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BU of 7rdk by Molmil
Crystal structure of PCDN-16B, an anti-HIV antibody from the PCDN bnAb lineage (cysteinylated state)
分子名称: 1,2-ETHANEDIOL, CYSTEINE, GLYCEROL, ...
著者Omorodion, O, Wilson, I.A.
登録日2021-07-09
公開日2021-11-10
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Structural and Biochemical Characterization of Cysteinylation in Broadly Neutralizing Antibodies to HIV-1.
J.Mol.Biol., 433, 2021
7RDH
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BU of 7rdh by Molmil
Crystal structure of the de novo designed binding protein H3mb in complex with the 1968 influenza A virus hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, De novo designed protein H3mb, ...
著者Kadam, R.U, Wilson, I.A.
登録日2021-07-09
公開日2022-05-04
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
7RDJ
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BU of 7rdj by Molmil
Crystal structure of PCDN-16B, an anti-HIV antibody from the PCDN bnAb lineage (non-cysteinylated state)
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PCDN-16B Fab heavy chain, ...
著者Omorodion, O, Wilson, I.A.
登録日2021-07-09
公開日2021-11-10
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural and Biochemical Characterization of Cysteinylation in Broadly Neutralizing Antibodies to HIV-1.
J.Mol.Biol., 433, 2021
7RDL
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BU of 7rdl by Molmil
Crystal structure of PCDN-22A, an anti-HIV antibody from the PCDN bnAb lineage
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PCDN-22A Fab heavy chain, PCDN-22A Fab light chain
著者Omorodion, O, Wilson, I.A.
登録日2021-07-09
公開日2021-11-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structural and Biochemical Characterization of Cysteinylation in Broadly Neutralizing Antibodies to HIV-1.
J.Mol.Biol., 433, 2021
7S0I
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BU of 7s0i by Molmil
CRYSTAL STRUCTURE OF N1 NEURAMINIDASE FROM A/Michigan/45/2015(H1N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ...
著者Zhu, X, Wilson, I.A.
登録日2021-08-30
公開日2021-12-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.892 Å)
主引用文献A Novel Recombinant Influenza Virus Neuraminidase Vaccine Candidate Stabilized by a Measles Virus Phosphoprotein Tetramerization Domain Provides Robust Protection from Virus Challenge in the Mouse Model.
Mbio, 12, 2021
7RTP
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BU of 7rtp by Molmil
Structure of full-length human lambda-6A light chain JTO in complex with urea stabilizer 20 [1-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)-3-(pyridin-3-ylmethyl)urea]
分子名称: JTO light chain, N-{2-[7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl]ethyl}-N'-[(pyridin-3-yl)methyl]urea, PHOSPHATE ION
著者Yan, N.L, Wilson, I.A, Kelly, J.W.
登録日2021-08-13
公開日2022-02-16
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site.
Bioorg.Med.Chem.Lett., 60, 2022
7S5Q
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BU of 7s5q by Molmil
Crystal structure of SARS-CoV-2 B.1.351 variant receptor binding domain in complex with neutralizing antibodies CS44 and COVA1-16
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA1-16 Heavy chain, ...
著者Yuan, M, Wilson, I.A.
登録日2021-09-11
公開日2022-03-09
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies.
Science, 375, 2022
7S5R
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BU of 7s5r by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibodies CV07-287 and COVA1-16
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA1-16 Heavy chain, ...
著者Yuan, M, Wilson, I.A.
登録日2021-09-11
公開日2022-03-09
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies.
Science, 375, 2022
7RXP
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BU of 7rxp by Molmil
Fab1512 in complex with the C-terminal alpha-TSR domain of P. falciparum
分子名称: Circumsporozoite protein, Fab1512 heavy chain, Fab1512 light chain
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2021-08-23
公開日2022-03-16
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.761 Å)
主引用文献A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7S5P
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BU of 7s5p by Molmil
Crystal structure of SARS-CoV-2 B.1.351 variant receptor binding domain in complex with neutralizing antibody CS23
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CS23 Heavy chain, ...
著者Yuan, M, Wilson, I.A.
登録日2021-09-11
公開日2022-03-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies.
Science, 375, 2022
7RXI
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BU of 7rxi by Molmil
Fab234 in complex with the C-terminal alpha-TSR domain of P. falciparum
分子名称: Circumsporozoite protein, Fab234 heavy chain, Fab234 light chain
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2021-08-23
公開日2022-03-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7RXJ
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BU of 7rxj by Molmil
Fab236 in complex with the C-terminal alpha-TSR domain of P. falciparum
分子名称: Circumsporozoite protein, Fab236 heavy chain, Fab236 light chain
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2021-08-23
公開日2022-03-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.345 Å)
主引用文献A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7S0X
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Fab352 in complex with the C-terminal alphaTSR domain of P. falciparum
分子名称: Circumsporozoite protein, Fab352 heavy chain, Fab352 light chain
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2021-08-31
公開日2022-03-16
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022

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