1NI9
 
 | | 2.0 A structure of glycerol metabolism protein from E. coli | | 分子名称: | Protein glpX, SULFATE ION | | 著者 | Sanishvili, R, Brunzelle, J, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2002-12-23 | | 公開日 | 2003-07-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and Biochemical Characterization of the Type II Fructose-1,6-bisphosphatase GlpX from Escherichia coli.
J.Biol.Chem., 284, 2009
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8C9E
 | | Priestia megaterium mupirocin-sensitive isoleucyl-tRNA synthetase 1 complexed with an isoleucyl-adenylate analogue | | 分子名称: | CHLORIDE ION, Isoleucine--tRNA ligase, LITHIUM ION, ... | | 著者 | Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Ban, N, Gruic-Sovulj, I. | | 登録日 | 2023-01-21 | | 公開日 | 2023-08-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif.
Nat Commun, 14, 2023
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3MU1
 | | Comparison of the character and the speed of X-ray-induced structural changes of porcine pancreatic elastase at two temperatures, 100 and 15K. The data set was collected from region A of the crystal. Fifth step of radiation damage | | 分子名称: | Chymotrypsin-like elastase family member 1, SODIUM ION, SULFATE ION | | 著者 | Petrova, T, Ginell, S, Mitschler, A, Cousido-Siah, A, Hazemann, I, Podjarny, A, Joachimiak, A. | | 登録日 | 2010-05-01 | | 公開日 | 2010-05-12 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | X-ray-induced deterioration of disulfide bridges at atomic resolution.
Acta Crystallogr.,Sect.D, 66, 2010
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7B76
 | | Crystal structure of the effector AvrLm5-9 from Leptosphaeria maculans | | 分子名称: | Avirulence protein LmJ1, IODIDE ION | | 著者 | Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I. | | 登録日 | 2020-12-09 | | 公開日 | 2022-01-12 | | 最終更新日 | 2023-03-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins.
Plos Pathog., 18, 2022
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8B7Q
 | | Cryo-EM structure for the mouse LEPR-CRH2:Leptin:LEPR-Ig complex following symmetry expansion in combination with local refinement | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor | | 著者 | Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A. | | 登録日 | 2022-09-30 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-04-26 | | 実験手法 | ELECTRON MICROSCOPY (4.02 Å) | | 主引用文献 | Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
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8AA3
 | | Core SusCD transporter units from the inactive levan utilisome in the presence of levan fructo-oligosaccharides DP 15-25 | | 分子名称: | MAGNESIUM ION, SusC homolog, SusD homolog, ... | | 著者 | White, J.B.R, Silale, A, Ranson, N.A, van den Berg, B. | | 登録日 | 2022-06-29 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-06-21 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Outer membrane utilisomes mediate glycan uptake in gut Bacteroidetes.
Nature, 618, 2023
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5G2T
 | | BT1596 in complex with its substrate 4,5 unsaturated uronic acid alpha 1,4 D-Glucosamine-2-N, 6-O-disulfate | | 分子名称: | 1,2-ETHANEDIOL, 2-O GLYCOSAMINOGLYCAN SULFATASE, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid, ... | | 著者 | Cartmell, A, Lowe, E.C, Basle, A, Crouch, L.I, Czjzek, M, Turnbull, J, Henrissat, B, Terrapon, N, Thomas, S, Murray, H, Firbank, S.J, Bolam, D.N. | | 登録日 | 2016-04-13 | | 公開日 | 2017-05-24 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8A9Y
 | | Substrate-free levan utilisation machinery (utilisome) | | 分子名称: | DUF4960 domain-containing protein, Glycoside hydrolase family 32, MAGNESIUM ION, ... | | 著者 | White, J.B.R, Silale, A, Ranson, N.A, van den Berg, B. | | 登録日 | 2022-06-29 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-06-21 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Outer membrane utilisomes mediate glycan uptake in gut Bacteroidetes.
Nature, 618, 2023
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8AA4
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6B7B
 | | Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with 5-methoxy-2-methyl-1H-indole | | 分子名称: | 5-methoxy-2-methyl-1H-indole, DIMETHYL SULFOXIDE, PYROPHOSPHATE 2-, ... | | 著者 | Proudfoot, A.W, Bussiere, D, Lingel, A. | | 登録日 | 2017-10-03 | | 公開日 | 2017-12-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | | 主引用文献 | High-Confidence Protein-Ligand Complex Modeling by NMR-Guided Docking Enables Early Hit Optimization.
J. Am. Chem. Soc., 139, 2017
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8AA1
 | | Core SusCD transporter units from the levan utilisome with levan fructo-oligosaccharides DP 8-12 | | 分子名称: | MAGNESIUM ION, SusC homolog, SusD homolog, ... | | 著者 | White, J.B.R, Silale, A, Ranson, N.A, van den Berg, B. | | 登録日 | 2022-06-29 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-06-21 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Outer membrane utilisomes mediate glycan uptake in gut Bacteroidetes.
Nature, 618, 2023
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8AA0
 | | Levan utilisation machinery (utilisome) with levan fructo-oligosaccharides DP 8-12 | | 分子名称: | DUF4960 domain-containing protein, Glycoside hydrolase family 32, MAGNESIUM ION, ... | | 著者 | White, J.B.R, Silale, A, Ranson, N.A, van den Berg, B. | | 登録日 | 2022-06-29 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-06-21 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Outer membrane utilisomes mediate glycan uptake in gut Bacteroidetes.
Nature, 618, 2023
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8AA2
 | | Inactive levan utilisation machinery (utilisome) in the presence of levan fructo-oligosaccharides DP 15-25 | | 分子名称: | DUF4960 domain-containing protein, Glycoside hydrolase family 32, MAGNESIUM ION, ... | | 著者 | White, J.B.R, Silale, A, Ranson, N.A, van den Berg, B. | | 登録日 | 2022-06-29 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-06-21 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Outer membrane utilisomes mediate glycan uptake in gut Bacteroidetes.
Nature, 618, 2023
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7UUK
 | | Crystal structure of aminoglycoside resistance enzyme ApmA, complex with tobramycin | | 分子名称: | Aminocyclitol acetyltransferase ApmA, CHLORIDE ION, TOBRAMYCIN | | 著者 | Stogios, P.J, Evdokimova, E, Di Leo, R, Bordeleau, E, Wright, G.D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID) | | 登録日 | 2022-04-28 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | | 主引用文献 | Mechanistic plasticity in ApmA enables aminoglycoside promiscuity for resistance.
Nat.Chem.Biol., 20, 2024
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5I8M
 | | Bicyclic antimibrocial peptides | | 分子名称: | 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid, CALCIUM ION, DLS-LYS-CYS-LYS-LEU-CYS-LEU-LYS-NH2, ... | | 著者 | Di Bonaventura, I, Jin, X, Visini, R, Michaud, G, Robadey, M, Koehler, T, van Delden, C, Stocker, A, Darbre, T, Reymond, J.-L. | | 登録日 | 2016-02-19 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Chemical space guided discovery of antimicrobial bridged bicyclic peptides against Pseudomonas aeruginosa and its biofilms.
Chem Sci, 8, 2017
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5ID7
 | | Crystal structure of human serum albumin in complex with phosphorodithioate derivative of myristoyl cyclic phosphatidic acid (cPA) | | 分子名称: | (4S)-2-sulfanylidene-4-[(tetradecanoyloxy)methyl]-1,3,2lambda~5~-dioxaphospholane-2-thiolate, DI(HYDROXYETHYL)ETHER, Serum albumin, ... | | 著者 | Sekula, B, Bujacz, A, Rytczak, P, Bujacz, G. | | 登録日 | 2016-02-24 | | 公開日 | 2016-05-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Structural evidence of the species-dependent albumin binding of the modified cyclic phosphatidic acid with cytotoxic properties.
Biosci.Rep., 36, 2016
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7B6A
 | | BK Polyomavirus VP1 pentamer core (residues 30-299) | | 分子名称: | CALCIUM ION, DIMETHYL SULFOXIDE, IODIDE ION, ... | | 著者 | Osipov, E.M, Munawar, A, Beelen, S, Strelkov, S.V. | | 登録日 | 2020-12-07 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | Discovery of novel druggable pockets on polyomavirus VP1 through crystallographic fragment-based screening to develop capsid assembly inhibitors.
Rsc Chem Biol, 3, 2022
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7A01
 | | The Halastavi arva virus intergenic region IRES promotes translation by the simplest possible initiation mechanism | | 分子名称: | 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES21, ... | | 著者 | Abaeva, I, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T.V, Hashem, Y, Hellen, C.U.T. | | 登録日 | 2020-08-05 | | 公開日 | 2020-12-30 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
Cell Rep, 33, 2020
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8WT1
 | | Crystal structure of S9 carboxypeptidase from Geobacillus sterothermophilus | | 分子名称: | ALANINE, CITRATE ANION, GLYCEROL, ... | | 著者 | Chandravanshi, K, Kumar, A, Sen, C, Singh, R, Bhange, G.B, Makde, R.D. | | 登録日 | 2023-10-17 | | 公開日 | 2024-03-13 | | 最終更新日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure and solution scattering of Geobacillus stearothermophilus S9 peptidase reveal structural adaptations for carboxypeptidase activity.
Febs Lett., 598, 2024
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5JH0
 | | Crystal structure of the mitochondrial DNA packaging protein Abf2p in complex with DNA at 2.18 Angstrom resolution | | 分子名称: | ARS-binding factor 2, mitochondrial, DNA (5'-D(*AP*AP*TP*AP*AP*TP*AP*AP*AP*TP*TP*AP*TP*AP*TP*AP*AP*TP*AP*TP*AP*A)-3'), ... | | 著者 | Chakraborty, A, Lyonnais, S, Sola, M. | | 登録日 | 2016-04-20 | | 公開日 | 2017-02-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | DNA structure directs positioning of the mitochondrial genome packaging protein Abf2p.
Nucleic Acids Res., 45, 2017
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6PAJ
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7ZNR
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7ZNS
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6ZOK
 | | SARS-CoV-2-Nsp1-40S complex, focused on body | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | | 著者 | Schubert, K, Karousis, E.D, Jomaa, A, Scaiola, A, Echeverria, B, Gurzeler, L.-A, Leibundgut, M, Thiel, V, Muehlemann, O, Ban, N. | | 登録日 | 2020-07-07 | | 公開日 | 2020-07-29 | | 最終更新日 | 2021-02-10 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation.
Nat.Struct.Mol.Biol., 27, 2020
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5FRA
 | | CBM40_CPF0721-6'SL | | 分子名称: | ACETATE ION, N-acetyl-alpha-neuraminic acid, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose, ... | | 著者 | Ribeiro, J.P, Pau, W, Pifferi, C, Renaudet, O, Varrot, A, Mahal, L.K, Imberty, A. | | 登録日 | 2015-12-16 | | 公開日 | 2016-07-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Characterization of a High-Affinity Sialic Acid-Specific Cbm40 from Clostridium Perfringens and Engineering of a Divalent Form.
Biochem.J., 473, 2016
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