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2D3U
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BU of 2d3u by Molmil
X-ray crystal structure of hepatitis C virus RNA dependent RNA polymerase in complex with non-nucleoside analogue inhibitor
分子名称: 5-(4-CYANOPHENYL)-3-{[(2-METHYLPHENYL)SULFONYL]AMINO}THIOPHENE-2-CARBOXYLIC ACID, polyprotein
著者Biswal, B.K, Wang, M, Cherney, M.M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Bedard, J, James, M.N.G.
登録日2005-10-02
公開日2006-08-01
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Non-nucleoside Inhibitors Binding to Hepatitis C Virus NS5B Polymerase Reveal a Novel Mechanism of Inhibition
J.Mol.Biol., 361, 2006
2FFA
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BU of 2ffa by Molmil
Crystal structure of ABC-ATPase H662A of the ABC-transporter HlyB in complex with ADP
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Alpha-hemolysin translocation ATP-binding protein hlyB
著者Zaitseva, J, Oswald, C, Jumpertz, T, Jenewein, S, Holland, I.B, Schmitt, L.
登録日2005-12-19
公開日2006-08-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A structural analysis of asymmetry required for catalytic activity of an ABC-ATPase domain dimer.
Embo J., 25, 2006
2FK7
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BU of 2fk7 by Molmil
Crystal structure of Hma (MmaA4) from Mycobacterium tuberculosis, apo-form
分子名称: methoxy mycolic acid synthase 4
著者Boissier, F, Guillet, V, Mourey, L.
登録日2006-01-04
公開日2006-01-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Further insight into S-adenosylmethionine-dependent methyltransferases: structural characterization of Hma, an enzyme essential for the biosynthesis of oxygenated mycolic acids in Mycobacterium tuberculosis.
J.Biol.Chem., 281, 2006
2ESR
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BU of 2esr by Molmil
conserved hypothetical protein- streptococcus pyogenes
分子名称: Methyltransferase, alpha-D-glucopyranose
著者Jiang, J, Min, T, Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2005-10-26
公開日2006-02-07
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of hypothetical protein of Streptococcus Pygenes
To be Published
2FLN
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BU of 2fln by Molmil
binary complex of catalytic core of human DNA polymerase iota with DNA (template A)
分子名称: DNA polymerase iota, DNA primer strand, DNA template strand
著者Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K.
登録日2006-01-06
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site.
Structure, 14, 2006
2EWA
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BU of 2ewa by Molmil
Dual binding mode of pyridinylimidazole to MAP kinase p38
分子名称: 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE, Mitogen-activated protein kinase 14
著者Delarbre, L, Pouzieux, S, Guilloteau, J.-P, Michot, N.
登録日2005-11-02
公開日2006-08-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献NMR characterization of kinase p38 dynamics in free and ligand-bound forms.
Angew.Chem.Int.Ed.Engl., 45, 2006
2EWO
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BU of 2ewo by Molmil
X-ray structure of putative agmatine deiminase Q8DW17, Northeast Structural Genomics target SmR6.
分子名称: Putative agmatine deiminase
著者Kuzin, A.P, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2005-11-04
公開日2005-12-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献X-ray structure of putative agmatine deiminase Q8DW17, Northeast Structural Genomics target SmR6.
TO BE PUBLISHED
2EX0
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BU of 2ex0 by Molmil
Crystal structure of multifunctional sialyltransferase from Pasteurella Multocida
分子名称: a2,3-sialyltransferase, a2,6-sialyltransferase
著者Ni, L, Sun, M, Chen, X, Fisher, A.J.
登録日2005-11-07
公開日2006-02-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Cytidine 5'-Monophosphate (CMP)-Induced Structural Changes in a Multifunctional Sialyltransferase from Pasteurella multocida
Biochemistry, 45, 2006
2F3O
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Crystal Structure of a glycyl radical enzyme from Archaeoglobus fulgidus
分子名称: GLYCEROL, TRIETHYLENE GLYCOL, pyruvate formate-lyase 2
著者Lehtio, L, Goldman, A.
登録日2005-11-22
公開日2006-03-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of a glycyl radical enzyme from Archaeoglobus fulgidus
J.Mol.Biol., 357, 2006
2F02
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Crystal Structure of LacC from Enterococcus Faecalis in complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, tagatose-6-phosphate kinase
著者Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2005-11-10
公開日2005-11-22
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of LacC from Enterococcus Faecalis in complex with ATP
To be Published
2FFD
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Fibrinogen Fragment D with "A" knob peptide mimic GPRVVE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E Chain, ...
著者Betts, L.
登録日2005-12-19
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献The structure of fibrinogen fragment D with the 'A' knob peptide GPRVVE.
THROMB.HAEMOST., 4, 2006
2F1Z
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BU of 2f1z by Molmil
Crystal structure of HAUSP
分子名称: Ubiquitin carboxyl-terminal hydrolase 7
著者Hu, M, Gu, L, Jeffrey, P.D, Shi, Y.
登録日2005-11-15
公開日2006-02-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway.
Plos Biol., 4, 2006
2F3V
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BU of 2f3v by Molmil
Solution structure of 1-110 fragment of staphylococcal nuclease with V66W mutation
分子名称: Thermonuclease
著者Liu, D, Xie, T, Feng, Y, Shan, L, Ye, K, Wang, J.
登録日2005-11-22
公開日2006-12-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Folding stability and cooperativity of the three forms of 1-110 residues fragment of staphylococcal nuclease
Biophys.J., 92, 2007
2F9C
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BU of 2f9c by Molmil
Crystal structure of YDCK from Salmonella cholerae. NESG target SCR6
分子名称: CESIUM ION, Hypothetical protein YDCK
著者Benach, J, Chen, Y, Vorobiev, S.M, Seetharaman, J, Janjua, H, Cooper, B, Acton, X.T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2005-12-05
公開日2005-12-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of YDCK from Salmonella cholerae NESG target SCR6.
To be Published
2EU3
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BU of 2eu3 by Molmil
Human Carbonic anhydrase II in complex with novel inhibitors
分子名称: 1-(5-AMINO-1,3,4-THIADIAZOL-2-YL)-1,1-DIFLUOROMETHANESULFONAMIDE, Carbonic anhydrase 2, ZINC ION
著者Fisher, S.Z, Govindasamy, L, Boyle, N, Agbandje-McKenna, M, Silverman, D.N, Blackburn, G.M, McKenna, R.
登録日2005-10-28
公開日2006-07-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献X-ray crystallographic studies reveal that the incorporation of spacer groups in carbonic anhydrase inhibitors causes alternate binding modes.
Acta Crystallogr.,Sect.F, 62, 2006
2FAZ
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BU of 2faz by Molmil
Ubiquitin-Like Domain of Human Nuclear Zinc Finger Protein NP95
分子名称: Ubiquitin-like containing PHD and RING finger domains protein 1
著者Walker, J.R, Wybenga-Groot, L, Doherty, R.S, Finerty Jr, P.J, Newman, E, Mackenzie, F.M, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2005-12-08
公開日2005-12-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Ubiquitin-Like Domain of Human Nuclear Zinc Finger Protein NP95
To be Published
2EUK
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Crystal Structure of Human Glycolipid Transfer Protein complexed with 24:1 Galactosylceramide
分子名称: (15E)-TETRACOS-15-ENOIC ACID, Glycolipid transfer protein, N-OCTANE, ...
著者Malinina, L, Malakhova, M.L, Kanack, A.T, Abagyan, R, Brown, R.E, Patel, D.J.
登録日2005-10-28
公開日2006-11-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The liganding of glycolipid transfer protein is controlled by glycolipid acyl structure.
Plos Biol., 4, 2006
2EVT
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BU of 2evt by Molmil
Crystal structure of D48V mutant of human Glycolipid Transfer Protein
分子名称: Glycolipid transfer protein, HEXANE
著者Malinina, L, Malakhova, M.L, Teplov, A, Brown, R.E, Patel, D.J.
登録日2005-10-31
公開日2005-11-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The liganding of glycolipid transfer protein is controlled by glycolipid acyl structure.
Plos Biol., 4, 2006
2FEL
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3-carboxy-cis,cis-muconate lactonizing enzyme from Agrobacterium radiobacter S2
分子名称: 3-carboxy-cis,cis-muconate lactonizing enzyme, CHLORIDE ION, SULFATE ION
著者Lehtio, L, Goldman, A.
登録日2005-12-16
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and function of the 3-carboxy-cis,cis-muconate lactonizing enzyme from the protocatechuate degradative pathway of Agrobacterium radiobacter S2.
Febs J., 273, 2006
2F1Y
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BU of 2f1y by Molmil
Crystal structure of the TRAF-like domain of HAUSP/USP7 bound to a MDM2 peptide
分子名称: HAUSP/USP7
著者Hu, M, Gu, L, Jeffrey, P.D, Shi, Y.
登録日2005-11-15
公開日2006-02-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway.
Plos Biol., 4, 2006
2F4O
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BU of 2f4o by Molmil
The Mouse PNGase-HR23 Complex Reveals a Complete Remodulation of the Protein-Protein Interface Compared to its Yeast Orthologs
分子名称: CHLORIDE ION, PHQ-VAL-ALA-ASP-CF0, XP-C repair complementing complex 58 kDa protein, ...
著者Zhao, G, Zhou, X, Wang, L, Kisker, C, Lennarz, W.J, Schindelin, H.
登録日2005-11-23
公開日2006-03-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways.
J.Biol.Chem., 281, 2006
2F6K
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Crystal Structure of Amidohydrorolase II; Northeast Structural Genomics Target LpR24
分子名称: MANGANESE (II) ION, metal-dependent hydrolase
著者Das, K, Xiao, R, Acton, T, Ma, L, Arnold, E, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2005-11-29
公開日2006-01-10
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of ACMDS from Lactobacillus plantarum
To be Published
2F7K
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Crystal Structure of Human Pyridoxal Kinase
分子名称: Pyridoxal kinase
著者Jiang, T, Cao, P, Gong, Y, Tang, L.
登録日2005-12-01
公開日2006-06-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of human pyridoxal kinase
J.Struct.Biol., 154, 2006
2FFK
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Solution structure of the complex between poxvirus-encoded CC chemokine inhibitor vCCI and human MIP-1beta, minimized average structure
分子名称: Small inducible cytokine A4, rabbitpox encoded CC chemokine inhibitor
著者Zhang, L.
登録日2005-12-19
公開日2006-08-22
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Solution structure of the complex between poxvirus-encoded CC chemokine inhibitor vCCI and human MIP-1beta.
Proc.Natl.Acad.Sci.Usa, 103, 2006
6KVW
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The complex structure of EanB/C339A/C370A and hercynine
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Wu, L, Liu, P.H, Zhou, J.H.
登録日2019-09-05
公開日2020-09-09
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The complex structure of EanB/C339A/C370A and hercynine
To Be Published

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