Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2EWA

Dual binding mode of pyridinylimidazole to MAP kinase p38

Summary for 2EWA
Entry DOI10.2210/pdb2ewa/pdb
DescriptorMitogen-activated protein kinase 14, 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE (3 entities in total)
Functional Keywordsmap kinase, dfg out, transferase
Biological sourceMus musculus (house mouse)
Cellular locationCytoplasm: P47811
Total number of polymer chains1
Total formula weight43760.79
Authors
Delarbre, L.,Pouzieux, S.,Guilloteau, J.-P.,Michot, N. (deposition date: 2005-11-02, release date: 2006-08-01, Last modification date: 2024-02-14)
Primary citationVogtherr, M.,Saxena, K.,Hoelder, S.,Grimme, S.,Betz, M.,Schieborr, U.,Pescatore, B.,Robin, M.,Delarbre, L.,Langer, T.,Wendt, K.U.,Schwalbe, H.
NMR characterization of kinase p38 dynamics in free and ligand-bound forms.
Angew.Chem.Int.Ed.Engl., 45:993-997, 2006
Cited by
PubMed: 16374788
DOI: 10.1002/anie.200502770
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon