3RDZ
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3RDY
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7ESX
| Crystal structure of Wolbachia cytoplasmic incompatibility factor CidA from wPip | 分子名称: | Bacteria factor 1 | 著者 | Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T. | 登録日 | 2021-05-12 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors. Proc.Natl.Acad.Sci.USA, 118, 2021
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7ESY
| Crystal structure of the complex formed by Wolbachia cytoplasmic incompatibility factors CidA and CidBND1-ND2 from wPip | 分子名称: | Bacteria factor 1, CALCIUM ION, ULP_PROTEASE domain-containing protein | 著者 | Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T. | 登録日 | 2021-05-12 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.297 Å) | 主引用文献 | Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors. Proc.Natl.Acad.Sci.USA, 118, 2021
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7ESZ
| Crystal structure of the complex formed by Wolbachia cytoplasmic incompatibility factors CinA and CinB with Mn2+ from wPip | 分子名称: | BACTERIA FACTOR A, BACTERIA FACTOR B, MANGANESE (II) ION | 著者 | Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T. | 登録日 | 2021-05-12 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.476 Å) | 主引用文献 | Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors. Proc.Natl.Acad.Sci.USA, 118, 2021
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7ET0
| Crystal structure of the complex formed by Wolbachia cytoplasmic incompatibility factors CinA and CinB from wPip | 分子名称: | Bacteria factor A, Bacteria factor B | 著者 | Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T. | 登録日 | 2021-05-12 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors. Proc.Natl.Acad.Sci.USA, 118, 2021
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7BY7
| Bacteriophage SPO1 protein Gp46 | 分子名称: | Putative gene 46 protein | 著者 | Liu, B, Zhang, P. | 登録日 | 2020-04-22 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Bacteriophage protein Gp46 is a cross-species inhibitor of nucleoid-associated HU proteins Proc.Natl.Acad.Sci.USA, 119, 2022
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6NM5
| F-pilus/MS2 Maturation protein complex | 分子名称: | (2R)-2,3-dihydroxypropyl ethyl hydrogen (S)-phosphate, Maturation protein, Type IV conjugative transfer system pilin TraA | 著者 | Meng, R, Chang, J, Zhang, J. | 登録日 | 2019-01-10 | 公開日 | 2019-07-24 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | Structural basis for the adsorption of a single-stranded RNA bacteriophage. Nat Commun, 10, 2019
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7CKF
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3NBP
| HIV-1 reverse transcriptase with aminopyrimidine inhibitor 2 | 分子名称: | 4-(4-{[4-(4-cyano-2,6-dimethylphenoxy)pyrimidin-2-yl]amino}piperidin-1-yl)benzenesulfonamide, MANGANESE (II) ION, Reverse transcriptase/ribonuclease H, ... | 著者 | Harris, S.F, Villasenor, A.G. | 登録日 | 2010-06-03 | 公開日 | 2010-08-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Discovery of piperidin-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-benzyl derivatives with broad potency against resistant mutant viruses. Bioorg.Med.Chem.Lett., 20, 2010
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7DWS
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6V9C
| Crystal structure of FGFR4 kinase domain in complex with covalent inhibitor | 分子名称: | Fibroblast growth factor receptor 4, N-[(3R,4S)-4-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}oxolan-3-yl]prop-2-enamide, SULFATE ION | 著者 | Liu, J, Liu, H. | 登録日 | 2019-12-13 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of Selective, Covalent FGFR4 Inhibitors with Antitumor Activity in Models of Hepatocellular Carcinoma. Acs Med.Chem.Lett., 11, 2020
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6V4J
| Structure of TrkH-TrkA in complex with ATP | 分子名称: | Potassium uptake protein TrkA, Trk system potassium uptake protein TrkH | 著者 | Zhou, M, Zhang, H. | 登録日 | 2019-11-27 | 公開日 | 2020-02-12 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential. Nat Commun, 11, 2020
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6V4L
| Structure of TrkH-TrkA in complex with ATPgammaS | 分子名称: | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Potassium uptake protein TrkA, Trk system potassium uptake protein TrkH | 著者 | Zhou, M, Zhang, H. | 登録日 | 2019-11-27 | 公開日 | 2020-02-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential. Nat Commun, 11, 2020
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6V4K
| Structure of TrkH-TrkA in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Potassium transporter peripheral membrane component, Trk system potassium uptake protein | 著者 | Zhou, M, Zhang, H. | 登録日 | 2019-11-27 | 公開日 | 2020-02-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.53004146 Å) | 主引用文献 | TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential. Nat Commun, 11, 2020
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4NSD
| Crystal Structure of CBARA1 in the Ca2+ Binding Form | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Wang, L, Yang, X, Li, S, Shen, Y. | 登録日 | 2013-11-28 | 公開日 | 2014-02-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake. Embo J., 33, 2014
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4NSC
| Crystal Structure of CBARA1 in the Apo-form | 分子名称: | Calcium uptake protein 1, mitochondrial | 著者 | Wang, L, Yang, X, Li, S, Shen, Y. | 登録日 | 2013-11-28 | 公開日 | 2014-02-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake. Embo J., 33, 2014
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5JW2
| Crystal structure of mithramycin analogue MTM SA-Phe in complex with a 10-mer DNA AGGGATCCCT | 分子名称: | DNA (5'-D(*AP*GP*GP*GP*AP*TP*CP*CP*CP*T)-3'), Plicamycin, mithramycin analogue MTM SA-Phe, ... | 著者 | Hou, C, Rohr, J, Tsodikov, O.V. | 登録日 | 2016-05-11 | 公開日 | 2016-09-14 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1. Nucleic Acids Res., 44, 2016
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5JVT
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5K4Z
| M. thermoresistible IMPDH in complex with IMP and Compound 6 | 分子名称: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase, ~{N}-(4-fluorophenyl)-4-(2~{H}-indazol-6-ylsulfamoyl)-3,5-dimethyl-1~{H}-pyrrole-2-carboxamide | 著者 | Pacitto, A, Ascher, D.B, Blundell, T.L. | 登録日 | 2016-05-22 | 公開日 | 2016-10-19 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis. ACS Infect Dis, 3, 2017
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5JVW
| Crystal structure of mithramycin analogue MTM SA-Trp in complex with a 10-mer DNA AGAGGCCTCT. | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*GP*CP*CP*TP*CP*T)-3'), Plicamycin, mithramycin analogue MTM SA-Trp, ... | 著者 | Hou, C, Rohr, J, Tsodikov, O.V. | 登録日 | 2016-05-11 | 公開日 | 2016-09-14 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1. Nucleic Acids Res., 44, 2016
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5K4X
| M. thermoresistible IMPDH in complex with IMP and Compound 1 | 分子名称: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase, ~{N}-(2~{H}-indazol-6-yl)-3,5-dimethyl-1~{H}-pyrazole-4-sulfonamide | 著者 | Pacitto, A, Ascher, D.B, Blundell, T.L. | 登録日 | 2016-05-22 | 公開日 | 2016-10-19 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis. ACS Infect Dis, 3, 2017
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5J1E
| Crystal Structure of a Hydroxypyridone Carboxylic Acid Active-Site RNase H Inhibitor in Complex with HIV Reverse Transcriptase | 分子名称: | 5-hydroxy-4-oxo-1-[(4'-sulfamoyl[1,1'-biphenyl]-4-yl)methyl]-1,4-dihydropyridine-3-carboxylic acid, HIV-1 REVERSE TRANSCRIPTASE P51 DOMAIN, HIV-1 REVERSE TRANSCRIPTASE P66 DOMAIN, ... | 著者 | Kirby, K.A, Sarafianos, S.G. | 登録日 | 2016-03-29 | 公開日 | 2016-06-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Design, Synthesis, and Biological Evaluations of Hydroxypyridonecarboxylic Acids as Inhibitors of HIV Reverse Transcriptase Associated RNase H. J.Med.Chem., 59, 2016
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8FHS
| Human L-type voltage-gated calcium channel Cav1.2 in the presence of amiodarone and sofosbuvir at 3.3 Angstrom resolution | 分子名称: | (2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Gao, S, Yao, X, Yan, N. | 登録日 | 2022-12-15 | 公開日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for human Ca v 1.2 inhibition by multiple drugs and the neurotoxin calciseptine. Cell, 186, 2023
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5JW0
| Crystal structure of mithramycin analogue MTM SA-Phe in complex with a 10-mer DNA AGGGTACCCT | 分子名称: | DNA (5'-D(P*AP*GP*GP*GP*TP*AP*CP*CP*CP*T)-3'), Plicamycin, mithramycin analogue MTM SA-Phe, ... | 著者 | Hou, C, Rohr, J, Tsodikov, O.V. | 登録日 | 2016-05-11 | 公開日 | 2016-09-14 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1. Nucleic Acids Res., 44, 2016
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