5I82
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![BU of 5i82 by Molmil](/molmil-images/mine/5i82) | First Crystal Structure of E.coli Based Recombinant Diphtheria Toxin Mutant CRM197 | 分子名称: | Diphtheria toxin, GLYCEROL, SULFATE ION | 著者 | Minasov, G, Shuvalova, L, Mishra, R.P.N, Goel, A, Dubrovska, I, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-02-18 | 公開日 | 2016-03-02 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural and immunological characterization of E. coli derived recombinant CRM 197 protein used as carrier in conjugate vaccines. Biosci.Rep., 38, 2018
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5HM3
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![BU of 5hm3 by Molmil](/molmil-images/mine/5hm3) | 2.25 Angstrom Resolution Crystal Structure of Long-chain-fatty-acid-AMP Ligase FadD32 from Mycobacterium tuberculosis in complex with Inhibitor 5'-O-[(11-phenoxyundecanoyl)sulfamoyl]adenosine | 分子名称: | 5'-O-[(11-phenoxyundecanoyl)sulfamoyl]adenosine, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Minasov, G, Warwrzak, Z, Kuhn, M.L, Shuvalova, L, Flores, K.J, Wilson, D.J, Grimes, K.D, Aldrich, C.C, Anderson, W.A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-01-15 | 公開日 | 2016-08-03 | 最終更新日 | 2016-09-07 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure of the Essential Mtb FadD32 Enzyme: A Promising Drug Target for Treating Tuberculosis. Acs Infect Dis., 2, 2016
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5I1T
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![BU of 5i1t by Molmil](/molmil-images/mine/5i1t) | 2.6 Angstrom Resolution Crystal Structure of Stage II Sporulation Protein D (SpoIID) from Clostridium difficile in Complex with Triacetylchitotriose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | 著者 | Nocadello, S, Minasov, G, Shuvalova, L, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-02-05 | 公開日 | 2016-05-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structures of the SpoIID Lytic Transglycosylases Essential for Bacterial Sporulation. J.Biol.Chem., 291, 2016
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4GFP
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![BU of 4gfp by Molmil](/molmil-images/mine/4gfp) | 2.7 Angstrom resolution structure of 3-phosphoshikimate 1-carboxyvinyltransferase (AroA) from Coxiella burnetii in a second conformational state | 分子名称: | 3-phosphoshikimate 1-carboxyvinyltransferase, BETA-MERCAPTOETHANOL | 著者 | Light, S.H, Minasov, G, Krishna, S.N, Shuvalova, L, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2012-08-03 | 公開日 | 2012-08-15 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | 2.7 Angstrom resolution structure of 3-phosphoshikimate 1-carboxyvinyltransferase (AroA) from Coxiella burnetii in second conformational state TO BE PUBLISHED
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4GL0
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![BU of 4gl0 by Molmil](/molmil-images/mine/4gl0) | Putative spermidine/putrescine ABC transporter from Listeria monocytogenes | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Lmo0810 protein, ... | 著者 | Osipiuk, J, Zhou, M, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2012-08-13 | 公開日 | 2012-08-22 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Putative spermidine/putrescine ABC transporter from Listeria monocytogenes To be Published
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4PWZ
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![BU of 4pwz by Molmil](/molmil-images/mine/4pwz) | Crystal structure of TolB protein from Yersinia pestis CO92 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Maltseva, N, Kim, Y, Osipiuk, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2014-03-21 | 公開日 | 2014-04-02 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.732 Å) | 主引用文献 | Crystal structure of TolB protein from Yersinia pestis CO92 To be Published
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7S6P
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![BU of 7s6p by Molmil](/molmil-images/mine/7s6p) | The crystal structure of human ISG15 | 分子名称: | Ubiquitin-like protein ISG15 | 著者 | Osipiuk, J, Tesar, C, Jedrzejczak, R, Endres, M, Wydorski, P, Joachimiak, L, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-09-14 | 公開日 | 2021-09-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin. Nat Commun, 14, 2023
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7S14
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![BU of 7s14 by Molmil](/molmil-images/mine/7s14) | Crystal structure of putative NAD(P)H-flavin oxidoreductase from Haemophilus influenzae 86-028NP | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Kim, Y, Maltseva, N, Endres, M, Crofts, T, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-08-31 | 公開日 | 2021-10-06 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Functional and Structural Characterization of Diverse NfsB Chloramphenicol Reductase Enzymes from Human Pathogens. Microbiol Spectr, 10, 2022
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4PV4
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![BU of 4pv4 by Molmil](/molmil-images/mine/4pv4) | Proline aminopeptidase P II from Yersinia pestis | 分子名称: | 1,2-ETHANEDIOL, HEXAETHYLENE GLYCOL, MAGNESIUM ION, ... | 著者 | Osipiuk, J, Maltseva, N, Shatsman, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2014-03-14 | 公開日 | 2014-04-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Proline aminopeptidase P II from Yersinia pestis To be Published
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4PPZ
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![BU of 4ppz by Molmil](/molmil-images/mine/4ppz) | Crystal structure of zinc-bound succinyl-diaminopimelate desuccinylase from Neisseria meningitidis MC58 | 分子名称: | PHOSPHATE ION, Succinyl-diaminopimelate desuccinylase, ZINC ION | 著者 | Nocek, B, Holz, R, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2014-02-27 | 公開日 | 2014-03-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril. Biochemistry, 54, 2015
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4GB7
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![BU of 4gb7 by Molmil](/molmil-images/mine/4gb7) | Putative 6-aminohexanoate-dimer hydrolase from Bacillus anthracis | 分子名称: | 1,2-ETHANEDIOL, 6-aminohexanoate-dimer hydrolase, NITRATE ION | 著者 | Osipiuk, J, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2012-07-26 | 公開日 | 2012-08-08 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Putative 6-aminohexanoate-dimer hydrolase from Bacillus anthracis. To be Published
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4FXS
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![BU of 4fxs by Molmil](/molmil-images/mine/4fxs) | Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae complexed with IMP and mycophenolic acid | 分子名称: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase, MYCOPHENOLIC ACID, ... | 著者 | Osipiuk, J, Maltseva, N, Makowska-Grzyska, M, Jedrzejczak, R, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2012-07-03 | 公開日 | 2012-07-25 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae complexed with IMP and mycophenolic acid. To be Published
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7RZP
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![BU of 7rzp by Molmil](/molmil-images/mine/7rzp) | Crystal structure of putative NAD(P)H-flavin oxidoreductase from Haemophilus influenzae R2866 | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, Dihydropteridine reductase, ... | 著者 | Maltseva, N, Kim, Y, Endres, M, Crofts, T, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-08-27 | 公開日 | 2021-09-29 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Functional and Structural Characterization of Diverse NfsB Chloramphenicol Reductase Enzymes from Human Pathogens. Microbiol Spectr, 10, 2022
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7RZL
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![BU of 7rzl by Molmil](/molmil-images/mine/7rzl) | Crystal structure of putative NAD(P)H-flavin oxidoreductase from Haemophilus influenzae R2846 in complex with 4-nitrophenol | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN MONONUCLEOTIDE, ... | 著者 | Maltseva, N, Kim, Y, Endres, M, Crofts, T, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-08-27 | 公開日 | 2021-09-29 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Functional and Structural Characterization of Diverse NfsB Chloramphenicol Reductase Enzymes from Human Pathogens. Microbiol Spectr, 10, 2022
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7S1A
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![BU of 7s1a by Molmil](/molmil-images/mine/7s1a) | Crystal structure of putative NAD(P)H-flavin oxidoreductase from Haemophilus influenzae Rd KW20 | 分子名称: | ACETIC ACID, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | 著者 | Maltseva, N, Kim, Y, Endres, M, Crofts, T, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-09-01 | 公開日 | 2021-10-06 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Functional and Structural Characterization of Diverse NfsB Chloramphenicol Reductase Enzymes from Human Pathogens. Microbiol Spectr, 10, 2022
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5HMN
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![BU of 5hmn by Molmil](/molmil-images/mine/5hmn) | Crystal structure of an aminoglycoside acetyltransferase HMB0005 from an uncultured soil metagenomic sample, unknown active site density modeled as polyethylene glycol | 分子名称: | AAC3-I, COENZYME A, TETRAETHYLENE GLYCOL | 著者 | Xu, Z, Stogios, P.J, Wawrzak, Z, Skarina, T, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-01-16 | 公開日 | 2016-02-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.018 Å) | 主引用文献 | Crystal structure of an aminoglycoside acetyltransferase HMB0005 from an uncultured soil metagenomic sample, unknown active site density modeled as polyethylene glycol To Be Published
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4GJ1
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![BU of 4gj1 by Molmil](/molmil-images/mine/4gj1) | Crystal structure of 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (hisA). | 分子名称: | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase | 著者 | Nocek, B, Gu, M, Kwon, K, Anderson, W.F, Joachimiak, A, CSGID, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2012-08-09 | 公開日 | 2012-08-22 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.152 Å) | 主引用文献 | Crystal structure of 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (hisA). To be Published
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5I4C
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![BU of 5i4c by Molmil](/molmil-images/mine/5i4c) | Crystal structure of non-phosphorylated receiver domain of the stress response regulator RcsB from Escherichia coli | 分子名称: | Transcriptional regulatory protein RcsB | 著者 | Filippova, E.V, Wawrzak, Z, Minasov, G, Ruan, J, Pshenychnyi, S, Wolfe, A.J, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-02-11 | 公開日 | 2016-10-12 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of nonphosphorylated receiver domain of the stress response regulator RcsB from Escherichia coli. Protein Sci., 25, 2016
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7RZC
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![BU of 7rzc by Molmil](/molmil-images/mine/7rzc) | Papain-Like Protease of SARS CoV-2 in complex with Jun9-84-3 inhibitor | 分子名称: | (1R)-N-[(1H-indol-3-yl)methyl]-N-methyl-1-(naphthalen-1-yl)ethan-1-amine, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | Osipiuk, J, Tesar, C, Endres, M, Wang, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-08-27 | 公開日 | 2021-09-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Papain-Like Protease of SARS CoV-2 in complex with Jun9-84-3 inhibitor To be Published
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7SDR
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![BU of 7sdr by Molmil](/molmil-images/mine/7sdr) | Papain-Like Protease of SARS CoV-2 in Complex with Jun9-72-2 Inhibitor | 分子名称: | 1,2-ETHANEDIOL, 4-({methyl[(1R)-1-(naphthalen-1-yl)ethyl]amino}methyl)phenol, CHLORIDE ION, ... | 著者 | Osipiuk, J, Tesar, C, Endres, M, Wang, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-09-29 | 公開日 | 2021-10-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Papain-Like Protease of SARS CoV-2 in Complex with Jun9-72-2 Inhibitor To be Published
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5HOP
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![BU of 5hop by Molmil](/molmil-images/mine/5hop) | 1.65 Angstrom resolution crystal structure of lmo0182 (residues 1-245) from Listeria monocytogenes EGD-e | 分子名称: | ACETATE ION, Lmo0182 protein | 著者 | Halavaty, A.S, Light, S.H, Minasov, G, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-01-19 | 公開日 | 2017-02-01 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Transferase Versus Hydrolase: The Role of Conformational Flexibility in Reaction Specificity. Structure, 25, 2017
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3M5W
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![BU of 3m5w by Molmil](/molmil-images/mine/3m5w) | Crystal Structure of Tryptophanyl-tRNA Synthetase from Campylobacter jejuni | 分子名称: | GLYCEROL, SULFATE ION, Tryptophanyl-tRNA synthetase | 著者 | Kim, Y, Zhou, M, Hasseman, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-03-14 | 公開日 | 2010-03-31 | 最終更新日 | 2014-10-01 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Crystal Structure of Tryptophanyl-tRNA Synthetase from Campylobacter jejuni To be Published, 2010
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5HXM
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![BU of 5hxm by Molmil](/molmil-images/mine/5hxm) | Cycloalternan-forming enzyme from Listeria monocytogenes in complex with panose | 分子名称: | Alpha-xylosidase, CALCIUM ION, CHLORIDE ION, ... | 著者 | Halavaty, A.S, Light, S.H, Minasov, G, Winsor, J, Grimshaw, S, Shuvalova, L, Peterson, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-01-31 | 公開日 | 2017-01-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Transferase Versus Hydrolase: The Role of Conformational Flexibility in Reaction Specificity. Structure, 25, 2017
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5I0E
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![BU of 5i0e by Molmil](/molmil-images/mine/5i0e) | Cycloalternan-degrading enzyme from Trueperella pyogenes in complex with isomaltose | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Glycoside hydrolase family 31, ... | 著者 | Light, S.H, Minasov, G, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-02-03 | 公開日 | 2016-12-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Transferase Versus Hydrolase: The Role of Conformational Flexibility in Reaction Specificity. Structure, 25, 2017
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5INT
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![BU of 5int by Molmil](/molmil-images/mine/5int) | Crystal structure of the C-terminal Domain of Coenzyme A biosynthesis bifunctional protein CoaBC | 分子名称: | Phosphopantothenate--cysteine ligase | 著者 | Nocek, B, Zhou, M, Grimshaw, S, Kim, Y, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-03-07 | 公開日 | 2016-04-06 | 最終更新日 | 2018-09-19 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structure of the C-terminal Domain of Coenzyme A biosynthesis bifunctional protein CoaBC To Be Published
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