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2B3U
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Human Spermine spermidine acetyltransferase K26R mutant
分子名称: Diamine acetyltransferase 1, SULFATE ION
著者Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2005-09-21
公開日2006-01-17
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target.
Proc.Natl.Acad.Sci.USA, 103, 2006
2B3V
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Spermine spermidine acetyltransferase in complex with acetylcoa, K26R mutant
分子名称: ACETYL COENZYME *A, Diamine acetyltransferase 1
著者Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2005-09-21
公開日2006-01-17
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target.
Proc.Natl.Acad.Sci.USA, 103, 2006
1V1R
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CROSSTALK BETWEEN COFACTOR BINDING AND THE PHOSPHORYLATION LOOP CONFORMATION IN THE BCKD MACHINE
分子名称: 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, CHLORIDE ION, ...
著者Li, J, Wynn, R.M, Machius, M, Chuang, J.L, Karthikeyan, S, Tomchick, D.R, Chuang, D.T.
登録日2004-04-22
公開日2004-06-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cross-Talk between Thiamin Diphosphate Binding and Phosphorylation Loop Conformation in Human Branched-Chain {Alpha}-Keto Acid Decarboxylase/Dehydrogenase
J.Biol.Chem., 279, 2004
2KOI
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Refined solution structure of a cyanobacterial phytochrome GAF domain in the red light-absorbing ground state
分子名称: PHYCOCYANOBILIN, Sensor protein
著者Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Vierstra, R.D, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG)
登録日2009-09-22
公開日2009-11-03
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural basis for the photoconversion of a phytochrome to the activated Pfr form
Nature, 463, 2010
5ORE
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Structure of the periplasmic binding protein (PBP) OccJ from agrobacterium tumefaciens B6
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Octopine-binding periplasmic protein
著者Vigouroux, A, Morera, S.
登録日2017-08-16
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis for high specificity of octopine binding in the plant pathogen Agrobacterium tumefaciens.
Sci Rep, 7, 2017
1V16
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CROSSTALK BETWEEN COFACTOR BINDING AND THE PHOSPHORYLATION LOOP CONFORMATION IN THE BCKD MACHINE
分子名称: 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, BENZAMIDINE, ...
著者Li, J, Wynn, R.M, Machius, M, Chuang, J.L, Karthikeyan, S, Tomchick, D.R, Chuang, D.T.
登録日2004-04-07
公開日2004-06-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cross-Talk between Thiamin Diphosphate Binding and Phosphorylation Loop Conformation in Human Branched-Chain {Alpha}-Keto Acid Decarboxylase/Dehydrogenase
J.Biol.Chem., 279, 2004
2KQE
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Second PBZ domain of human APLF protein in complex with ribofuranosyladenosine
分子名称: ADENOSINE, Aprataxin and PNK-like factor, ZINC ION, ...
著者Neuhaus, D, Eustermann, S, Brockmann, C, Yang, J.
登録日2009-11-04
公開日2010-01-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose).
Nat.Struct.Mol.Biol., 17, 2010
4NKB
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BU of 4nkb by Molmil
Crystal Structure of the cryptic polo box (CPB)of ZYG-1
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, ...
著者Shimanovskaya, E, Dong, G.
登録日2013-11-12
公開日2014-08-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the C. elegans ZYG-1 Cryptic Polo Box Suggests a Conserved Mechanism for Centriolar Docking of Plk4 Kinases.
Structure, 22, 2014
1NYJ
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The closed state structure of M2 protein H+ channel by solid state NMR spectroscopy
分子名称: Matrix protein M2
著者Nishimura, K, Kim, S, Zhang, L, Cross, T.A.
登録日2003-02-12
公開日2003-03-25
最終更新日2024-05-22
実験手法SOLID-STATE NMR
主引用文献The closed state of a H+ channel helical bundle combining precise orientational and distance restraints from solid state NMR
Biochemistry, 41, 2002
2XR5
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Crystal structure of the complex of the carbohydrate recognition domain of human DC-SIGN with pseudo dimannoside mimic.
分子名称: CALCIUM ION, CD209 ANTIGEN, CHLORIDE ION, ...
著者Thepaut, M, Suitkeviciute, I, Sattin, S, Reina, J, Bernardi, A, Fieschi, F.
登録日2010-09-10
公開日2011-10-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Structure of a Glycomimetic Ligand in the Carbohydrate Recognition Domain of C-Type Lectin Dc-Sign. Structural Requirements for Selectivity and Ligand Design.
J.Am.Chem.Soc., 135, 2013
1GOL
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BU of 1gol by Molmil
COORDINATES OF RAT MAP KINASE ERK2 WITH AN ARGININE MUTATION AT POSITION 52
分子名称: ADENOSINE-5'-TRIPHOSPHATE, EXTRACELLULAR REGULATED KINASE 2, MAGNESIUM ION
著者Harkins, P.C, Zhang, F, Goldsmith, E.J.
登録日1996-01-23
公開日1997-03-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mutation of position 52 in ERK2 creates a nonproductive binding mode for adenosine 5'-triphosphate.
Biochemistry, 35, 1996
5VD6
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Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with bisubstrate analog 6
分子名称: (3R,5S,9R,23S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14-dioxo-23-({[(phenylacetyl)amino]acetyl}amino)-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatetracosan-24-oic acid 3,5-dioxide (non-preferred name), SULFATE ION, acetyltransferase PA4794
著者Majorek, K.A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2017-04-01
公開日2017-07-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases.
FEBS Lett., 591, 2017
2L31
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Human PARP-1 zinc finger 2
分子名称: Poly [ADP-ribose] polymerase 1, ZINC ION
著者Neuhaus, D, Eustermann, S, Yang, J, Videler, H.
登録日2010-08-30
公開日2011-02-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The DNA-binding domain of human PARP-1 interacts with DNA single-strand breaks as a monomer through its second zinc finger.
J.Mol.Biol., 407, 2011
2L30
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Human PARP-1 zinc finger 1
分子名称: Poly [ADP-ribose] polymerase 1, ZINC ION
著者Neuhaus, D, Eustermann, S, Yang, J, Videler, H.
登録日2010-08-30
公開日2011-02-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The DNA-binding domain of human PARP-1 interacts with DNA single-strand breaks as a monomer through its second zinc finger.
J.Mol.Biol., 407, 2011
2LB5
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Refined Structural Basis for the Photoconversion of A Phytochrome to the Activated FAR-RED LIGHT-ABSORBING Form
分子名称: PHYCOCYANOBILIN, Sensor histidine kinase
著者Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Vierstra, R.D, Markley, J.L.
登録日2011-03-23
公開日2011-06-29
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural basis for the photoconversion of a phytochrome to the activated Pfr form.
Nature, 463, 2010
2F1G
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BU of 2f1g by Molmil
Cathepsin S in complex with non-covalent 2-(Benzoxazol-2-ylamino)-acetamide
分子名称: Cathepsin S, GLYCEROL, N~2~-1,3-BENZOXAZOL-2-YL-3-CYCLOHEXYL-N-{2-[(4-METHOXYPHENYL)AMINO]ETHYL}-L-ALANINAMIDE
著者Spraggon, G, Hornsby, M, Lesley, S.A, Tully, D.C, Harris, J.L, Karenewsky, D.S, Kulathila, R, Clark, K.
登録日2005-11-14
公開日2006-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Synthesis and evaluation of arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 3: Heterocyclic P3.
Bioorg.Med.Chem.Lett., 16, 2006
2K0A
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BU of 2k0a by Molmil
1H, 15N and 13C chemical shift assignments for Rds3 protein
分子名称: Pre-mRNA-splicing factor RDS3, ZINC ION
著者Loening, N, van Roon, A, Yang, J, Nagai, K, Neuhaus, D.
登録日2008-01-31
公開日2008-07-22
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the U2 snRNP protein Rds3p reveals a knotted zinc-finger motif.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1VJI
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Gene Product of At1g76680 from Arabidopsis thaliana
分子名称: 12-oxophytodienoate reductase (OPR1), FLAVIN MONONUCLEOTIDE
著者Wesenberg, G.E, Smith, D.W, Phillips Jr, G.N, Johnson, K.A, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
登録日2004-02-24
公開日2004-03-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献X-ray structure of Arabidopsis At1g77680, 12-oxophytodienoate reductase isoform 1.
Proteins, 61, 2005
2LD1
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Structures and chemical shift assignments for the ADD domain of the ATRX protein
分子名称: Transcriptional regulator ATRX, ZINC ION
著者Neuhaus, D, Yang, J.
登録日2011-05-13
公開日2011-06-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural consequences of disease-causing mutations in the ATRX-DNMT3-DNMT3L (ADD) domain of the chromatin-associated protein ATRX.
Proc.Natl.Acad.Sci.USA, 104, 2007
2LHR
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Solution structure of Staphylococcus aureus IsdH linker domain
分子名称: Iron-regulated surface determinant protein H
著者Spirig, T, Clubb, R.T, Malmirchegini, G.R, Robson, S.A.
登録日2011-08-12
公開日2012-11-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Staphylococcus aureus Uses a Novel Multidomain Receptor to Break Apart Human Hemoglobin and Steal Its Heme.
J.Biol.Chem., 288, 2013
1HVU
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HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE COMPLEXED WITH A 33-BASE NUCLEOTIDE RNA PSEUDOKNOT
分子名称: PROTEIN (HIV-1 REVERSE TRANSCRIPTASE), RNA (33 NUCLEOTIDE RNA PSEUDOKNOT)
著者Jaeger, J, Restle, T, Steitz, T.A.
登録日1998-06-30
公開日1999-01-13
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (4.75 Å)
主引用文献The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot inhibitor.
EMBO J., 17, 1998
2R14
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Structure of morphinone reductase in complex with tetrahydroNAD
分子名称: 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FLAVIN MONONUCLEOTIDE, Morphinone reductase
著者Costello, C.L, Scrutton, N.S, Leys, D.
登録日2007-08-22
公開日2008-07-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Mutagenesis of morphinone reductase induces multiple reactive configurations and identifies potential ambiguity in kinetic analysis of enzyme tunneling mechanisms.
J.Am.Chem.Soc., 129, 2007
2JYJ
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Re-refining the tetraloop-receptor RNA-RNA complex using NMR-derived restraints and Xplor-nih (2.18)
分子名称: RNA (43-MER)
著者Zuo, X, Wang, J, Foster, T.R, Schwieters, C.D, Tiede, D.M, Butcher, S.E, Wang, Y.
登録日2007-12-13
公開日2008-10-07
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献RNA helical packing in solution: NMR structure of a 30 kDa GAAA tetraloop-receptor complex.
J.Mol.Biol., 351, 2005
2BEH
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Crystal structure of antithrombin variant S137A/V317C/T401C with plasma latent antithrombin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, ...
著者Johnson, D.J, Luis, S.A, Huntington, J.A.
登録日2005-10-24
公開日2005-11-01
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of monomeric native antithrombin reveals a novel reactive center loop conformation.
J.Biol.Chem., 281, 2006
1JQS
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Fitting of L11 protein and elongation factor G (domain G' and V) in the cryo-em map of E. coli 70S ribosome bound with EF-G and GMPPCP, a nonhydrolysable GTP analog
分子名称: 50S Ribosomal protein L11, Elongation Factor G
著者Agrawal, R.K, Linde, J, Segupta, J, Nierhaus, K.H, Frank, J.
登録日2001-08-07
公開日2001-09-07
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (18 Å)
主引用文献Localization of L11 protein on the ribosome and elucidation of its involvement in EF-G-dependent translocation.
J.Mol.Biol., 311, 2001

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