8DHW
| Treponema lecithinolyticum beta-glucuronidase in complex with a UNC4917-glucuronide conjugate | 分子名称: | 4-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-2,7-bis(methylamino)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine, Glycosyl hydrolase family 2, TIM barrel domain protein, ... | 著者 | Lietzan, A.D, Redinbo, M.R. | 登録日 | 2022-06-28 | 公開日 | 2023-05-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Microbial beta-glucuronidases drive human periodontal disease etiology. Sci Adv, 9, 2023
|
|
8DHV
| |
8DHE
| |
7Y5C
| Cryo-EM structure of F-ATP synthase from Mycolicibacterium smegmatis (rotational state 2) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | 著者 | Saw, W.-G, Wong, C.F, Grueber, G. | 登録日 | 2022-06-16 | 公開日 | 2022-11-23 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors. Antimicrob.Agents Chemother., 66, 2022
|
|
7Y5A
| Cryo-EM structure of the Mycolicibacterium smegmatis F1-ATPase | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | 著者 | Wong, C.F, Saw, W.-G, Grueber, G. | 登録日 | 2022-06-16 | 公開日 | 2022-11-23 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors. Antimicrob.Agents Chemother., 66, 2022
|
|
7Y5B
| Cryo-EM structure of F-ATP synthase from Mycolicibacterium smegmatis (rotational state 1) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | 著者 | Saw, W.-G, Wong, C.F, Grueber, G. | 登録日 | 2022-06-16 | 公開日 | 2022-11-23 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors. Antimicrob.Agents Chemother., 66, 2022
|
|
7Y5D
| Cryo-EM structure of F-ATP synthase from Mycolicibacterium smegmatis (rotational state 3) (backbone) | 分子名称: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ... | 著者 | Saw, W.-G, Wong, C.F, Grueber, G. | 登録日 | 2022-06-16 | 公開日 | 2022-11-23 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (7.3 Å) | 主引用文献 | Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors. Antimicrob.Agents Chemother., 66, 2022
|
|
8DZK
| Dbr1 in complex with 5-mer cleavage product | 分子名称: | FE (II) ION, RNA (5'-R(P*(G46)P*UP*GP*UP*U)-3'), RNA lariat debranching enzyme, ... | 著者 | Clark, N.E, Taylor, A.B. | 登録日 | 2022-08-08 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of the RNA Lariat Debranching Enzyme Dbr1 with Hydrolyzed Phosphorothioate RNA Product. Biochemistry, 61, 2022
|
|
7YRY
| F1-ATPase of Acinetobacter baumannii | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | 著者 | Saw, W.-G, Grueber, G. | 登録日 | 2022-08-11 | 公開日 | 2023-06-21 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Atomic insights of an up and down conformation of the Acinetobacter baumannii F 1 -ATPase subunit epsilon and deciphering the residues critical for ATP hydrolysis inhibition and ATP synthesis. Faseb J., 37, 2023
|
|
8A8N
| |
4DK3
| Structure of Editosome protein | 分子名称: | RNA-editing complex protein MP81, single domain antibody VHH | 著者 | Park, Y.-J, Hol, W. | 登録日 | 2012-02-03 | 公開日 | 2012-07-04 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2. Nucleic Acids Res., 40, 2012
|
|
4DKA
| Structure of Editosome protein | 分子名称: | RNA-editing complex protein MP81, SODIUM ION, single domain antibody VHH | 著者 | Park, Y.-J, Hol, W. | 登録日 | 2012-02-03 | 公開日 | 2012-07-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2. Nucleic Acids Res., 40, 2012
|
|
6DXU
| |
6ED2
| Faecalibacterium prausnitzii beta-glucuronidase | 分子名称: | FORMIC ACID, GLYCEROL, Glycosyl hydrolase family 2, ... | 著者 | Pellock, S.J, Biernat, K.A, Redinbo, M.R. | 登録日 | 2018-08-08 | 公開日 | 2019-02-13 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases. Sci Rep, 9, 2019
|
|
6EC6
| |
1INH
| |
1ING
| |
6ED1
| Bacteroides dorei Beta-glucuronidase | 分子名称: | Glycosyl hydrolase family 2, sugar binding domain protein, SODIUM ION | 著者 | Biernat, K.A, Redinbo, M.R. | 登録日 | 2018-08-08 | 公開日 | 2019-02-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases. Sci Rep, 9, 2019
|
|
1IVB
| |
4ONA
| |
8GET
| R. hominis 2 beta-glucuronidase bound to norquetiapine-glucuronide | 分子名称: | 11-(4-beta-D-glucopyranuronosylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | 著者 | Simpson, J.B, Redinbo, M.R. | 登録日 | 2023-03-07 | 公開日 | 2024-03-20 | 最終更新日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Gut microbial beta-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics. Cell Host Microbe, 32, 2024
|
|
8HGX
| |
8GEO
| E. eligens beta-glucuronidase bound to 3-OH-desloratidine-glucuronide | 分子名称: | 8-chloro-11-(1-beta-D-glucopyranuronosylpiperidin-4-ylidene)-3-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, Beta-glucuronidase, GLYCEROL | 著者 | Simpson, J.B, Redinbo, M.R. | 登録日 | 2023-03-07 | 公開日 | 2024-03-20 | 最終更新日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Gut microbial beta-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics. Cell Host Microbe, 32, 2024
|
|
8GER
| E. eligens beta-glucuronidase bound to norquetiapine-glucuronide | 分子名称: | 11-(4-beta-D-glucopyranuronosylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine, Beta-glucuronidase | 著者 | Simpson, J.B, Lietzan, A.D, Redinbo, M.R. | 登録日 | 2023-03-07 | 公開日 | 2024-03-20 | 最終更新日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Gut microbial beta-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics. Cell Host Microbe, 32, 2024
|
|
3NYV
| |