1MU4
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6UC5
| Fab397 in complex with NPNA peptide | 分子名称: | Fab397 heavy chain, Fab397 light chain, NPNA peptide | 著者 | Pholcharee, T, Oyen, D, Wilson, I.A. | 登録日 | 2019-09-13 | 公開日 | 2020-01-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Diverse Antibody Responses to Conserved Structural Motifs in Plasmodium falciparum Circumsporozoite Protein. J.Mol.Biol., 432, 2020
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8QWT
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8QWX
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8QX0
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3L3O
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8OME
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8OMD
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8OMF
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8OMG
| Crystal structure of mKHK (apo) | 分子名称: | Ketohexokinase | 著者 | Ebenhoch, E, Pautsch, P. | 登録日 | 2023-03-31 | 公開日 | 2023-09-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Crystal structures of human and mouse ketohexokinase provide a structural basis for species- and isoform-selective inhibitor design. Acta Crystallogr D Struct Biol, 79, 2023
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8OMK
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3L5N
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6EM9
| S.aureus ClpC resting state, asymmetric map | 分子名称: | ATP-dependent Clp protease ATP-binding subunit ClpC | 著者 | Carroni, M, Mogk, A, Bukau, B, Franke, K. | 登録日 | 2017-10-01 | 公開日 | 2017-12-27 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (8.4 Å) | 主引用文献 | Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control. Elife, 6, 2017
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6EMW
| Structure of S.aureus ClpC in complex with MecA | 分子名称: | ATP-dependent Clp protease ATP-binding subunit, ATP-dependent Clp protease ATP-binding subunit ClpC, Adapter protein MecA, ... | 著者 | Carroni, M, Mogk, A, Bukau, B, Franke, K. | 登録日 | 2017-10-03 | 公開日 | 2017-12-27 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (11 Å) | 主引用文献 | Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control. Elife, 6, 2017
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6EM8
| S.aureus ClpC resting state, C2 symmetrised | 分子名称: | ATP-dependent Clp protease ATP-binding subunit ClpC | 著者 | Carroni, M, Mogk, A. | 登録日 | 2017-10-01 | 公開日 | 2017-12-27 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (8.4 Å) | 主引用文献 | Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control. Elife, 6, 2017
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6UUO
| Crystal structure of BRAF kinase domain bound to the PROTAC P4B | 分子名称: | N-(3-{5-[(1-acetylpiperidin-4-yl)(methyl)amino]-3-(pyrimidin-5-yl)-1H-pyrrolo[3,2-b]pyridin-1-yl}-2,4-difluorophenyl)propane-1-sulfonamide, Serine/threonine-protein kinase B-raf | 著者 | Maisonneuve, P, Posternak, G, Kurinov, I, Sicheri, F. | 登録日 | 2019-10-30 | 公開日 | 2020-06-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.288 Å) | 主引用文献 | Functional characterization of a PROTAC directed against BRAF mutant V600E. Nat.Chem.Biol., 16, 2020
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8PAQ
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3FW3
| Crystal Structure of soluble domain of CA4 in complex with Dorzolamide | 分子名称: | (4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE, Carbonic anhydrase 4, SULFATE ION, ... | 著者 | Greasley, S.E, Ferre, R.A.A, Paz, R, Wickersham, J. | 登録日 | 2009-01-16 | 公開日 | 2009-12-01 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Thioether benzenesulfonamide inhibitors of carbonic anhydrases II and IV: structure-based drug design, synthesis, and biological evaluation. Bioorg.Med.Chem., 18, 2010
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6B0E
| Crystal structure of Pfs25 in complex with the transmission blocking antibody 1260 | 分子名称: | 1260 antibody, heavy chain, light chain, ... | 著者 | Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P. | 登録日 | 2017-09-14 | 公開日 | 2017-11-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8, 2017
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6AZZ
| Crystal structure of Pfs25 in complex with the transmission blocking antibody 1190 | 分子名称: | 1190 antibody, heavy chain, light chain, ... | 著者 | Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P. | 登録日 | 2017-09-13 | 公開日 | 2017-11-08 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8, 2017
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6B0G
| Crystal structure of Pfs25 in complex with the transmission blocking antibody 1245 | 分子名称: | 1245 Antibody, Heavy Chain, Light Chain, ... | 著者 | McLeod, B, Scally, S.W, Bosch, A, King, C.R, Julien, J.P. | 登録日 | 2017-09-14 | 公開日 | 2017-11-08 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8, 2017
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3F7U
| Crystal Structure of soluble domain of CA4 in complex with small molecule. | 分子名称: | Carbonic anhydrase 4, N-(3-methoxypropyl)-2-(phenylsulfanyl)-5-sulfamoylpyridine-3-carboxamide, ZINC ION | 著者 | Pauly, T.A, Ferre, R.A.A, Greasley, S.E, Paz, R. | 登録日 | 2008-11-10 | 公開日 | 2009-09-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Thioether benzenesulfonamide inhibitors of carbonic anhydrases II and IV: structure-based drug design, synthesis, and biological evaluation. Bioorg.Med.Chem., 18, 2010
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6B0A
| Crystal structure of Pfs25 in complex with the transmission blocking antibody 1269 | 分子名称: | 1269 antibody, heavy chain, light chain, ... | 著者 | Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P. | 登録日 | 2017-09-14 | 公開日 | 2017-11-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8, 2017
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6B08
| Crystal structure of Pfs25 in complex with the transmission blocking antibody 1276 | 分子名称: | 1276 antibody, heavy chain, light chain, ... | 著者 | Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P. | 登録日 | 2017-09-14 | 公開日 | 2017-11-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8, 2017
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6B0H
| Crystal structure of Pfs25 in complex with the transmission blocking antibody 1262 | 分子名称: | 1,2-ETHANEDIOL, 1262 antibody, heavy chain, ... | 著者 | McLeod, B, Scally, S.W, Bosch, A, King, C.R, Julien, J.P. | 登録日 | 2017-09-14 | 公開日 | 2017-11-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8, 2017
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