9BA2

Crystal structure of the binary complex of DCAF1 and WDR5

Summary for 9BA2

• Entry DOI: 10.2210/pdb9ba2/pdb
• Descriptor: DDB1- and CUL4-associated factor 1, WD repeat-containing protein 5, IMIDAZOLE, ... (4 entities in total)
• Functional Keywords: e3 ligase, adaptor, protac, wdr, ternary complex, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 74801.11

Authors

Mabanglo, M.F.,Wilson, B.J.,Srivastava, S.,Al-awar, R.,Vedadi, M. (deposition date: 2024-04-03, release date: 2024-11-06)

• Primary citation: Mabanglo, M.F.,Vedadi, M.; Crystal structures of DCAF1-PROTAC-WDR5 complexes provide insight into DCAF1 substrate specificity; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.97 Å)