7W07
| Itaconate inducible LysR-Type Transcriptional regulator (ITCR) in complex with itaconate, Space group C121. | 分子名称: | 2-methylidenebutanedioic acid, SULFATE ION, Transcriptional regulator, ... | 著者 | Sun, P.K, Wang, B, Li, X.J. | 登録日 | 2021-11-17 | 公開日 | 2022-10-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | A genetically encoded fluorescent biosensor for detecting itaconate with subcellular resolution in living macrophages. Nat Commun, 13, 2022
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7W08
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7W06
| Itaconate inducible LysR-Type Transcriptional regulator (ITCR) in complex with itaconate (SeMet labeled), Space group C121. | 分子名称: | 2-methylidenebutanedioic acid, CHLORIDE ION, SULFATE ION, ... | 著者 | Sun, P.K, Wang, B, Wang, Z.X, Qi, S, Li, X.J. | 登録日 | 2021-11-17 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-16 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | A genetically encoded fluorescent biosensor for detecting itaconate with subcellular resolution in living macrophages. Nat Commun, 13, 2022
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3I81
| Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with BMS-754807 [1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-N-(6-fluoro-3-pyridinyl)-2-methyl-L-prolinamide] | 分子名称: | 1-{4-[(3-cyclopropyl-1H-pyrazol-5-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}-N-(6-fluoropyridin-3-yl)-2-methyl-L-proli namide, Insulin-like growth factor 1 receptor | 著者 | Sack, J.S. | 登録日 | 2009-07-09 | 公開日 | 2009-12-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Discovery of a 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitor (BMS-754807) of insulin-like growth factor receptor (IGF-1R) kinase in clinical development. J.Med.Chem., 52, 2009
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7X0L
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7X0H
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7X0P
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7X0G
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7X0K
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7X0O
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7X0Q
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7X0M
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7X0R
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7X0I
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7X0N
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7X0J
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7Y78
| Crystal structure of Cry78Aa | 分子名称: | 1,2-ETHANEDIOL, AMMONIUM ION, Toxin | 著者 | Cao, B.B, Nie, Y.F, Wang, N.C, Guan, Z.Y, Zhang, D.L, Zhang, J. | 登録日 | 2022-06-21 | 公開日 | 2022-08-31 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The crystal structure of Cry78Aa from Bacillus thuringiensis provides insights into its insecticidal activity. Commun Biol, 5, 2022
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7Y79
| Crystal structure of Cry78Aa | 分子名称: | Toxin | 著者 | Cao, B.B, Nie, Y.F, Wang, N.C, Guan, Z.Y, Zhang, D.L, Zhang, J. | 登録日 | 2022-06-21 | 公開日 | 2022-08-31 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | The crystal structure of Cry78Aa from Bacillus thuringiensis provides insights into its insecticidal activity. Commun Biol, 5, 2022
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7CCE
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7CKF
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7CG5
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7CG8
| Structure of the sensor domain (short construct) of the anti-sigma factor RsgI4 in Pseudobacteroides cellulosolvens | 分子名称: | 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, ACETATE ION, Anti-sigma factor RsgI, ... | 著者 | Dong, S, Feng, Y. | 登録日 | 2020-06-30 | 公開日 | 2021-06-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of the sensor domain of the anti-sigma factor RsgI4 in Pseudobacteroides cellulosolvens To Be Published
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7CG1
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7D5L
| Discovery of BMS-986144, a Third Generation, Pan Genotype NS3/4A Protease Inhibitor for the Treatment of Hepatitis C Virus Infection | 分子名称: | NS3/4A Protease, ZINC ION, [1,1,1-tris(fluoranyl)-2-methyl-propan-2-yl] ~{N}-[(1~{S},4~{R},6~{S},7~{Z},11~{R},13~{R},14~{S},18~{R})-13-ethyl-18-(7-fluoranyl-6-methoxy-isoquinolin-1-yl)oxy-11-methyl-4-[(1-methylcyclopropyl)sulfonylcarbamoyl]-2,15-bis(oxidanylidene)-3,16-diazatricyclo[14.3.0.0^{4,6}]nonadec-7-en-14-yl]carbamate | 著者 | Ghosh, K, Anumula, R, Kumar, A. | 登録日 | 2020-09-26 | 公開日 | 2020-12-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Discovery of BMS-986144, a Third-Generation, Pan-Genotype NS3/4A Protease Inhibitor for the Treatment of Hepatitis C Virus Infection. J.Med.Chem., 63, 2020
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7EJE
| human RAD51 post-synaptic complex | 分子名称: | DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA repair protein RAD51 homolog 1, ... | 著者 | Zhao, L.Y, Xu, J.F, Wang, H.W. | 登録日 | 2021-04-02 | 公開日 | 2022-03-16 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | 主引用文献 | Mechanisms of distinctive mismatch tolerance between Rad51 and Dmc1 in homologous recombination. Nucleic Acids Res., 49, 2021
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