4QUT
 
 | | Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) complexed with Histone H4-K(ac)12 | | 分子名称: | 1,2-ETHANEDIOL, ATPase family AAA domain-containing protein 2, Histone H4, ... | | 著者 | Chaikuad, A, Felletar, I, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2014-07-12 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells.
J Mol Cell Biol, 8, 2016
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6OAI
 | | Crystal structure of P[6] rotavirus vp8* complexed with LNFPI | | 分子名称: | Protease-sensitive outer capsid protein, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Xu, S, Liu, Y, Jiang, X, Kennedy, M.A. | | 登録日 | 2019-03-16 | | 公開日 | 2020-03-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Molecular basis of P[II] major human rotavirus VP8* domain recognition of histo-blood group antigens.
Plos Pathog., 16, 2020
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7KI5
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5D6C
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5ZUS
 | | P domain of GII.17-2014/15 | | 分子名称: | VP1 | | 著者 | Chen, Y, Li, X. | | 登録日 | 2018-05-08 | | 公開日 | 2018-10-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths.
J. Virol., 93, 2019
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5ZV5
 | | P domain of GII.17-2014/15 complexed with A-trisaccharide | | 分子名称: | VP1, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]alpha-D-galactopyranose | | 著者 | Chen, Y, Li, X. | | 登録日 | 2018-05-09 | | 公開日 | 2018-10-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths.
J. Virol., 93, 2019
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6ITJ
 | | Crystal structure of FGFR1 kinase domain in complex with compound 3 | | 分子名称: | 4-azanyl-3-(3,5-dimethyl-1-benzofuran-2-yl)-2-phenyl-6~{H}-pyrazolo[3,4-d]pyridazin-7-one, Fibroblast growth factor receptor 1 | | 著者 | Xu, Y, Liu, Q. | | 登録日 | 2018-11-23 | | 公開日 | 2019-10-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.994 Å) | | 主引用文献 | Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design.
J.Med.Chem., 62, 2019
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6IUO
 | | Crystal structure of FGFR4 kinase domain in complex with a covalent inhibitor | | 分子名称: | Fibroblast growth factor receptor 4, N-({4-[4-amino-3-(3,5-dimethyl-1-benzofuran-2-yl)-7-oxo-6,7-dihydro-2H-pyrazolo[3,4-d]pyridazin-2-yl]phenyl}methyl)prop-2-enamide | | 著者 | Xu, Y, Liu, Q. | | 登録日 | 2018-11-29 | | 公開日 | 2019-10-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design.
J.Med.Chem., 62, 2019
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6IUP
 | | Crystal structure of FGFR4 kinase domain in complex with compound 5 | | 分子名称: | DIMETHYL SULFOXIDE, Fibroblast growth factor receptor 4, N-{4-[4-amino-3-(3,5-dimethyl-1-benzofuran-2-yl)-7-oxo-6,7-dihydro-2H-pyrazolo[3,4-d]pyridazin-2-yl]phenyl}prop-2-enamide | | 著者 | Xu, Y, Liu, Q. | | 登録日 | 2018-11-29 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design.
J.Med.Chem., 62, 2019
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5A76
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3BY2
 | | Norwalk P polypeptide (228-523) | | 分子名称: | 58 kd capsid protein | | 著者 | Hegde, R, Bu, W. | | 登録日 | 2008-01-15 | | 公開日 | 2008-04-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for the receptor binding specificity of Norwalk virus.
J.Virol., 82, 2008
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3BY1
 | | Unliganded Norvalk Virus P domain | | 分子名称: | 58 kd capsid protein | | 著者 | Hegde, R, Bu, W. | | 登録日 | 2008-01-15 | | 公開日 | 2008-04-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Structural basis for the receptor binding specificity of Norwalk virus.
J.Virol., 82, 2008
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7ELG
 | | LC3B modificated with a covalent probe | | 分子名称: | 2-methylidene-5-thiophen-2-yl-cyclohexane-1,3-dione, Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | | 著者 | Fan, S, Wan, W. | | 登録日 | 2021-04-10 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | | 主引用文献 | Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein.
Angew.Chem.Int.Ed.Engl., 60, 2021
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3PZ6
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2OBS
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3PZ5
 | | The crystal structure of AaLeuRS-CP1-D20 | | 分子名称: | Leucyl-tRNA synthetase subunit alpha | | 著者 | Liu, R.J, Wang, E.D. | | 登録日 | 2010-12-14 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Peripheral insertion modulates the editing activity of the isolated CP1 domain of leucyl-tRNA synthetase
Biochem.J., 440, 2011
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2OBT
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6K0B
 | | cryo-EM structure of archaeal Ribonuclease P with mature tRNA | | 分子名称: | 50S ribosomal protein L7Ae, RPR, Ribonuclease P protein component 1, ... | | 著者 | Wan, F, Lan, P, Wu, J, Lei, M. | | 登録日 | 2019-05-05 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Cryo-electron microscopy structure of an archaeal ribonuclease P holoenzyme.
Nat Commun, 10, 2019
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6K0A
 | | cryo-EM structure of an archaeal Ribonuclease P | | 分子名称: | 50S ribosomal protein L7Ae, RPR, Ribonuclease P protein component 1, ... | | 著者 | Wan, F, Lan, P, Wu, J, Lei, M. | | 登録日 | 2019-05-05 | | 公開日 | 2019-06-19 | | 最終更新日 | 2022-12-21 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Cryo-electron microscopy structure of an archaeal ribonuclease P holoenzyme.
Nat Commun, 10, 2019
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3PZ0
 | | The crystal structure of AaLeuRS-CP1 | | 分子名称: | CALCIUM ION, Leucyl-tRNA synthetase subunit alpha | | 著者 | Liu, R.J, Wang, E.D. | | 登録日 | 2010-12-13 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Peripheral insertion modulates the editing activity of the isolated CP1 domain of leucyl-tRNA synthetase
Biochem.J., 440, 2011
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2OBR
 | | Crystal Structures of P Domain of Norovirus VA387 | | 分子名称: | Capsid protein | | 著者 | Cao, S, Lou, Z, Jiang, X, Zhang, X.C, Li, X, Rao, Z. | | 登録日 | 2006-12-20 | | 公開日 | 2007-04-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for the recognition of blood group trisaccharides by norovirus.
J.Virol., 81, 2007
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4LO9
 | | Human p53 Core Domain Mutant N235K | | 分子名称: | Cellular tumor antigen p53, ZINC ION | | 著者 | Wallentine, B.D, Wang, Y, Luecke, H. | | 登録日 | 2013-07-12 | | 公開日 | 2013-07-31 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures of oncogenic, suppressor and rescued p53 core-domain variants: mechanisms of mutant p53 rescue.
Acta Crystallogr.,Sect.D, 69, 2013
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4KVP
 | | Human p53 Core Domain Mutant V157F | | 分子名称: | Cellular tumor antigen p53, ZINC ION | | 著者 | Wallentine, B.D, Wang, Y, Luecke, H. | | 登録日 | 2013-05-22 | | 公開日 | 2013-07-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structures of oncogenic, suppressor and rescued p53 core-domain variants: mechanisms of mutant p53 rescue.
Acta Crystallogr.,Sect.D, 69, 2013
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4LOF
 | | Human p53 Core Domain Mutant V157F/N235K/N239Y | | 分子名称: | Cellular tumor antigen p53, ZINC ION | | 著者 | Wallentine, B.D, Wang, Y, Luecke, H. | | 登録日 | 2013-07-12 | | 公開日 | 2013-07-31 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of oncogenic, suppressor and rescued p53 core-domain variants: mechanisms of mutant p53 rescue.
Acta Crystallogr.,Sect.D, 69, 2013
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4LOE
 | | Human p53 Core Domain Mutant N239Y | | 分子名称: | Cellular tumor antigen p53, ZINC ION | | 著者 | Wallentine, B.D, Wang, Y, Luecke, H. | | 登録日 | 2013-07-12 | | 公開日 | 2013-07-31 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structures of oncogenic, suppressor and rescued p53 core-domain variants: mechanisms of mutant p53 rescue.
Acta Crystallogr.,Sect.D, 69, 2013
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