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3NS9
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BU of 3ns9 by Molmil
Crystal structure of CDK2 in complex with inhibitor BS-194
分子名称: (2S,3S)-3-{[7-(benzylamino)-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-5-yl]amino}butane-1,2,4-triol, Cell division protein kinase 2
著者Hazel, P, Freemont, P.S.
登録日2010-07-01
公開日2010-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献A Novel Pyrazolo[1,5-a]pyrimidine Is a Potent Inhibitor of Cyclin-Dependent Protein Kinases 1, 2, and 9, Which Demonstrates Antitumor Effects in Human Tumor Xenografts Following Oral Administration.
J.Med.Chem., 53, 2010
3II3
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BU of 3ii3 by Molmil
Structure of ORF157 from Acidianus filamentous Virus 1
分子名称: GLYCEROL, NICKEL (II) ION, Putative uncharacterized protein
著者Goulet, A, Redder, P, Pina, M, Prangishvili, D, van Tilbeurgh, H, Cambillau, C, Campanacci, V.
登録日2009-07-31
公開日2010-03-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献ORF157 from the archaeal virus Acidianus filamentous virus 1 defines a new class of nuclease
J.Virol., 84, 2010
5MYP
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BU of 5myp by Molmil
Structure of apo-TbALDH3
分子名称: Aldehyde dehydrogenase, GLYCEROL
著者Zoltner, M, Zhang, N, Horn, D, Field, M.C.
登録日2017-01-27
公開日2017-04-19
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Activation of an anti-trypanosomal benzoxaborole requires both host and parasite factors
To Be Published
1GBQ
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BU of 1gbq by Molmil
SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE
分子名称: GRB2, SOS-1
著者Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L.
登録日1996-12-23
公開日1997-09-04
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
J.Mol.Biol., 267, 1997
8OJT
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BU of 8ojt by Molmil
Crystal structure of the human IgD Fab - structure Fab2
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AZIDE ION, ...
著者Davies, A.M, Beavil, R.L, McDonnell, J.M.
登録日2023-03-24
公開日2023-06-14
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structures of the human IgD Fab reveal insights into C H 1 domain diversity.
Mol.Immunol., 159, 2023
5M35
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BU of 5m35 by Molmil
The molecular tweezer CLR01 stabilizes a disordered protein-protein interface
分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, GLYCEROL, ...
著者Bier, D, Ottmann, C.
登録日2016-10-14
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献The Molecular Tweezer CLR01 Stabilizes a Disordered Protein-Protein Interface.
J. Am. Chem. Soc., 139, 2017
7MCA
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BU of 7mca by Molmil
Structure of the S. cerevisiae origin recognition complex bound to the replication initiator Cdc6 and the ARS1 origin DNA.
分子名称: Cell division control protein 6, DNA (85-MER), MAGNESIUM ION, ...
著者Feng, X, Li, H.
登録日2021-04-01
公開日2021-06-02
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The structure of ORC-Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6.
Nat Commun, 12, 2021
8EU8
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BU of 8eu8 by Molmil
Cryo-EM structure of CH848 10.17DT DS-SOSIP-2P Env
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848 10.17DT SOSIP Envelope glycoprotein gp160
著者Wrapp, D, Acharya, P, Haynes, B.F.
登録日2022-10-18
公開日2023-01-04
最終更新日2023-02-08
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Structure-Based Stabilization of SOSIP Env Enhances Recombinant Ectodomain Durability and Yield.
J.Virol., 97, 2023
8OJS
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BU of 8ojs by Molmil
Crystal structure of the human IgD Fab - structure Fab1
分子名称: 1,2-ETHANEDIOL, Human IgD Fab heavy chain, Human IgD Fab light chain, ...
著者Davies, A.M, Beavil, R.L, McDonnell, J.M.
登録日2023-03-24
公開日2023-06-14
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal structures of the human IgD Fab reveal insights into C H 1 domain diversity.
Mol.Immunol., 159, 2023
8OJU
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BU of 8oju by Molmil
Crystal structure of the human IgD Fab - structure Fab3
分子名称: 1,2-ETHANEDIOL, Human IgD Fab heavy chain, Human IgD Fab light chain, ...
著者Davies, A.M, Beavil, R.L, McDonnell, J.M.
登録日2023-03-24
公開日2023-06-14
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structures of the human IgD Fab reveal insights into C H 1 domain diversity.
Mol.Immunol., 159, 2023
8OJV
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BU of 8ojv by Molmil
Crystal structure of the human IgD Fab - structure Fab4
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Davies, A.M, Beavil, R.L, McDonnell, J.M.
登録日2023-03-24
公開日2023-06-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of the human IgD Fab reveal insights into C H 1 domain diversity.
Mol.Immunol., 159, 2023
8OWI
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BU of 8owi by Molmil
Crystal structure of the corona-targeting domain of CENP-E
分子名称: Centromere-associated protein E
著者Legal, T, Davies, O.R, Welburn, J.P.I.
登録日2023-04-28
公開日2023-06-21
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献A conserved CENP-E region mediates BubR1-independent recruitment to the outer corona at mitotic onset.
Curr.Biol., 34, 2024
5M36
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BU of 5m36 by Molmil
The molecular tweezer CLR01 stabilizes a disordered protein-protein interface
分子名称: (1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene, 14-3-3 protein zeta/delta, BENZOIC ACID, ...
著者Bier, D, Ottmann, C.
登録日2016-10-14
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The Molecular Tweezer CLR01 Stabilizes a Disordered Protein-Protein Interface.
J. Am. Chem. Soc., 139, 2017
5M37
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BU of 5m37 by Molmil
The molecular tweezer CLR01 stabilizes a disordered protein-protein interface
分子名称: (1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene, 14-3-3 protein zeta/delta, BENZOIC ACID, ...
著者Bier, D, Ottmann, C.
登録日2016-10-14
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The Molecular Tweezer CLR01 Stabilizes a Disordered Protein-Protein Interface.
J. Am. Chem. Soc., 139, 2017
5O7M
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BU of 5o7m by Molmil
Single-shot pink beam serial crystallography: Phycocyanin (One chip, chip_1)
分子名称: C-phycocyanin alpha chain, C-phycocyanin beta chain, PHYCOCYANOBILIN
著者Meents, A, Oberthuer, D, Lieske, J, Srajer, V, Sarrou, I.
登録日2017-06-09
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Pink-beam serial crystallography.
Nat Commun, 8, 2017
3II2
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BU of 3ii2 by Molmil
Structure of ORF157 from Acidianus Filamentous Virus 1
分子名称: CHLORIDE ION, GLYCEROL, MERCURY (II) ION, ...
著者Goulet, A, Porciero, S, Prangishvili, D, van Tilbeurgh, H, Cambillau, C, Campanacci, V.
登録日2009-07-31
公開日2010-03-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献ORF157 from the archaeal virus Acidianus filamentous virus 1 defines a new class of nuclease
J.Virol., 84, 2010
2GD7
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BU of 2gd7 by Molmil
The Structure of the Cyclin T-binding domain of Hexim1 reveals the molecular basis for regulation of transcription elongation
分子名称: HEXIM1 protein
著者Dames, S.A.
登録日2006-03-15
公開日2007-06-12
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb.
Proc.Natl.Acad.Sci.Usa, 104, 2007
5NXY
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BU of 5nxy by Molmil
Crystal structure of OpuAC from B. subtilis in complex with Arsenobetaine
分子名称: 1,2-ETHANEDIOL, 2-(trimethyl-lambda~5~-arsanyl)ethanol, Osmotically activated L-carnitine/choline ABC transporter substrate-binding protein OpuCC
著者Hofmann, T, Bremer, E, Schmitt, L, Smits, S.
登録日2017-05-11
公開日2018-03-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Arsenobetaine: an ecophysiologically important organoarsenical confers cytoprotection against osmotic stress and growth temperature extremes.
Environ. Microbiol., 20, 2018
5NXX
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BU of 5nxx by Molmil
Crystal structure of OpuAC from B. subtilis in complex with Arsenobetaine
分子名称: (trimethylarsonio)acetate, Glycine betaine ABC transport system glycine betaine-binding protein OpuAC
著者Hofmann, T, Bremer, E, Schmitt, L, Smits, S.
登録日2017-05-11
公開日2018-03-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Arsenobetaine: an ecophysiologically important organoarsenical confers cytoprotection against osmotic stress and growth temperature extremes.
Environ. Microbiol., 20, 2018
3ILD
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BU of 3ild by Molmil
Structure of ORF157-K57A from Acidianus filamentous virus 1
分子名称: MAGNESIUM ION, Putative uncharacterized protein
著者Goulet, A, Lichiere, J, Prangishvili, D, van Tilbeurgh, H, Cambillau, C, Campanacci, V.
登録日2009-08-07
公開日2010-03-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献ORF157 from the archaeal virus Acidianus filamentous virus 1 defines a new class of nuclease
J.Virol., 84, 2010
3ILE
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BU of 3ile by Molmil
Crystal structure of ORF157-E86A of Acidianus filamentous virus 1
分子名称: NICKEL (II) ION, Putative uncharacterized protein
著者Goulet, A, Lichiere, J, Prangishvili, D, van Tilbeurgh, H, Cambillau, C, Campanacci, V.
登録日2009-08-07
公開日2010-03-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献ORF157 from the archaeal virus Acidianus filamentous virus 1 defines a new class of nuclease
J.Virol., 84, 2010
2C8T
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BU of 2c8t by Molmil
The 3.0 A Resolution Structure of Caseinolytic Clp Protease 1 from Mycobacterium tuberculosis
分子名称: ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1
著者Ingvarsson, H, Hogbom, M, Jones, T.A, Unge, T.
登録日2005-12-07
公開日2007-02-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Insights Into the Inter-Ring Plasticity of Caseinolytic Proteases from the X-Ray Structure of Mycobacterium Tuberculosis Clpp1.
Acta Crystallogr.,Sect.D, 63, 2007
8RON
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BU of 8ron by Molmil
Crystal structure of human FAD synthase, isoform 2
分子名称: Isoform 2 of FAD synthase
著者Leo, G, Capaldi, S.
登録日2024-01-11
公開日2024-04-10
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insights into the bifunctional enzyme human FAD synthase.
Structure, 32, 2024
8ROM
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BU of 8rom by Molmil
Crystal structure of human FAD synthase PAPS domain in complex with FAD
分子名称: FAD synthase, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION
著者Leo, G, Capaldi, S.
登録日2024-01-11
公開日2024-04-10
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structural insights into the bifunctional enzyme human FAD synthase.
Structure, 32, 2024
2GBQ
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BU of 2gbq by Molmil
SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, 15 STRUCTURES
分子名称: GRB2, SOS-1
著者Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L.
登録日1996-12-23
公開日1997-09-04
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
J.Mol.Biol., 267, 1997

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