5NXY

Crystal structure of OpuAC from B. subtilis in complex with Arsenobetaine

Summary for 5NXY

Entry DOI	10.2210/pdb5nxy/pdb
Related	3R6U
Descriptor	Osmotically activated L-carnitine/choline ABC transporter substrate-binding protein OpuCC, 2-(trimethyl-lambda~5~-arsanyl)ethanol, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	substrate binding protein arseen, b. subtilis, choline-binding protein
Biological source	Bacillus subtilis
Total number of polymer chains	2
Total formula weight	64553.22
Authors	Hofmann, T.,Bremer, E.,Schmitt, L.,Smits, S. (deposition date: 2017-05-11, release date: 2018-03-14, Last modification date: 2024-01-17)
Primary citation	Hoffmann, T.,Warmbold, B.,Smits, S.H.J.,Tschapek, B.,Ronzheimer, S.,Bashir, A.,Chen, C.,Rolbetzki, A.,Pittelkow, M.,Jebbar, M.,Seubert, A.,Schmitt, L.,Bremer, E. Arsenobetaine: an ecophysiologically important organoarsenical confers cytoprotection against osmotic stress and growth temperature extremes. Environ. Microbiol., 20:305-323, 2018 Cited by PubMed: 29159878 DOI: 10.1111/1462-2920.13999 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation