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2E63
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BU of 2e63 by Molmil
Solution structure of the NEUZ domain in KIAA1787 protein
分子名称: KIAA1787 protein
著者He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-12-25
公開日2007-06-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural and functional characterization of the NHR1 domain of the Drosophila neuralized E3 ligase in the notch signaling pathway.
J.Mol.Biol., 393, 2009
2D8B
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BU of 2d8b by Molmil
Solution structure of the second tandem cofilin-domain of mouse twinfilin
分子名称: Twinfilin-1
著者Goroncy, A.K, Kigawa, T, Koshiba, S, Sato, M, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-02
公開日2006-06-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献NMR solution structures of actin depolymerizing factor homology domains
Protein Sci., 18, 2009
2DWG
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BU of 2dwg by Molmil
RUN domain of Rap2 interacting protein x, crystallized in P2(1)2(1)2(1) space group
分子名称: Protein RUFY3
著者Kukimoto-Niino, M, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-08-11
公開日2006-10-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Crystal Structure of the RUN Domain of the RAP2-interacting Protein x
J.Biol.Chem., 281, 2006
2DWK
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Crystal structure of the RUN domain of mouse Rap2 interacting protein x
分子名称: Protein RUFY3
著者Kukimoto-Niino, M, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-08-15
公開日2006-08-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the RUN Domain of the RAP2-interacting Protein x
J.Biol.Chem., 281, 2006
2DXS
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BU of 2dxs by Molmil
Crystal structure of HCV NS5B RNA polymerase complexed with a tetracyclic inhibitor
分子名称: Genome polyprotein, N-[(13-CYCLOHEXYL-6,7-DIHYDROINDOLO[1,2-D][1,4]BENZOXAZEPIN-10-YL)CARBONYL]-2-METHYL-L-ALANINE
著者Adachi, T, Tsuruha, J, Doi, S, Murase, K, Ikegashira, K, Watanabe, S, Uehara, K, Orita, T, Nomura, A, Kamada, M.
登録日2006-08-30
公開日2006-12-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of Conformationally Constrained Tetracyclic Compounds as Potent Hepatitis C Virus NS5B RNA Polymerase Inhibitors
J.Med.Chem., 49, 2006
2E61
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Solution structure of the zf-CW domain in zinc finger CW-type PWWP domain protein 1
分子名称: ZINC ION, Zinc finger CW-type PWWP domain protein 1
著者He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-12-25
公開日2007-06-26
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural insight into the zinc finger CW domain as a histone modification reader
Structure, 18, 2010
2ELL
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BU of 2ell by Molmil
Solution structure of the Leucine Rich Repeat of human Acidic leucine-rich nuclear phosphoprotein 32 family member B
分子名称: Acidic leucine-rich nuclear phosphoprotein 32 family member B
著者Tochio, N, Koshiba, S, Watanabe, S, Harada, T, Umehara, T, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-27
公開日2008-04-01
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of histone chaperone ANP32B: interaction with core histones H3-H4 through its acidic concave domain.
J.Mol.Biol., 401, 2010
2ZIS
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BU of 2zis by Molmil
Crystal Structure of rat protein farnesyltransferase complexed with a bezoruran inhibitor and FPP
分子名称: 3-{2-[(S)-(4-cyanophenyl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl]-5-nitro-1-benzofuran-7-yl}benzonitrile, ACETIC ACID, FARNESYL DIPHOSPHATE, ...
著者Fukami, T.A, Sogabe, S, Nagata, Y, Kondoh, O, Ishii, N.
登録日2008-02-22
公開日2009-02-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Synthesis and structure-activity relationships of novel benzofuran farnesyltransferase inhibitors
Bioorg.Med.Chem.Lett., 19, 2009
2ZIR
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Crystal Structure of rat protein farnesyltransferase complexed with a benzofuran inhibitor and FPP
分子名称: 2-[(S)-(4-chlorophenyl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl]-N-morpholin-4-yl-7-phenyl-1-benzofuran-5-carboxamide, FARNESYL DIPHOSPHATE, GLYCEROL, ...
著者Fukami, T.A, Sogabe, S, Nagata, Y, Kondoh, O, Ishii, N.
登録日2008-02-22
公開日2009-02-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Synthesis and structure-activity relationships of novel benzofuran farnesyltransferase inhibitors
Bioorg.Med.Chem.Lett., 19, 2009
2HWA
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BU of 2hwa by Molmil
Crystal structure of Lys12Thr/Cys117Val mutant of human acidic fibroblast growth factor at 1.65 angstrom resolution.
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
登録日2006-08-01
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
2HW9
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Crystal structure of Lys12Cys/Cys117Val mutant of human acidic fibroblast Growth factor at 1.60 angstrom resolution.
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
登録日2006-08-01
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
2HWM
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BU of 2hwm by Molmil
Crystal structure of Lys12Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.60 angstrom resolution
分子名称: FORMIC ACID, Heparin-binding growth factor 1
著者Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
登録日2006-08-01
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
2HZ9
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BU of 2hz9 by Molmil
Crystal structure of Lys12Val/Asn95Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.70 angstrom resolution.
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
登録日2006-08-08
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Spackling the Crack: Stabilizing Human Fibroblast Growth Factor-1 by Targeting the N and C terminus beta-Strand Interactions
J.Mol.Biol., 371, 2007
2GFS
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P38 Kinase Crystal Structure in complex with RO3201195
分子名称: Mitogen-Activated Protein Kinase 14, [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONE
著者Harris, S.F, Bertrand, J, Villasenor, A.
登録日2006-03-23
公開日2006-04-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.752 Å)
主引用文献Discovery of S-[5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(2,3-dihydroxypropoxy)phenyl]-methanone (RO3201195), and Orally Bioavailable and Highly Selective Inhibitor of p38 Map Kinase
J.Med.Chem., 49, 2006

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