6MDU
 
 | | Crystal structure of NDM-1 with compound 7 | | 分子名称: | 1,5-diphenyl-N-(1H-tetrazol-5-yl)-1H-pyrazole-3-carboxamide, GLYCEROL, Metallo-beta-lactamase type 2, ... | | 著者 | Akhtar, A, Chen, Y. | | 登録日 | 2018-09-05 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Active-Site Druggability of Carbapenemases and Broad-Spectrum Inhibitor Discovery.
Acs Infect Dis., 5, 2019
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8E2B
 | | N-terminal domain of S. aureus GpsB | | 分子名称: | Cell cycle protein GpsB, GLYCEROL | | 著者 | Sacco, M, Chen, Y. | | 登録日 | 2022-08-14 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Staphylococcus aureus FtsZ and PBP4 bind to the conformationally dynamic N-terminal domain of GpsB.
Elife, 13, 2024
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8E2C
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2JWS
 | | Solution NMR structures of two designed proteins with 88% sequence identity but different fold and function | | 分子名称: | Ga88 | | 著者 | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | | 登録日 | 2007-10-24 | | 公開日 | 2008-09-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structures of two designed proteins with high sequence identity but different fold and function
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2MH8
 | | GA-79-MBP cs-rosetta structures | | 分子名称: | GA-79-MBP, maltose binding protein | | 著者 | He, Y, Chen, Y, Porter, L, Bryan, P, Orban, J. | | 登録日 | 2013-11-19 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Subdomain interactions foster the design of two protein pairs with 80% sequence identity but different folds.
Biophys.J., 108, 2015
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3C5W
 | | Complex between PP2A-specific methylesterase PME-1 and PP2A core enzyme | | 分子名称: | PP2A A subunit, PP2A C subunit, PP2A-specific methylesterase PME-1 | | 著者 | Xing, Y, Li, Z, Chen, Y, Stock, J, Jeffrey, P.D, Shi, Y. | | 登録日 | 2008-02-01 | | 公開日 | 2008-04-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural mechanism of demethylation and inactivation of protein phosphatase 2A.
Cell(Cambridge,Mass.), 133, 2008
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2LHG
 | | GB98-T25I solution structure | | 分子名称: | GB98 | | 著者 | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | | 登録日 | 2011-08-08 | | 公開日 | 2012-02-29 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mutational tipping points for switching protein folds and functions.
Structure, 20, 2012
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2JWU
 | | Solution NMR structures of two designed proteins with 88% sequence identity but different fold and function | | 分子名称: | Gb88 | | 著者 | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | | 登録日 | 2007-10-25 | | 公開日 | 2008-09-09 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structures of two designed proteins with high sequence identity but different fold and function
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2KDL
 | | NMR structures of GA95 and GB95, two designed proteins with 95% sequence identity but different folds and functions | | 分子名称: | designed protein | | 著者 | He, Y, Alexander, P, Chen, Y, Bryan, P, Orban, J. | | 登録日 | 2009-01-12 | | 公開日 | 2009-12-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A minimal sequence code for switching protein structure and function.
Proc.Natl.Acad.Sci.USA, 106, 2009
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3C96
 | | Crystal structure of the flavin-containing monooxygenase phzS from Pseudomonas aeruginosa. Northeast Structural Genomics Consortium target PaR240 | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Flavin-containing monooxygenase | | 著者 | Vorobiev, S.M, Chen, Y, Seetharaman, J, Wang, D, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2008-02-15 | | 公開日 | 2008-02-26 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the flavin-containing monooxygenase phzS from Pseudomonas aeruginosa.
To be Published
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3C5V
 | | PP2A-specific methylesterase apo form (PME) | | 分子名称: | Protein phosphatase methylesterase 1 | | 著者 | Xing, Y, Li, Z, Chen, Y, Stock, J, Jeffrey, P.D, Shi, Y. | | 登録日 | 2008-02-01 | | 公開日 | 2008-04-15 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural mechanism of demethylation and inactivation of protein phosphatase 2A.
Cell(Cambridge,Mass.), 133, 2008
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2LHE
 | | Gb98-T25I,L20A | | 分子名称: | Gb98 | | 著者 | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | | 登録日 | 2011-08-08 | | 公開日 | 2012-02-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mutational tipping points for switching protein folds and functions.
Structure, 20, 2012
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2LHD
 | | GB98 solution structure | | 分子名称: | GB98 | | 著者 | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | | 登録日 | 2011-08-08 | | 公開日 | 2012-02-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mutational tipping points for switching protein folds and functions.
Structure, 20, 2012
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2LU1
 | | pfsub2 solution NMR structure | | 分子名称: | Subtilase | | 著者 | He, Y, Chen, Y, Ruan, B, O'Brochta, D, Bryan, P, Orban, J. | | 登録日 | 2012-06-06 | | 公開日 | 2012-10-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of a sheddase inhibitor prodomain from the malarial parasite Plasmodium falciparum.
Proteins, 80, 2012
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4ZOU
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5A9Y
 | | Structure of ppGpp BipA | | 分子名称: | GTP-BINDING PROTEIN, GUANOSINE-5',3'-TETRAPHOSPHATE | | 著者 | Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y.-G. | | 登録日 | 2015-07-23 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5A9X
 | | Structure of GDP bound BipA | | 分子名称: | GTP-BINDING PROTEIN, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y.-G. | | 登録日 | 2015-07-23 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4N4Y
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5AA0
 | | Complex of Thermous thermophilus ribosome (A-and P-site tRNA) bound to BipA-GDPCP | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... | | 著者 | Kumar, V, Chen, Y, Ahmed, T, Tan, J, Ero, R, Bhushan, S, Gao, Y.-G. | | 登録日 | 2015-07-23 | | 公開日 | 2015-10-14 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (5 Å) | | 主引用文献 | Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5A9W
 | | Structure of GDPCP BipA | | 分子名称: | GTP-BINDING PROTEIN, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | | 著者 | Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y. | | 登録日 | 2015-07-23 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
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1RYU
 | | Solution Structure of the SWI1 ARID | | 分子名称: | SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1 | | 著者 | Kim, S, Zhang, Z, Upchurch, S, Isern, N, Chen, Y. | | 登録日 | 2003-12-22 | | 公開日 | 2004-05-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and DNA-binding sites of the SWI1 AT-rich interaction domain (ARID) suggest determinants for sequence-specific DNA recognition.
J.Biol.Chem., 279, 2004
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1R78
 | | CDK2 complex with a 4-alkynyl oxindole inhibitor | | 分子名称: | 4-((3R,4S,5R)-4-AMINO-3,5-DIHYDROXY-HEX-1-YNYL)-5-FLUORO-3-[1-(3-METHOXY-1H-PYRROL-2-YL)-METH-(Z)-YLIDENE]-1,3-DIHYDRO-INDOL-2-ONE, Cell division protein kinase 2 | | 著者 | Luk, K.-C, Simcox, M.E, Schutt, A, Rowan, K, Thompson, T, Chen, Y, Kammlott, U, DePinto, W, Dunten, P, Dermatakis, A. | | 登録日 | 2003-10-20 | | 公開日 | 2004-01-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A new series of potent oxindole inhibitors of CDK2
Bioorg.Med.Chem.Lett., 14, 2004
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5A9Z
 | | Complex of Thermous thermophilus ribosome bound to BipA-GDPCP | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Kumar, V, Chen, Y, Ahmed, T, Tan, J, Ero, R, Bhushan, S, Gao, Y.-G. | | 登録日 | 2015-07-23 | | 公開日 | 2015-10-14 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5A9V
 | | Structure of apo BipA | | 分子名称: | GTP-BINDING PROTEIN | | 著者 | Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y. | | 登録日 | 2015-07-23 | | 公開日 | 2015-09-02 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | | 主引用文献 | Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
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1SQ4
 | | Crystal Structure of the Putative Glyoxylate Induced Protein from Pseudomonas aeruginosa, Northeast Structural Genomics Target PaR14 | | 分子名称: | Glyoxylate-induced Protein, THIOCYANATE ION | | 著者 | Forouhar, F, Chen, Y, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2004-03-17 | | 公開日 | 2004-04-06 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structure of the Putative Glyoxylate Induced Protein from Pseudomonas aeruginosa, Northeast Structural Genomics Target PaR14
To be Published
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