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6UUH
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BU of 6uuh by Molmil
Crystal structure of broad and potent HIV-1 neutralizing antibody 438-B11
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, B11 Fab Heavy Chain, B11 Fab Light Chain, ...
著者Kumar, S, Wilson, I.A.
登録日2019-10-30
公開日2020-09-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A V H 1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite.
Sci Adv, 6, 2020
6UYM
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BU of 6uym by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2mc3-v6 redesigned core from genotype 1a bound to broadly neutralizing antibody AR3C
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Tzarum, N, Wilson, I.A, Zhu, J.
登録日2019-11-13
公開日2020-04-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.848 Å)
主引用文献Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines.
Sci Adv, 6, 2020
6UYF
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BU of 6uyf by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2mc3-v1 redesigned core from genotype 6a bound to broadly neutralizing antibody AR3B
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Tzarum, N, Wilson, I.A, Zhu, J.
登録日2019-11-13
公開日2020-04-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines.
Sci Adv, 6, 2020
6UYG
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BU of 6uyg by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2c3 core from genotype 6a bound to broadly neutralizing antibody AR3A and non neutralizing antibody E1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Tzarum, N, Wilson, I.A, Zhu, J.
登録日2019-11-13
公開日2020-04-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.375 Å)
主引用文献Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines.
Sci Adv, 6, 2020
6V6W
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BU of 6v6w by Molmil
Crystal structure of antibody 438-B11 DSS mutant (Cys98A-100aA) in complex with an uncleaved prefusion optimized (UFO) soluble BG505 trimer and Fab 35O22
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab Heavy chain, ...
著者Kumar, S, Wilson, I.A.
登録日2019-12-06
公開日2020-09-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (6.5 Å)
主引用文献A VH1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite
Sci Adv, 6, 2020
6VOS
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BU of 6vos by Molmil
Crystal structure of macaque anti-HIV-1 antibody RM20J
分子名称: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, HEXAETHYLENE GLYCOL, NONAETHYLENE GLYCOL, ...
著者Yuan, M, Wilson, I.A.
登録日2020-01-31
公開日2020-09-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.299 Å)
主引用文献Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
Plos Pathog., 16, 2020
6VSR
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BU of 6vsr by Molmil
Crystal structure of macaque anti-HIV-1 antibody RM20F
分子名称: RM20F Fab Heavy Chain, RM20F Fab Light Chain, SULFATE ION
著者Oyen, D, Yuan, M, Wilson, I.A.
登録日2020-02-11
公開日2020-09-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.176 Å)
主引用文献Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
Plos Pathog., 16, 2020
6VOR
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BU of 6vor by Molmil
Crystal structure of macaque anti-HIV-1 antibody RM20E1
分子名称: GLYCINE, RM20E1 Fab heavy chain, RM20E1 Fab light chain
著者Yuan, M, Wilson, I.A.
登録日2020-01-31
公開日2020-09-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
Plos Pathog., 16, 2020
6WJ0
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BU of 6wj0 by Molmil
Crystal structure of Fab 54-4H03
分子名称: Fab 54-4H03 heavy chain, Fab 54-4H03 light chain, GLYCEROL
著者Wu, N.C, Wilson, I.A.
登録日2020-04-11
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor.
Cell Host Microbe, 28, 2020
6WO3
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BU of 6wo3 by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody U1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Tzarum, N, Wilson, I.A, Law, M.
登録日2020-04-24
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.382 Å)
主引用文献An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
6WJ1
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BU of 6wj1 by Molmil
Crystal structure of Fab 54-4H03 bound to H1 influenza hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 54-4H03 heavy chain, ...
著者Wu, N.C, Wilson, I.A.
登録日2020-04-11
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.503 Å)
主引用文献Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor.
Cell Host Microbe, 28, 2020
6WO4
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BU of 6wo4 by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody HC11
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Tzarum, N, Wilson, I.A, Law, M.
登録日2020-04-24
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.349 Å)
主引用文献An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
6WCR
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BU of 6wcr by Molmil
Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule F0045(S)
分子名称: (2,4-dichlorophenyl)[(2S)-2-phenylmorpholin-4-yl]methanone, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者kadam, R.U, Wilson, I.A.
登録日2020-03-31
公開日2020-08-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen.
Proc.Natl.Acad.Sci.USA, 117, 2020
6X1V
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BU of 6x1v by Molmil
Structure of pHis Fab (SC44-8) in complex with pHis mimetic peptide
分子名称: 1,2-ETHANEDIOL, ACLYana-3-pTza peptide, SC44-8 Heavy chain, ...
著者Kalagiri, R, Stanfield, R, Wilson, I.A, Hunter, T.
登録日2020-05-19
公開日2021-02-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 118, 2021
6WIY
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BU of 6wiy by Molmil
Crystal structure of Fab 54-1G05
分子名称: Fab 54-1G05 heavy chain, Fab 54-1G05 light chain, GLYCEROL
著者Wu, N.C, Wilson, I.A.
登録日2020-04-11
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor.
Cell Host Microbe, 28, 2020
6WOS
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BU of 6wos by Molmil
Structure of broadly neutralizing antibody AR3B
分子名称: Fab AR3B heavy chain, Fab AR3B light chain
著者Tzarum, N, Wilson, I.A, Law, M.
登録日2020-04-25
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.645 Å)
主引用文献An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
6WOQ
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BU of 6woq by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 1a bound to neutralizing antibody HC1AM and non neutralizing antibody E1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Tzarum, N, Wilson, I.A, Law, M.
登録日2020-04-25
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.667 Å)
主引用文献An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
6WO5
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BU of 6wo5 by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 1a bound to neutralizing antibody 212.1.1 and non neutralizing antibody E1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Tzarum, N, Wilson, I.A, Law, M.
登録日2020-04-24
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.619 Å)
主引用文献An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
6W41
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BU of 6w41 by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with human antibody CR3022
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR3022 Fab heavy chain, CR3022 Fab light chain, ...
著者Yuan, M, Wu, N.C, Zhu, X.Y, Wilson, I.A.
登録日2020-03-09
公開日2020-03-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.084 Å)
主引用文献A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV.
Science, 368, 2020
6WIZ
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BU of 6wiz by Molmil
Crystal structure of Fab 54-1G05 bound to H1 influenza hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 54-1G05 heavy chain, Fab 54-1G05 light chain, ...
著者Wu, N.C, Wilson, I.A.
登録日2020-04-11
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor.
Cell Host Microbe, 28, 2020
6X1T
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BU of 6x1t by Molmil
Structure of pHis Fab (SC50-3) in complex with pHis mimetic peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kalagiri, R, Stanfield, R.L, Wilson, I.A, Hunter, T.
登録日2020-05-19
公開日2021-02-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 118, 2021
6X1W
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BU of 6x1w by Molmil
Structure of pHis Fab (SC56-2) in complex with pHis mimetic peptide
分子名称: ACLYana-3-pTza peptide, SC56-2 Heavy chain, SC56-2 Light chain
著者Kalagiri, R, Stanfield, R, Wilson, I.A, Hunter, T.
登録日2020-05-19
公開日2021-02-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 118, 2021
6WOR
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BU of 6wor by Molmil
Structure of the broadly neutralizing antibody HC1AM
分子名称: Fab HC1AM heavy chain, Fab HC1AM light chain
著者Tzarum, N, Wilson, I.A, Law, M.
登録日2020-04-25
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
6X1U
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BU of 6x1u by Molmil
Structure of pHis Fab (SC39-4) in complex with pHis mimetic peptide
分子名称: 1,2-ETHANEDIOL, ACETATE ION, ACLYana-3-pTza peptide, ...
著者Kalagiri, R, Stanfield, R, Wilson, I.A, Hunter, T.
登録日2020-05-19
公開日2021-02-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.641 Å)
主引用文献Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 118, 2021
4MZE
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BU of 4mze by Molmil
Crystal structure of hPIV3 hemagglutinin-neuraminidase, H552Q/Q559R mutant
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Xu, R, Wilson, I.A.
登録日2013-09-30
公開日2013-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Interaction between the hemagglutinin-neuraminidase and fusion glycoproteins of human parainfluenza virus type III regulates viral growth in vivo.
MBio, 4, 2013

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