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5V5B
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BU of 5v5b by Molmil
KVQIINKKLD, Structure of the amyloid spine from microtubule associated protein tau Repeat 2
分子名称: Microtubule-associated protein tau
著者Seidler, P.M, Sawaya, M.R, Rodriguez, J.A, Eisenberg, D.S, Cascio, D, Boyer, D.R.
登録日2017-03-13
公開日2018-02-07
最終更新日2024-03-13
実験手法ELECTRON CRYSTALLOGRAPHY (1.5 Å)
主引用文献Structure-based inhibitors of tau aggregation.
Nat Chem, 10, 2018
5V8C
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BU of 5v8c by Molmil
LytR-Csp2A-Psr enzyme from Actinomyces oris
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, COBALT (II) ION, PHOSPHATE ION, ...
著者Amer, B.R, Sawaya, M.R, Liauw, B, Fu, J.Y, Ton-That, H, Clubb, R.T.
登録日2017-03-21
公開日2018-04-11
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure and Mechanism of LcpA, a Phosphotransferase That Mediates Glycosylation of a Gram-Positive Bacterial Cell Wall-Anchored Protein.
MBio, 10, 2019
4RKP
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BU of 4rkp by Molmil
Crystal Structure of Mevalonate-3-Kinase from Thermoplasma acidophilum (apo form)
分子名称: ACETATE ION, Putative uncharacterized protein Ta1305, SULFATE ION
著者Vinokur, J.M, Cascio, D, Sawaya, M.R, Bowie, J.U.
登録日2014-10-13
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases.
Protein Sci., 24, 2015
4RKZ
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BU of 4rkz by Molmil
Crystal Structure of Mevalonate-3-Kinase from Thermoplasma acidophilum (Mevalonate 3-Phosphate/ADP Bound)
分子名称: (3R)-5-hydroxy-3-methyl-3-(phosphonooxy)pentanoic acid, ADENOSINE-5'-DIPHOSPHATE, Putative uncharacterized protein Ta1305, ...
著者Vinokur, J.M, Cascio, D, Sawaya, M.R, Bowie, J.U.
登録日2014-10-14
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases.
Protein Sci., 24, 2015
5V5C
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BU of 5v5c by Molmil
VQIINK, Structure of the amyloid-spine from microtubule associated protein tau Repeat 2
分子名称: Microtubule-associated protein tau
著者Seidler, P.M, Sawaya, M.R, Rodriguez, J.A, Eisenberg, D.S, Cascio, D, Boyer, D.R.
登録日2017-03-14
公開日2018-02-07
最終更新日2024-03-13
実験手法ELECTRON CRYSTALLOGRAPHY (1.25 Å)
主引用文献Structure-based inhibitors of tau aggregation.
Nat Chem, 10, 2018
4QIV
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BU of 4qiv by Molmil
Crystal structure of hexameric microcomparment shell protein from Aeromonas hydrophila
分子名称: Bacterial microcompartments family protein
著者Pang, A.H, Sawaya, M.R, Yeates, T.O.
登録日2014-06-02
公開日2015-08-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a hexameric microcomparment protein from Aeromonas hydrophila
To be Published
4R0P
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BU of 4r0p by Molmil
Ifqins, an amyloid forming segment from human lysozyme spanning residues 56-61
分子名称: Lysozyme C
著者Sievers, S, Eisenberg, D.S, Sawaya, M.R.
登録日2014-08-01
公開日2014-12-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Structure-based design of functional amyloid materials.
J.Am.Chem.Soc., 136, 2014
4R0U
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BU of 4r0u by Molmil
Tgvtava, an amyloid forming segment from alpha synuclein, residues 72-78
分子名称: Alpha-synuclein
著者Ivanova, M.I, Eisenberg, D.S, Sawaya, M.R.
登録日2014-08-01
公開日2014-12-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Structure-based design of functional amyloid materials.
J.Am.Chem.Soc., 136, 2014
4RBV
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BU of 4rbv by Molmil
PduA K26A S40GSG mutant, from Salmonella enterica serovar Typhimurium LT2
分子名称: Propanediol utilization protein PduA, SULFATE ION
著者Chun, S, Sawaya, M.R, Yeates, T.O.
登録日2014-09-13
公開日2015-02-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Selective molecular transport through the protein shell of a bacterial microcompartment organelle.
Proc.Natl.Acad.Sci.USA, 112, 2015
5TXJ
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BU of 5txj by Molmil
Polymorphic form 1 of amyloid-beta derived peptide - IFAEDV
分子名称: amyloid-beta derived peptide
著者Sangwan, S, Sawaya, M.R, Eisenberg, D.
登録日2016-11-16
公開日2017-11-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Distal amyloid beta-protein fragments template amyloid assembly.
Protein Sci., 27, 2018
4QIE
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BU of 4qie by Molmil
Crystal Structure of PduA with edge mutation K26D
分子名称: GLYCEROL, Propanediol utilization protein PduA, SULFATE ION
著者Pang, A.H, Sawaya, M.R, Yeates, T.O.
登録日2014-05-30
公開日2015-06-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3501 Å)
主引用文献Crystal Structure of PduA with edge mutation K26D
To be Published
5TXD
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BU of 5txd by Molmil
Structure of amyloid-beta derived peptide - NKGAIF
分子名称: Amyloid beta A4 protein, PHOSPHATE ION
著者Sangwan, S, Sawaya, M.R, Eisenberg, D.
登録日2016-11-16
公開日2017-11-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.452 Å)
主引用文献Distal amyloid beta-protein fragments template amyloid assembly.
Protein Sci., 27, 2018
5TXH
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BU of 5txh by Molmil
Polymorphic form 2 of amyloid-beta derived peptide - IFAEDV
分子名称: IFAEDV, ISOPROPYL ALCOHOL
著者Sangwan, S, Sawaya, M.R, Eisenberg, D.
登録日2016-11-16
公開日2017-11-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Distal amyloid beta-protein fragments template amyloid assembly.
Protein Sci., 27, 2018
3Q9I
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BU of 3q9i by Molmil
LVFFA segment from Alzheimer's Amyloid-Beta displayed on 42-membered macrocycle scaffold, bromide derivative
分子名称: CHLORIDE ION, Cyclic pseudo-peptide LV(4BF)FA(ORN)(HAO)LK(ORN), GLYCEROL, ...
著者Liu, C, Sawaya, M.R, Eisenberg, D, Nowick, J.S, Cheng, P, Zheng, J.
登録日2011-01-07
公開日2011-06-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic beta-Sheet Mimics.
J.Am.Chem.Soc., 133, 2011
3SB8
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BU of 3sb8 by Molmil
Cu-mediated Dimer of T4 Lysozyme D61H/K65H by Synthetic Symmetrization
分子名称: COPPER (II) ION, Lysozyme
著者Soriaga, A.B, Laganowsky, A, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2011-06-03
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SER
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BU of 3ser by Molmil
Zn-mediated Polymer of Maltose-binding Protein K26H/K30H by Synthetic Symmetrization
分子名称: CALCIUM ION, CHLORIDE ION, Maltose-binding periplasmic protein, ...
著者Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2011-06-11
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SGN
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BU of 3sgn by Molmil
Bromoderivative-8 of amyloid-related segment of alphaB-crystallin residues 90-100
分子名称: Alpha-crystallin B chain
著者Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2011-06-15
公開日2012-03-21
実験手法X-RAY DIFFRACTION (2.807 Å)
主引用文献Atomic view of a toxic amyloid small oligomer.
Science, 335, 2012
3SEY
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BU of 3sey by Molmil
Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form II)
分子名称: ACETATE ION, GLYCEROL, Maltose-binding periplasmic protein, ...
著者Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2011-06-11
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SB6
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BU of 3sb6 by Molmil
Cu-mediated Dimer of T4 Lysozyme D61H/K65H/R76H/R80H by Synthetic Symmetrization
分子名称: CHLORIDE ION, COPPER (II) ION, Lysozyme
著者Soriaga, A.B, Laganowsky, A, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2011-06-03
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SB7
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BU of 3sb7 by Molmil
Cu-mediated Trimer of T4 Lysozyme D61H/K65H/R76H/R80H by Synthetic Symmetrization
分子名称: COPPER (II) ION, GLYCEROL, Lysozyme
著者Soriaga, A.B, Laganowsky, A, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2011-06-03
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SGM
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BU of 3sgm by Molmil
Bromoderivative-2 of amyloid-related segment of alphaB-crystallin residues 90-100
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-crystallin B chain
著者Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2011-06-15
公開日2012-03-21
実験手法X-RAY DIFFRACTION (1.7006 Å)
主引用文献Atomic view of a toxic amyloid small oligomer.
Science, 335, 2012
3SGR
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BU of 3sgr by Molmil
Tandem repeat of amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Tandem repeat of amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L
著者Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2011-06-15
公開日2012-03-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Atomic view of a toxic amyloid small oligomer.
Science, 335, 2012
3SB9
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BU of 3sb9 by Molmil
Cu-mediated Dimer of T4 Lysozyme R76H/R80H by Synthetic Symmetrization
分子名称: COPPER (II) ION, FORMIC ACID, Lysozyme
著者Soriaga, A.B, Laganowsky, A, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2011-06-03
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SEV
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BU of 3sev by Molmil
Zn-mediated Trimer of Maltose-binding Protein E310H/K314H by Synthetic Symmetrization
分子名称: CHLORIDE ION, Maltose-binding periplasmic protein, ZINC ION, ...
著者Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2011-06-11
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3Q27
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BU of 3q27 by Molmil
Cyrstal structure of human alpha-synuclein (32-57) fused to maltose binding protein (MBP)
分子名称: GLYCEROL, Maltose-binding periplasmic protein/alpha-synuclein chimeric protein, SULFATE ION, ...
著者Zhao, M, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2010-12-19
公開日2011-06-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.302 Å)
主引用文献Structures of segments of alpha-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation
Protein Sci., 20, 2011

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