4RKZ

Crystal Structure of Mevalonate-3-Kinase from Thermoplasma acidophilum (Mevalonate 3-Phosphate/ADP Bound)

Summary for 4RKZ

Entry DOI	10.2210/pdb4rkz/pdb
Related	4RKP 4RKS
Descriptor	Putative uncharacterized protein Ta1305, ADENOSINE-5'-DIPHOSPHATE, (3R)-5-hydroxy-3-methyl-3-(phosphonooxy)pentanoic acid, ... (5 entities in total)
Functional Keywords	mevalonate, mevalonate-3-kinase, mevalonate pyrophosphate decarboxylase, mevalonate diphosphate decarboxylase, mevalonic acid, mevalonate kinase, transferase
Biological source	Thermoplasma acidophilum
Total number of polymer chains	2
Total formula weight	75824.64
Authors	Vinokur, J.M.,Cascio, D.,Sawaya, M.R.,Bowie, J.U. (deposition date: 2014-10-14, release date: 2014-12-10, Last modification date: 2023-09-20)
Primary citation	Vinokur, J.M.,Korman, T.P.,Sawaya, M.R.,Collazo, M.,Cascio, D.,Bowie, J.U. Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases. Protein Sci., 24:212-220, 2015 Cited by PubMed: 25422158 DOI: 10.1002/pro.2607 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation