4RKZ

Crystal Structure of Mevalonate-3-Kinase from Thermoplasma acidophilum (Mevalonate 3-Phosphate/ADP Bound)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Putative uncharacterized protein Ta1305	polymer	337	37278.5	2	UniProt (Q9HIN1) Pfam (PF22700) Pfam (PF21433)	Thermoplasma acidophilum	Mevalonate-3-Kinase
2	C (A)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
3	D, F (A, B)	(3R)-5-hydroxy-3-methyl-3-(phosphonooxy)pentanoic acid	non-polymer		228.1	2	Chemie (3S4)
4	E, G, H, I (A, B)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
5	J, K (A, B)	water	water		18.0	40	Chemie (HOH)

Sequence modifications

A, B: 1 - 318 (UniProt: Q9HIN1)

PDB	External Database	Details
Met -18	-	expression tag
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	74556.9
Non-Polymers*	Number of molecules	7
	Total formula weight	1267.7
All*	Total formula weight	75824.6

*Water molecules are not included.