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8HK2
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BU of 8hk2 by Molmil
C3aR-Gi-C3a protein complex
分子名称: C3a anaphylatoxin, C3a anaphylatoxin chemotactic receptor, CHOLESTEROL, ...
著者Wang, Y, Liu, W, Xu, Y, Zhuang, Y, Xu, H.E.
登録日2022-11-24
公開日2023-05-10
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Revealing the signaling of complement receptors C3aR and C5aR1 by anaphylatoxins.
Nat.Chem.Biol., 19, 2023
3ML9
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BU of 3ml9 by Molmil
Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04691502 through Structure Based Drug Design
分子名称: 2-amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7(8H)-one, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
著者Knighton, D.R.
登録日2010-04-16
公開日2010-06-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design.
ACS Med Chem Lett, 4, 2013
3ML8
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BU of 3ml8 by Molmil
Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04691502 through Structure Based Drug Design
分子名称: 8-cyclopentyl-6-[3-(hydroxymethyl)phenyl]-4-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
著者Knighton, D.R.
登録日2010-04-16
公開日2010-06-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design.
ACS Med Chem Lett, 4, 2013
6IIN
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BU of 6iin by Molmil
USP14 catalytic domain with IU1-248
分子名称: 4-{3-[(4-hydroxypiperidin-1-yl)acetyl]-2,5-dimethyl-1H-pyrrol-1-yl}benzonitrile, Ubiquitin carboxyl-terminal hydrolase 14
著者Mei, Z.Q, Wang, J.W, Wang, F, Wang, Y.W.
登録日2018-10-07
公開日2018-12-19
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade.
Cell Res., 28, 2018
6IIM
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BU of 6iim by Molmil
USP14 catalytic domain with IU1-206
分子名称: 1-[1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(4-hydroxypiperidin-1-yl)ethan-1-one, Ubiquitin carboxyl-terminal hydrolase 14
著者Mei, Z.Q, Wang, J.W, Wang, F, Wang, Y.W.
登録日2018-10-07
公開日2018-12-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade.
Cell Res., 28, 2018
6IIL
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BU of 6iil by Molmil
USP14 catalytic domain bind to IU1-47
分子名称: 1-[1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(piperidin-1-yl)ethan-1-one, Ubiquitin carboxyl-terminal hydrolase 14
著者Mei, Z.Q, Wang, Y.W, Wang, F, Wang, J.W, He, W, Ding, S, Li, J.W.
登録日2018-10-07
公開日2018-12-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade.
Cell Res., 28, 2018
7WEC
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BU of 7wec by Molmil
SARS-CoV-2 Omicron variant spike protein with three XGv347 Fabs binding to three closed state RBDs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Wang, X, Wang, L.
登録日2021-12-23
公開日2022-05-04
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants.
Nature, 603, 2022
7WE7
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BU of 7we7 by Molmil
SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv282
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 282, ...
著者Wang, X, Wang, L.
登録日2021-12-23
公開日2022-05-04
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants.
Nature, 603, 2022
7WEE
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BU of 7wee by Molmil
SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv265
分子名称: Spike glycoprotein, The heavy chain of Fab XGv265, The light chain of Fab XGv265
著者Wang, X, Wang, L.
登録日2021-12-23
公開日2022-05-04
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants.
Nature, 603, 2022
7WEF
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BU of 7wef by Molmil
SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv289
分子名称: Spike protein S1, The heavy chain of Fab XGv289, The light chain of Fab XGv289
著者Wang, X, Wang, L.
登録日2021-12-23
公開日2022-05-04
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants.
Nature, 603, 2022
7WEB
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BU of 7web by Molmil
SARS-CoV-2 Omicron variant spike protein with two XGv347 binding to two open state RBDs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Wang, X, Wang, L.
登録日2021-12-23
公開日2022-05-04
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants.
Nature, 603, 2022
7WE9
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BU of 7we9 by Molmil
SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv289
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Wang, X, Wang, L.
登録日2021-12-23
公開日2022-05-04
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants.
Nature, 603, 2022
3QE7
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BU of 3qe7 by Molmil
Crystal Structure of Uracil Transporter--UraA
分子名称: URACIL, Uracil permease, nonyl beta-D-glucopyranoside
著者Lu, F.R, Li, S, Yan, N.
登録日2011-01-20
公開日2011-03-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.781 Å)
主引用文献Structure and mechanism of the uracil transporter UraA
Nature, 472, 2011
7WLC
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BU of 7wlc by Molmil
SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv282
分子名称: Heavy chain of XGv282, Light chain of XGv282, Spike protein S1
著者Wang, X, Wang, L.
登録日2022-01-13
公開日2022-04-13
最終更新日2022-05-04
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants.
Nature, 603, 2022
7WED
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BU of 7wed by Molmil
SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv347
分子名称: Spike protein S1, The heavy chain of Fab XGv347, The light chain of Fab XGv347
著者Wang, X, Wang, L.
登録日2021-12-23
公開日2022-04-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants.
Nature, 603, 2022
7WEA
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BU of 7wea by Molmil
SARS-CoV-2 Omicron variant spike protein in complex with two XGv347 binding to one close state RBD and one open state RBD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Wang, X, Wang, L.
登録日2021-12-23
公開日2022-05-04
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants.
Nature, 603, 2022
7WE8
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BU of 7we8 by Molmil
SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv265
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 265, ...
著者Wang, X, Wang, L.
登録日2021-12-23
公開日2022-05-04
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants.
Nature, 603, 2022
8GTD
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BU of 8gtd by Molmil
Cryo-EM model of the marine siphophage vB_DshS-R4C portal-adaptor complex
分子名称: Head-to-tail joining protein, Portal protein
著者Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N.
登録日2022-09-08
公開日2023-07-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structure and proposed DNA delivery mechanism of a marine roseophage.
Nat Commun, 14, 2023
8GTB
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BU of 8gtb by Molmil
Cryo-EM structure of the marine siphophage vB_DshS-R4C tail tube protein
分子名称: Major tail protein
著者Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N.
登録日2022-09-08
公開日2023-07-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Structure and proposed DNA delivery mechanism of a marine roseophage.
Nat Commun, 14, 2023
8GTC
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BU of 8gtc by Molmil
Cryo-EM model of the marine siphophage vB_DshS-R4C baseplate-tail complex
分子名称: Distal tail protein, Hub protein, Major tail protein, ...
著者Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N.
登録日2022-09-08
公開日2023-07-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structure and proposed DNA delivery mechanism of a marine roseophage.
Nat Commun, 14, 2023
8GTA
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BU of 8gta by Molmil
Cryo-EM structure of the marine siphophage vB_Dshs-R4C capsid
分子名称: Major capsid protein
著者Sun, H, Huang, Y, Zheng, Q, Li, S, Zhang, R, Xia, N.
登録日2022-09-07
公開日2023-07-12
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.63 Å)
主引用文献Structure and proposed DNA delivery mechanism of a marine roseophage.
Nat Commun, 14, 2023
8GTF
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BU of 8gtf by Molmil
Cryo-EM model of the marine siphophage vB_DshS-R4C stopper-terminator complex
分子名称: Head-to-tail joining protein, Major tail protein, Terminator protein
著者Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N.
登録日2022-09-08
公開日2023-07-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献Structure and proposed DNA delivery mechanism of a marine roseophage.
Nat Commun, 14, 2023
5H7V
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BU of 5h7v by Molmil
Structure of full-length extracellular domain of HAI-1 at pH 4.6
分子名称: Kunitz-type protease inhibitor 1
著者Liu, M, Huang, M.
登録日2016-11-21
公開日2017-03-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.82 Å)
主引用文献The crystal structure of a multidomain protease inhibitor (HAI-1) reveals the mechanism of its auto-inhibition
J. Biol. Chem., 292, 2017
8X17
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BU of 8x17 by Molmil
Cryo-EM structure of adenosine receptor A3AR bound to CF102
分子名称: Adenosine receptor A3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Cai, H, Xu, Y, Xu, H.E.
登録日2023-11-06
公開日2024-04-24
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Cryo-EM structures of adenosine receptor A 3 AR bound to selective agonists.
Nat Commun, 15, 2024
8X16
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BU of 8x16 by Molmil
Cryo-EM structure of adenosine receptor A3AR bound to CF101
分子名称: Adenosine receptor A3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Cai, H, Xu, Y, Xu, H.E.
登録日2023-11-06
公開日2024-04-24
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Cryo-EM structures of adenosine receptor A 3 AR bound to selective agonists.
Nat Commun, 15, 2024

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