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Tilapia Lake Virus polymerase in vRNA pre-initiation state mode B (transcriptase conformation)
分子名称:	5' vRNA end - vRNA loop (40-mer), Polymerase acidic protein (PA-like), Putative PB1, ...
著者	Arragain, B, Cusack, S.
登録日	2023-07-13
公開日	2023-12-27
実験手法	ELECTRON MICROSCOPY (2.59 Å)
主引用文献	Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023

8PSU

Tilapia Lake Virus polymerase in vRNA pre-initiation state mode A (core only)
分子名称:	5' vRNA end - vRNA loop (40-mer), Polymerase acidic protein (PA-like), Putative PB1, ...
著者	Arragain, B, Cusack, S.
登録日	2023-07-13
公開日	2023-12-27
実験手法	ELECTRON MICROSCOPY (3.18 Å)
主引用文献	Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023

8PSO

Tilapia Lake Virus polymerase in vRNA initiation state (core only)
分子名称:	5' vRNA end - vRNA loop (40-mer), DNA (5'-D(*(CTP))-3'), MAGNESIUM ION, ...
著者	Arragain, B, Cusack, S.
登録日	2023-07-13
公開日	2023-12-27
実験手法	ELECTRON MICROSCOPY (2.4 Å)
主引用文献	Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023

8PSQ

Tilapia Lake Virus polymerase in cRNA pre-initiation state mode A (core only)
分子名称:	5' cRNA end - cRNA loop (40-mer), MAGNESIUM ION, Polymerase acidic protein (PA-like), ...
著者	Arragain, B, Cusack, S.
登録日	2023-07-13
公開日	2023-12-27
実験手法	ELECTRON MICROSCOPY (2.65 Å)
主引用文献	Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023

8PTJ

Tilapia Lake Virus polymerase in vRNA pre-initiation state mode B (close core \| partial replicase conformation)
分子名称:	3' vRNA end - vRNA loop (40-mer), Polymerase acidic protein (PA-like), Putative PB1, ...
著者	Arragain, B, Cusack, S.
登録日	2023-07-14
公開日	2023-12-27
実験手法	ELECTRON MICROSCOPY (2.86 Å)
主引用文献	Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023

8PT6

Tilapia Lake Virus polymerase in vRNA initiation state (replicase conformation)
分子名称:	5' vRNA end - vRNA loop (40-mer), DNA (5'-D(*(CTP))-3'), MAGNESIUM ION, ...
著者	Arragain, B, Cusack, S.
登録日	2023-07-13
公開日	2023-12-27
最終更新日	2024-03-13
実験手法	ELECTRON MICROSCOPY (3.03 Å)
主引用文献	Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023

8PSS

Tilapia Lake Virus polymerase in cRNA pre-initiation state mode B (core-endo only)
分子名称:	5' cRNA end - cRNA loop (40-mer), MAGNESIUM ION, Polymerase acidic protein (PA-like), ...
著者	Arragain, B, Cusack, S.
登録日	2023-07-13
公開日	2023-12-27
実験手法	ELECTRON MICROSCOPY (2.83 Å)
主引用文献	Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023

8PSZ

Tilapia Lake Virus polymerase in vRNA elongation state with additional mode B promoter (transcriptase conformation)
分子名称:	5' vRNA end - vRNA loop (40-mer), MAGNESIUM ION, Polymerase acidic protein (PA-like), ...
著者	Arragain, B, Cusack, S.
登録日	2023-07-13
公開日	2024-01-10
実験手法	ELECTRON MICROSCOPY (2.42 Å)
主引用文献	Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023

8QZ8

Tilapia Lake Virus polymerase in vRNA pre-termination state (transcriptase conformation)
分子名称:	MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Polymerase acidic protein (PA-like), ...
著者	Arragain, B, Cusack, S.
登録日	2023-10-26
公開日	2023-12-27
実験手法	ELECTRON MICROSCOPY (3.13 Å)
主引用文献	Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023

3V11

Structure of the ternary initiation complex AIF2:GDPNP:methionylated initiator TRNA
分子名称:	Initiator tRNA, MAGNESIUM ION, METHIONINE, ...
著者	Mechulam, Y, Schmitt, E.
登録日	2011-12-09
公開日	2012-03-28
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (5 Å)
主引用文献	Structure of the ternary initiation complex aIF2-GDPNP-methionylated initiator tRNA. Nat.Struct.Mol.Biol., 19, 2012

4NLB

Crystal structure of the catalytic core of RRP6 from Trypanosoma brucei
分子名称:	Ribosomal RNA processing protein 6
著者	Barbosa, R.L, Guimaraes, B.G.
登録日	2013-11-14
公開日	2014-03-26
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	RRP6 from Trypanosoma brucei: Crystal Structure of the Catalytic Domain, Association with EAP3 and Activity towards Structured and Non-Structured RNA Substrates Plos One, 9, 2014

4NLC

Crystal structure of the catalytic core of RRP6 from Trypanosoma brucei, mutant C496S
分子名称:	DI(HYDROXYETHYL)ETHER, Ribosomal RNA processing protein 6
著者	Barbosa, R.L, Guimaraes, B.G.
登録日	2013-11-14
公開日	2014-03-26
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (2.15 Å)
主引用文献	RRP6 from Trypanosoma brucei: Crystal Structure of the Catalytic Domain, Association with EAP3 and Activity towards Structured and Non-Structured RNA Substrates Plos One, 9, 2014

4OZF

JR5.1 protein complex
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DQ alpha 1 chain, ...
著者	Petersen, J, Reid, H.H, Rossjohn, J.
登録日	2014-02-15
公開日	2014-04-16
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease. Nat.Struct.Mol.Biol., 21, 2014

4OZH

S16 protein complex
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Gliadin-alpha2 peptide, ...
著者	Petersen, J, Reid, H.H, Rossjohn, J.
登録日	2014-02-16
公開日	2014-04-16
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease. Nat.Struct.Mol.Biol., 21, 2014

4OZI

S2 protein complex
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HLA class II histocompatibility antigen, ...
著者	Petersen, J, Reid, H.H, Rossjohn, J.
登録日	2014-02-16
公開日	2014-04-16
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (3.2 Å)
主引用文献	T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease. Nat.Struct.Mol.Biol., 21, 2014

4OZG

D2 protein complex
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者	Petersen, J, Reid, H.H, Rossjohn, J.
登録日	2014-02-16
公開日	2014-04-16
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease. Nat.Struct.Mol.Biol., 21, 2014

3CQE

Wee1 kinase complex with inhibitor PD074291
分子名称:	8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole-7-carboxamide, CHLORIDE ION, GLYCEROL, ...
著者	Squire, C.J, Baker, E.N.
登録日	2008-04-02
公開日	2009-02-24
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Structural Determinants of Wee1 Inhibitor Selectivity To be Published

3CR0

Wee1 kinase complex with inhibitor PD259_809
分子名称:	4-(2-chlorophenyl)-8-(2-hydroxyethyl)-6-methylpyrrolo[3,4-e]indole-1,3(2H,6H)-dione, CHLORIDE ION, GLYCEROL, ...
著者	Squire, C.J, Baker, E.N.
登録日	2008-04-03
公開日	2009-02-24
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Structural determinants of Wee1 inhibitor selectivity To be Published

4BN1

Crystal structure of V174M mutant of Aurora-A kinase
分子名称:	ADENOSINE-5'-DIPHOSPHATE, AURORA KINASE A, CALCIUM ION
著者	Bibby, R.A, Bayliss, R.
登録日	2013-05-13
公開日	2014-03-26
最終更新日	2023-12-20
実験手法	X-RAY DIFFRACTION (2.499 Å)
主引用文献	Insights Into Aurora-A Kinase Activation Using Unnatural Amino Acids Incorporated by Chemical Modification. Acs Chem.Biol., 8, 2013

4BUQ

Crystal structure of wild type FimH lectin domain in complex with heptyl alpha-D-mannopyrannoside
分子名称:	FIMH, heptyl alpha-D-mannopyranoside
著者	Rabbani, S, Bouckaert, J, Zalewski, A, Preston, R, Eid, S, Thompson, A, Puorger, C, Glockshuber, R, Ernst, B.
登録日	2013-06-23
公開日	2014-02-19
最終更新日	2023-12-20
実験手法	X-RAY DIFFRACTION (2.199 Å)
主引用文献	Validation of Reactivity Descriptors to Assess the Aromatic Stacking within the Tyrosine Gate of Fimh Acs Med.Chem.Lett., 4, 2013

2KIN

KINESIN (MONOMERIC) FROM RATTUS NORVEGICUS
分子名称:	ADENOSINE-5'-DIPHOSPHATE, KINESIN, SULFATE ION
著者	Sack, S, Muller, J, Kozielski, F, Marx, A, Thormahlen, M, Biou, V, Mandelkow, E.-M, Brady, S.T, Mandelkow, E.
登録日	1997-04-28
公開日	1998-04-08
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	X-ray structure of motor and neck domains from rat brain kinesin. Biochemistry, 36, 1997

3GDN

Almond hydroxynitrile lyase in complex with benzaldehyde
分子名称:	(2R)-hydroxy(phenyl)ethanenitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者	Dreveny, I, Gruber, K, Kratky, C.
登録日	2009-02-24
公開日	2009-03-24
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (1.67 Å)
主引用文献	Substrate binding in the FAD-dependent hydroxynitrile lyase from almond provides insight into the mechanism of cyanohydrin formation and explains the absence of dehydrogenation activity. Biochemistry, 48, 2009

1OLA

THE STRUCTURAL BASIS OF MULTISPECIFICITY IN THE OLIGOPEPTIDE-BINDING PROTEIN OPPA
分子名称:	OLIGO-PEPTIDE BINDING PROTEIN, PEPTIDE VAL-LYS-PRO-GLY, URANYL (VI) ION
著者	Tame, J, Wilkinson, A.J.
登録日	1994-04-26
公開日	1994-07-31
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	The structural basis of sequence-independent peptide binding by OppA protein. Science, 264, 1994

1OLC

OLIGO-PEPTIDE BINDING PROTEIN (OPPA) COMPLEXED WITH LYS-LYS-LYS-ALA
分子名称:	LYS-LYS-LYS-ALA, OLIGO-PEPTIDE BINDING PROTEIN, URANYL (VI) ION
著者	Tame, J, Wilkinson, A.J.
登録日	1995-09-10
公開日	1996-01-29
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	The crystal structures of the oligopeptide-binding protein OppA complexed with tripeptide and tetrapeptide ligands. Structure, 3, 1995

1QKA

OLIGO-PEPTIDE BINDING PROTEIN (OPPA) COMPLEXED WITH KRK
分子名称:	LYS-ARG-LYS, PERIPLASMIC OLIGOPEPTIDE-BINDING PROTEIN, URANYL (VI) ION
著者	Tame, J.R.H, Wilkinson, A.J.
登録日	1999-07-14
公開日	1999-09-09
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Crystallographic and Calorimetric Analysis of Peptide Binding to Oppa Protein J.Mol.Biol., 291, 1999

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