4BN1

Crystal structure of V174M mutant of Aurora-A kinase

Summary for 4BN1

Entry DOI	10.2210/pdb4bn1/pdb
Descriptor	AURORA KINASE A, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... (4 entities in total)
Functional Keywords	transferase, protein kinase, mitosis
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome: O14965
Total number of polymer chains	1
Total formula weight	33648.17
Authors	Bibby, R.A.,Bayliss, R. (deposition date: 2013-05-13, release date: 2014-03-26, Last modification date: 2023-12-20)
Primary citation	Rowan, F.C.,Richards, M.,Bibby, R.A.,Thompson, A.,Bayliss, R.,Blagg, J. Insights Into Aurora-A Kinase Activation Using Unnatural Amino Acids Incorporated by Chemical Modification. Acs Chem.Biol., 8:2184-, 2013 Cited by PubMed: 23924325 DOI: 10.1021/CB400425T PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.499 Å)

Structure validation