4BN1
Crystal structure of V174M mutant of Aurora-A kinase
Summary for 4BN1
Entry DOI | 10.2210/pdb4bn1/pdb |
Descriptor | AURORA KINASE A, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | transferase, protein kinase, mitosis |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome: O14965 |
Total number of polymer chains | 1 |
Total formula weight | 33648.17 |
Authors | Bibby, R.A.,Bayliss, R. (deposition date: 2013-05-13, release date: 2014-03-26, Last modification date: 2023-12-20) |
Primary citation | Rowan, F.C.,Richards, M.,Bibby, R.A.,Thompson, A.,Bayliss, R.,Blagg, J. Insights Into Aurora-A Kinase Activation Using Unnatural Amino Acids Incorporated by Chemical Modification. Acs Chem.Biol., 8:2184-, 2013 Cited by PubMed: 23924325DOI: 10.1021/CB400425T PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.499 Å) |
Structure validation
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