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6BPH
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BU of 6bph by Molmil
Crystal structure of the chromodomain of RBBP1
分子名称: AT-rich interactive domain-containing protein 4A, UNKNOWN ATOM OR ION
著者Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-11-23
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of chromo barrel domain of RBBP1.
Biochem. Biophys. Res. Commun., 496, 2018
3NA9
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BU of 3na9 by Molmil
Crystal structure of Fab15
分子名称: ACETATE ION, Fab15 heavy chain, Fab15 light chain, ...
著者Luo, J.
登録日2010-06-01
公開日2010-08-18
最終更新日2021-03-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Co-evolution of antibody stability and Vk CDR-L3 canonical structure
To be Published
6KUE
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BU of 6kue by Molmil
The structure of BioZ from Agrobacterium tumefaciens
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase III
著者Ouyang, S, Hongxin, G, Sitao, Z.
登録日2019-09-01
公開日2020-09-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.992 Å)
主引用文献Biochemical and structural characterization of the BioZ enzyme engaged in bacterial biotin synthesis pathway.
Nat Commun, 12, 2021
5ZOI
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BU of 5zoi by Molmil
Crystal Structure of alpha1,3-Fucosyltransferase
分子名称: Alpha-(1,3)-fucosyltransferase FucT, [[(2S,3R,4S,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4S,5R,6R)-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl] hydrogen phosphate
著者Tan, Y, Yang, G.
登録日2018-04-13
公開日2019-06-26
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Directed evolution of an alpha 1,3-fucosyltransferase using a single-cell ultrahigh-throughput screening method.
Sci Adv, 5, 2019
7EU0
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BU of 7eu0 by Molmil
The cryo-EM structure of A. thaliana Pol IV-RDR2 backtracked complex
分子名称: DNA (33-MER), DNA (5'-D(*CP*TP*GP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*GP*AP*GP*TP*G)-3'), DNA-directed RNA polymerase IV subunit 1, ...
著者Fang, C.L, Wu, X.X, Huang, K, Zhang, Y.
登録日2021-05-15
公開日2021-12-29
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Pol IV and RDR2: A two-RNA-polymerase machine that produces double-stranded RNA.
Science, 374, 2021
7EU1
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BU of 7eu1 by Molmil
The cryo-EM structure of A. thaliana Pol IV-RDR2 holoenzyme
分子名称: DNA-directed RNA polymerase IV subunit 1, DNA-directed RNA polymerases II and IV subunit 5A, DNA-directed RNA polymerases II, ...
著者Fang, C.L, Wu, X.X, Huang, K, Zhang, Y.
登録日2021-05-15
公開日2021-12-29
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Pol IV and RDR2: A two-RNA-polymerase machine that produces double-stranded RNA.
Science, 374, 2021
7F0R
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BU of 7f0r by Molmil
Cryo-EM structure of Pseudomonas aeruginosa SutA transcription activation complex
分子名称: DNA (70-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者He, D.W, You, L.L, Zhang, Y.
登録日2021-06-06
公開日2022-07-27
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding.
Nat Commun, 13, 2022
6JBQ
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BU of 6jbq by Molmil
CryoEM structure of Escherichia coli sigmaE transcription initiation complex containing 5nt of RNA
分子名称: DNA (48-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Fang, C.L, Zhang, Y.
登録日2019-01-26
公開日2019-05-29
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
6J9E
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BU of 6j9e by Molmil
Cryo-EM structure of Xanthomonos oryzae transcription elongation complex with NusA and the bacteriophage protein P7
分子名称: 45L, DNA (29-MER), DNA-directed RNA polymerase subunit alpha, ...
著者You, L.L, Zhang, Y.
登録日2019-01-22
公開日2019-07-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Structural basis for transcription antitermination at bacterial intrinsic terminator.
Nat Commun, 10, 2019
6LDI
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BU of 6ldi by Molmil
The cryo-EM structure of E. coli CueR transcription activation complex
分子名称: DNA (50-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Fang, C.L, Zhang, Y.
登録日2019-11-21
公開日2020-09-30
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献CueR activates transcription through a DNA distortion mechanism.
Nat.Chem.Biol., 17, 2021
6JCX
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BU of 6jcx by Molmil
Mycobacterium tuberculosis transcription initiation complex with ECF sigma factor sigma H and 6nt RNA
分子名称: DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Li, L, Zhang, Y.
登録日2019-01-30
公開日2019-05-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.903 Å)
主引用文献Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
6JCY
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BU of 6jcy by Molmil
Mycobacterium tuberculosis RNA polymerase transcription initiation open complex with a chimeric ECF sigma factor sigH/E
分子名称: DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Li, L, Zhang, Y.
登録日2019-01-30
公開日2019-05-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.106 Å)
主引用文献Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
6KJ6
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BU of 6kj6 by Molmil
cryo-EM structure of Escherichia coli Crl transcription activation complex
分子名称: DNA (51-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Xu, J, Zhang, Y.
登録日2019-07-21
公開日2020-01-01
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Crl activates transcription by stabilizing active conformation of the master stress transcription initiation factor.
Elife, 8, 2019
6J9F
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BU of 6j9f by Molmil
Cryo-EM structure of Xanthomonos oryzae transcription elongation complex with the bacteriophage protein P7
分子名称: 45L, DNA (29-MER), DNA-directed RNA polymerase subunit alpha, ...
著者You, L.L, Zhang, Y.
登録日2019-01-22
公開日2019-07-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.95 Å)
主引用文献Structural basis for transcription antitermination at bacterial intrinsic terminator.
Nat Commun, 10, 2019
5CCU
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BU of 5ccu by Molmil
Crystal structure of endoglycoceramidase I from Rhodococ-cus equi
分子名称: 1,2-ETHANEDIOL, Putative secreted endoglycosylceramidase, SODIUM ION
著者Chen, L.
登録日2015-07-02
公開日2015-09-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structural Insights into the Broad Substrate Specificity of a Novel Endoglycoceramidase I Belonging to a New Subfamily of GH5 Glycosidases
J. Biol. Chem., 292, 2017
4G34
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BU of 4g34 by Molmil
Crystal Structure of GSK6924 Bound to PERK (R587-R1092, delete A660-T867) at 2.70 A Resolution
分子名称: 1-[5-(4-aminothieno[3,2-c]pyridin-3-yl)-2,3-dihydro-1H-indol-1-yl]-2-phenylethanone, Eukaryotic translation initiation factor 2-alpha kinase 3
著者Gampe, R.T, Axten, J.M.
登録日2012-07-13
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK).
J.Med.Chem., 55, 2012
4G31
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BU of 4g31 by Molmil
Crystal Structure of GSK6414 Bound to PERK (R587-R1092, delete A660-T867) at 2.28 A Resolution
分子名称: 1-[5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone, Eukaryotic translation initiation factor 2-alpha kinase 3, GLYCEROL
著者Gampe, R.T, Axten, J.M.
登録日2012-07-13
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK).
J.Med.Chem., 55, 2012
6JYZ
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BU of 6jyz by Molmil
Crystal structure of endogalactoceramidase
分子名称: 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ISOPROPYL ALCOHOL, ...
著者Liuqing, C, Yan, F.
登録日2019-04-29
公開日2019-10-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structure of an endogalactosylceramidase from Rhodococcus hoagii 103S reveals the molecular basis of its substrate specificity.
J.Struct.Biol., 208, 2019
4FWI
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BU of 4fwi by Molmil
Crystal structure of the nucleotide-binding domain of a dipeptide ABC transporter
分子名称: ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Li, X, Ge, J, Yang, M, Wang, N.
登録日2012-07-01
公開日2013-01-30
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.892 Å)
主引用文献Structure of the nucleotide-binding domain of a dipeptide ABC transporter reveals a novel iron-sulfur cluster-binding domain
Acta Crystallogr.,Sect.D, 69, 2013
2ZW0
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BU of 2zw0 by Molmil
Crystal structure of a Streptococcal protein G B1 mutant
分子名称: Protein LG, SULFATE ION
著者Watanabe, H, Matsumaru, H, Odahara, T, Suto, K, Honda, S.
登録日2008-11-26
公開日2009-03-03
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Optimizing pH response of affinity between protein G and IgG Fc: how electrostatic modulations affect protein-protein interactions.
J.Biol.Chem., 284, 2009
5EKU
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BU of 5eku by Molmil
Crystal Structure of Trypanosoma Brucei Protein Arginine Methyltransferase PRMT7 in complex with S-Adenosyl-L-homocysteine
分子名称: Arginine N-methyltransferase, putative, S-ADENOSYL-L-HOMOCYSTEINE
著者Debler, E.W, Stavropoulos, P.
登録日2015-11-04
公開日2016-05-18
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献A glutamate/aspartate switch controls product specificity in a protein arginine methyltransferase.
Proc.Natl.Acad.Sci.USA, 113, 2016
5EWI
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BU of 5ewi by Molmil
Crystal Structure of the Human Fab VRC38.01, an HIV-1 V1V2-Directed Neutralizing Antibody Isolated from Donor N90
分子名称: VRC38.01 Heavy Chain, VRC38.01 Light Chain
著者Gorman, J, Kwong, P.D.
登録日2015-11-20
公開日2016-11-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5996 Å)
主引用文献Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop.
Immunity, 46, 2017
2ZW1
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BU of 2zw1 by Molmil
Crystal structure of a Streptococcal protein G B1 mutant
分子名称: Protein LG
著者Watanabe, H, Matsumaru, H, Odahara, T, Suto, K, Honda, S.
登録日2008-11-26
公開日2009-03-03
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Optimizing pH response of affinity between protein G and IgG Fc: how electrostatic modulations affect protein-protein interactions.
J.Biol.Chem., 284, 2009
3T9N
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BU of 3t9n by Molmil
Crystal structure of a membrane protein
分子名称: DODECYL-BETA-D-MALTOSIDE, Small-conductance mechanosensitive channel
著者Yang, M, Zhang, X, Ge, J, Wang, J.
登録日2011-08-03
公開日2012-10-31
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.456 Å)
主引用文献Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance
Proc.Natl.Acad.Sci.USA, 109, 2012
3UDC
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BU of 3udc by Molmil
Crystal structure of a membrane protein
分子名称: Small-conductance mechanosensitive channel, C-terminal peptide from Small-conductance mechanosensitive channel
著者Li, W, Ge, J, Yang, M.
登録日2011-10-28
公開日2012-10-31
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.355 Å)
主引用文献Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance
Proc.Natl.Acad.Sci.USA, 109, 2012

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