3B3T
| Crystal structure of the D118N mutant of the aminopeptidase from Vibrio proteolyticus | 分子名称: | Bacterial leucyl aminopeptidase, ISOLEUCINE, SODIUM ION, ... | 著者 | Ataie, N.J, Hoang, Q.Q, Zahniser, M.P.D, Milne, A, Petsko, G.A, Ringe, D. | 登録日 | 2007-10-22 | 公開日 | 2007-11-27 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | 主引用文献 | Zinc coordination geometry and ligand binding affinity: the structural and kinetic analysis of the second-shell serine 228 residue and the methionine 180 residue of the aminopeptidase from Vibrio proteolyticus. Biochemistry, 47, 2008
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2BGE
| Structure-based design of Protein Tyrosine Phosphatase-1B Inhibitors | 分子名称: | 1,2,5-THIADIAZOLIDIN-3-ONE-1,1-DIOXIDE, PROTEIN-TYROSINE PHOSPHATASE NON-RECEPTOR TYPE 1 | 著者 | Black, E, Breed, J, Breeze, A.L, Embrey, K, Garcia, R, Gero, T.W, Godfrey, L, Kenny, P.W, Morley, A.D, Minshull, C.A, Pannifer, A.D, Read, J, Rees, A, Russell, D.J, Toader, D, Tucker, J. | 登録日 | 2004-12-21 | 公開日 | 2005-05-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure-Based Design of Protein Tyrosine Phosphatase-1B Inhibitors Bioorg.Med.Chem.Lett., 15, 2005
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3B2C
| Crystal structure of the collagen triple helix model [{PRO-HYP(R)-GLY}4-{HYP(S)-Pro-GLY}2-{PRO-HYP(R)-GLY}4]3 | 分子名称: | Collagen-like peptide | 著者 | Motooka, D, Kawahara, K, Nakamura, S, Doi, M, Nishi, Y, Nishiuchi, Y, Nakazawa, T, Yoshida, T, Ohkubo, T, Kobayashi, Y, Kang, Y.K, Uchiyama, S. | 登録日 | 2011-07-26 | 公開日 | 2012-04-04 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | The triple helical structure and stability of collagen model peptide with 4(S)-hydroxyprolyl-pro-gly units Biopolymers, 98, 2011
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3UID
| Crystal Structure of Protein Ms6760 from Mycobacterium smegmatis | 分子名称: | Putative uncharacterized protein | 著者 | Bajaj, R.A, Miallau, L, Cascio, D, Arbing, M, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2011-11-04 | 公開日 | 2011-11-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.571 Å) | 主引用文献 | Crystal structure of the toxin Msmeg_6760, the structural homolog of Mycobacterium tuberculosis Rv2035, a novel type II toxin involved in the hypoxic response. Acta Crystallogr F Struct Biol Commun, 72, 2016
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2YFN
| galactosidase domain of alpha-galactosidase-sucrose kinase, AgaSK | 分子名称: | 1,2-ETHANEDIOL, ALPHA-GALACTOSIDASE-SUCROSE KINASE AGASK, GLYCEROL, ... | 著者 | Sulzenbacher, G, Bruel, L, Tison-Cervera, M, Pujol, A, Nicoletti, C, Perrier, J, Galinier, A, Ropartz, D, Fons, M, Pompeo, F, Giardina, T. | 登録日 | 2011-04-07 | 公開日 | 2011-09-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Agask, a Bifunctional Enzyme from the Human Microbiome Coupling Galactosidase and Kinase Activities J.Biol.Chem., 286, 2011
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8WR8
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8WSW
| The Crystal Structure of LIMK2a from Biortus | 分子名称: | 1,2-ETHANEDIOL, LIM domain kinase 2, ~{N}-[5-[2-[2,6-bis(chloranyl)phenyl]-5-[bis(fluoranyl)methyl]pyrazol-3-yl]-1,3-thiazol-2-yl]-2-methyl-propanamide | 著者 | Wang, F, Cheng, W, Yuan, Z, Lin, D, Pan, W. | 登録日 | 2023-10-17 | 公開日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The Crystal Structure of LIMK2a from Biortus. To Be Published
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7ZPK
| Mammalian Dicer in the "pre-dicing state" with pre-miR-15a substrate and TARBP2 subunit | 分子名称: | 59-nt precursor of miR-15a, Endoribonuclease Dicer, RISC-loading complex subunit TARBP2 | 著者 | Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J. | 登録日 | 2022-04-27 | 公開日 | 2022-11-16 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.81 Å) | 主引用文献 | Structural and functional basis of mammalian microRNA biogenesis by Dicer. Mol.Cell, 82, 2022
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7ZN7
| Cryo-EM structure of RCMV-E E27 bound to human DDB1 (deltaBPB) and rat STAT2 CCD | 分子名称: | B27a, DNA damage-binding protein 1, Signal transducer and activator of transcription, ... | 著者 | Lauer, S, Spahn, C.M.T, Schwefel, D. | 登録日 | 2022-04-20 | 公開日 | 2022-11-09 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor. Embo J., 42, 2023
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8WR5
| The Crystal Structure of Mms2 from Biortus | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, Ubiquitin-conjugating enzyme E2 variant 2 | 著者 | Wang, F, Cheng, W, Yuan, Z, Lin, D, Guo, S. | 登録日 | 2023-10-13 | 公開日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Crystal Structure of Mms2 from Biortus. To Be Published
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2YML
| Native L-haloacid dehalogenase from a Rhodobacteraceae family bacterium | 分子名称: | L-HALOACID DEHALOGENASE | 著者 | Novak, H.R, Sayer, C, Isupov, M.N, Paszkiewicz, K, Gotz, D, Spragg, A.M, Littlechild, J.A. | 登録日 | 2012-10-09 | 公開日 | 2013-05-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Marine Rhodobacteraceae L-Haloacid Dehalogenase Contains a Novel His/Glu Dyad that Could Activate the Catalytic Water. FEBS J., 280, 2013
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7ZNN
| Cryo-EM structure of RCMV-E E27 bound to human DDB1 (deltaBPB) and full-length rat STAT2 | 分子名称: | B27a, DNA damage-binding protein 1, Signal transducer and activator of transcription, ... | 著者 | Lauer, S, Spahn, C.M.T, Schwefel, D. | 登録日 | 2022-04-21 | 公開日 | 2022-11-09 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor. Embo J., 42, 2023
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8WRA
| The Crystal Structure of CASP1 from Biortus | 分子名称: | 1,2-ETHANEDIOL, Caspase-1 | 著者 | Wang, F, Cheng, W, Yuan, Z, Lin, D, Guo, S. | 登録日 | 2023-10-13 | 公開日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | The Crystal Structure of CASP1 from Biortus. To Be Published
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2BR7
| Crystal Structure of Acetylcholine-binding Protein (AChBP) from Aplysia californica in complex with HEPES | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SOLUBLE ACETYLCHOLINE RECEPTOR | 著者 | Celie, P.H.N, Kasheverov, I.E, Mordvintsev, D.Y, Hogg, R.C, Van Nierop, P, Van Elk, R, Van Rossum-Fikkert, S.E, Zhmak, M.N, Bertrand, D, Tsetlin, V, Sixma, T.K, Smit, A.B. | 登録日 | 2005-05-03 | 公開日 | 2005-06-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal Structure of Nicotinic Acetylcholine Receptor Homolog Achbp in Complex with an Alpha- Conotoxin Pnia Variant Nat.Struct.Mol.Biol., 12, 2005
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2YMQ
| Chloropropionic acid complex bound L-haloacid dehalogenase from a Rhodobacteraceae family bacterium | 分子名称: | L-HALOACID DEHALOGENASE | 著者 | Novak, H.R, Sayer, C, Isupov, M.N, Paszkiewicz, K, Gotz, D, Spragg, A.M, Littlechild, J.A. | 登録日 | 2012-10-10 | 公開日 | 2013-05-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Marine Rhodobacteraceae L-Haloacid Dehalogenase Contains a Novel His/Glu Dyad that Could Activate the Catalytic Water. FEBS J., 280, 2013
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7K4N
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2BM2
| human beta-II tryptase in complex with 4-(3-Aminomethyl-phenyl)- piperidin-1-yl-(5-phenethyl- pyridin-3-yl)-methanone | 分子名称: | 1-[3-(1-{[5-(2-PHENYLETHYL)PYRIDIN-3-YL]CARBONYL}PIPERIDIN-4-YL)PHENYL]METHANAMINE, HUMAN BETA2 TRYPTASE | 著者 | Maignan, S, Guilloteau, J.-P, Dupuy, A, Levell, J, Astles, P, Eastwood, P, Cairns, J, Houille, O, Aldous, S, Merriman, G, Whiteley, B, Pribish, J, Czekaj, M, Liang, G, Davidson, J, Harrison, T, Morley, A, Watson, S, Fenton, G, Mccarthy, C, Romano, J, Mathew, R, Engers, D, Gardyan, M, Sides, K, Kwong, J, Tsay, J, Rebello, S, Shen, L, Wang, J, Luo, Y, Giardino, O, Lim, H.-K, Smith, K, Pauls, H. | 登録日 | 2005-03-09 | 公開日 | 2005-03-22 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure Based Design of 4-(3-Aminomethylphenyl) Piperidinyl-1-Amides: Novel, Potent, Selective, and Orally Bioavailable Inhibitors of Bii Tryptase Bioorg.Med.Chem., 13, 2005
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3ZKT
| SOLUTION STRUCTURE OF THE SOMATOSTATIN SST3 RECEPTOR ANTAGONIST TAU- CONOTOXIN CnVA | 分子名称: | TAU-CNVA | 著者 | Petrel, C, Hocking, H.G, Reynaud, M, Favreau, P, Paolini-Bertrand, M, Peigneur, S, Upert, G, Tytgat, J, Gilles, N, Hartley, O, Boelens, R, Stocklin, R, Servent, D. | 登録日 | 2013-01-24 | 公開日 | 2013-04-24 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Identification, Structural and Pharmacological Characterization of Tau-Cnva, a Conopeptide that Selectively Interacts with Somatostatin Sst3 Receptor. Biochem.Pharmacol, 85, 2013
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7ZPI
| Mammalian Dicer in the "dicing state" with pre-miR-15a substrate | 分子名称: | 59-nt precursor of miR-15a, Endoribonuclease Dicer | 著者 | Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J. | 登録日 | 2022-04-27 | 公開日 | 2022-11-16 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (5.91 Å) | 主引用文献 | Structural and functional basis of mammalian microRNA biogenesis by Dicer. Mol.Cell, 82, 2022
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2YNH
| HIV-1 Reverse Transcriptase in complex with inhibitor GSK500 | 分子名称: | 4-chloranyl-N-[[4-chloranyl-3-(3-chloranyl-5-cyano-phenoxy)-2-fluoranyl-phenyl]methyl]-2-(hydroxymethyl)-1H-imidazole-5-carboxamide, D(-)-TARTARIC ACID, P51 RT, ... | 著者 | Chong, P, Sebahar, P, Youngman, M, Garrido, D, Zhang, H, Stewart, E.L, Nolte, R.T, Wang, L, Ferris, R.G, Edelstein, M, Weaver, K, Mathis, A, Peat, A. | 登録日 | 2012-10-14 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Rational Design of Potent Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase. J.Med.Chem., 55, 2012
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2YPV
| Crystal structure of the Meningococcal vaccine antigen factor H binding protein in complex with a bactericidal antibody | 分子名称: | 1,2-ETHANEDIOL, FAB 12C1, LIPOPROTEIN | 著者 | Malito, E, Veggi, D, Bottomley, M.J. | 登録日 | 2012-11-01 | 公開日 | 2013-02-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Defining a Protective Epitope on Factor H Binding Protein, a Key Meningococcal Virulence Factor and Vaccine Antigen. Proc.Natl.Acad.Sci.USA, 110, 2013
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2BR8
| Crystal Structure of Acetylcholine-binding Protein (AChBP) from Aplysia californica in complex with an alpha-conotoxin PnIA variant | 分子名称: | ALPHA-CONOTOXIN PNIA, SOLUBLE ACETYLCHOLINE RECEPTOR, SULFATE ION | 著者 | Celie, P.H.N, Kasheverov, I.E, Mordvintsev, D.Y, Hogg, R.C, van Nierop, P, van Elk, R, van Rossum-Fikkert, S.E, Zhmak, M.N, Bertrand, D, Tsetlin, V, Sixma, T.K, Smit, A.B. | 登録日 | 2005-05-03 | 公開日 | 2005-06-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structure of Nicotinic Acetylcholine Receptor Homolog Achbp in Complex with an Alpha-Conotoxin Pnia Variant Nat.Struct.Mol.Biol., 12, 2005
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2YOB
| High resolution AGXT_M structure | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Fabelo-Rosa, I, Mesa-Torres, N, Riverol, D, Yunta, C, Albert, A, Salido, E, Pey, A.L. | 登録日 | 2012-10-22 | 公開日 | 2013-10-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Role of Protein Denaturation Energetics and Molecular Chaperones in the Aggregation and Mistargeting of Mutants Causing Primary Hyperoxaluria Type I Plos One, 8, 2013
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8WFE
| The Crystal Structure of PPARg from Biortus. | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Peroxisome proliferator-activated receptor gamma | 著者 | Wang, F, Cheng, W, Lv, Z, Guo, S, Lin, D. | 登録日 | 2023-09-19 | 公開日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Crystal Structure of PPARg from Biortus. To Be Published
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7ZHL
| Salmonella enterica Rhs1 C-terminal toxin TreTu | 分子名称: | RHS repeat protein, ZINC ION | 著者 | Jurenas, D, Rey, M, Chamot-Rooke, J, Terradot, L, Cascales, E. | 登録日 | 2022-04-06 | 公開日 | 2022-11-23 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Salmonella antibacterial Rhs polymorphic toxin inhibits translation through ADP-ribosylation of EF-Tu P-loop. Nucleic Acids Res., 50, 2022
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