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7X6Q
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BU of 7x6q by Molmil
cryo-EM structure of human TRiC-ATP-closed state
分子名称: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
著者Cong, Y, Liu, C.X.
登録日2022-03-08
公開日2023-06-07
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7X3U
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BU of 7x3u by Molmil
cryo-EM structure of human TRiC-ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ...
著者Cong, Y, Liu, C.X.
登録日2022-03-01
公開日2023-06-07
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7X7Y
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BU of 7x7y by Molmil
Cryo-EM structure of Human TRiC-ATP-open state
分子名称: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
著者Cong, Y, Liu, C.X.
登録日2022-03-10
公開日2023-06-07
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
2O53
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Crystal structure of apo-Aspartoacylase from human brain
分子名称: Aspartoacylase, PHOSPHATE ION, ZINC ION
著者Le Coq, J, Pavlovsky, A, Sanishvili, R, Viola, R.E.
登録日2006-12-05
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Examination of the Mechanism of Human Brain Aspartoacylase through the Binding of an Intermediate Analogue.
Biochemistry, 47, 2008
2P50
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BU of 2p50 by Molmil
Crystal structure of N-acetyl-D-Glucosamine-6-Phosphate deacetylase liganded with Zn
分子名称: N-acetylglucosamine-6-phosphate deacetylase, ZINC ION
著者Fedorov, A.A, Fedorov, E.V, Hall, R.S, Raushel, F.M, Almo, S.C.
登録日2007-03-14
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Diversity within the Mononuclear and Binuclear Active Sites of N-Acetyl-d-glucosamine-6-phosphate Deacetylase.
Biochemistry, 46, 2007
7Y7M
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BU of 7y7m by Molmil
The structure of coxsackievirus A16 mature virion in complex with Fab 8C4
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Cong, Y, Liu, C.X.
登録日2022-06-22
公開日2022-08-24
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Molecular mechanism of antibody neutralization of coxsackievirus A16.
Nat Commun, 13, 2022
2O4H
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BU of 2o4h by Molmil
Human brain aspartoacylase complex with intermediate analog (N-phosphonomethyl-L-aspartate)
分子名称: Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION
著者Le Coq, J, Pavlovsky, A, Sanishvili, R, Viola, R.E.
登録日2006-12-04
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Examination of the Mechanism of Human Brain Aspartoacylase through the Binding of an Intermediate Analogue.
Biochemistry, 47, 2008
2P39
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BU of 2p39 by Molmil
Crystal structure of human FGF23
分子名称: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, Fibroblast growth factor 23
著者Mohammadi, M.
登録日2007-03-08
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Mol.Cell.Biol., 27, 2007
2PWL
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BU of 2pwl by Molmil
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic N549H Mutation Responsible for Crouzon Syndrome.
分子名称: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION
著者Chen, H, Mohammadi, M.
登録日2007-05-11
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PVF
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BU of 2pvf by Molmil
Crystal Structure of Tyrosine Phosphorylated Activated FGF Receptor 2 (FGFR2) Kinase Domain in Complex with ATP Analog and Substrate Peptide
分子名称: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
著者Chen, H, Mohammadi, M.
登録日2007-05-09
公開日2007-09-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2P23
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BU of 2p23 by Molmil
Crystal structure of human FGF19
分子名称: Fibroblast growth factor 19
著者Mohammadi, M.
登録日2007-03-06
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Mol.Cell.Biol., 27, 2007
2P53
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BU of 2p53 by Molmil
Crystal structure of N-acetyl-D-glucosamine-6-phosphate deacetylase D273N mutant complexed with N-acetyl phosphonamidate-d-glucosamine-6-phosphate
分子名称: 2-deoxy-2-{[(S)-hydroxy(methyl)phosphoryl]amino}-6-O-phosphono-alpha-D-glucopyranose, N-acetylglucosamine-6-phosphate deacetylase, ZINC ION
著者Fedorov, A.A, Fedorov, E.V, Hall, R.S, Raushel, F.M, Almo, S.C.
登録日2007-03-14
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Diversity within the Mononuclear and Binuclear Active Sites of N-Acetyl-d-glucosamine-6-phosphate Deacetylase.
Biochemistry, 46, 2007
2PZ5
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BU of 2pz5 by Molmil
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic N549T Mutation Responsible for Pfeiffer Syndrome
分子名称: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Chen, H, Mohammadi, M.
登録日2007-05-17
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
7CUN
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BU of 7cun by Molmil
The structure of human Integrator-PP2A complex
分子名称: Integrator complex subunit 1, Integrator complex subunit 11, Integrator complex subunit 2, ...
著者Zheng, H, Qi, Y, Liu, W, Li, J, Wang, J, Xu, Y.
登録日2020-08-23
公開日2020-11-25
最終更新日2020-12-09
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase.
Science, 370, 2020
2PSQ
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BU of 2psq by Molmil
Crystal Structure of Unphosphorylated Unactivated Wild Type FGF Receptor 2 (FGFR2) Kinase Domain
分子名称: Fibroblast growth factor receptor 2, SULFATE ION
著者Chen, H, Mohammadi, M.
登録日2007-05-07
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PVY
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BU of 2pvy by Molmil
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K659N Mutation Responsible for an Unclassified Craniosynostosis Syndrome.
分子名称: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION
著者Chen, H, Mohammadi, M.
登録日2007-05-10
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PZR
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BU of 2pzr by Molmil
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K641R Mutation Responsible for Pfeiffer Syndrome
分子名称: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION
著者Chen, H, Mohammadi, M.
登録日2007-05-18
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PY3
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BU of 2py3 by Molmil
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic E565G Mutation Responsible for Pfeiffer Syndrome
分子名称: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Chen, H, Mohammadi, M.
登録日2007-05-15
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PZP
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BU of 2pzp by Molmil
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K526E Mutation Responsible for Crouzon Syndrome
分子名称: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Chen, H, Mohammadi, M.
登録日2007-05-18
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
4TQL
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BU of 4tql by Molmil
Computationally designed three helix bundle
分子名称: Three helix bundle
著者Nannenga, B.L, Oberdorfer, G, DiMaio, F, Baker, D, Gonen, T.
登録日2014-06-11
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献High thermodynamic stability of parametrically designed helical bundles.
Science, 346, 2014
2Q0B
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BU of 2q0b by Molmil
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic E565A Mutation Responsible for Pfeiffer Syndrome
分子名称: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION
著者Chen, H, Mohammadi, M.
登録日2007-05-21
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2QS8
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Crystal structure of a Xaa-Pro dipeptidase with bound methionine in the active site
分子名称: MAGNESIUM ION, METHIONINE, Xaa-Pro Dipeptidase
著者Kumaran, D, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-07-30
公開日2007-08-21
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Functional annotation of two new carboxypeptidases from the amidohydrolase superfamily of enzymes.
Biochemistry, 48, 2009
7VPP
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BU of 7vpp by Molmil
Structures of a deltacoronavirus spike protein bound to porcine and human receptors indicate the risk of virus adaptation to humans
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ji, W, Xu, Y, Zhang, S.
登録日2021-10-17
公開日2022-03-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Structures of a deltacoronavirus spike protein bound to porcine and human receptors.
Nat Commun, 13, 2022
7VPQ
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Structures of a deltacoronavirus spike protein bound to porcine and human receptors indicate the risk of virus adaptation to humans
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ji, W, Xu, Y, Zhang, S.
登録日2021-10-17
公開日2022-03-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of a deltacoronavirus spike protein bound to porcine and human receptors.
Nat Commun, 13, 2022
2I7K
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Solution Structure of the Bromodomain of Human BRD7 Protein
分子名称: Bromodomain-containing protein 7
著者Sun, H, Liu, J, Zhang, J, Huang, H, Wu, J, Shi, Y.
登録日2006-08-31
公開日2007-07-10
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of BRD7 bromodomain and its interaction with acetylated peptides from histone H3 and H4
Biochem.Biophys.Res.Commun., 358, 2007

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