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6J5U
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Ligand-triggered allosteric ADP release primes a plant NLR complex
分子名称: Disease resistance RPP13-like protein 4, Probable serine/threonine-protein kinase PBL2, Protein kinase superfamily protein, ...
著者Wang, J.Z, Wang, J, Meijuan, H, Wang, H.W, Zhou, J.M, Chai, J.J.
登録日2019-01-12
公開日2019-04-03
最終更新日2023-04-05
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Ligand-triggered allosteric ADP release primes a plant NLR complex.
Science, 364, 2019
8G8F
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Human IMPDH2 mutant - L245P, treated with ATP, IMP, and NAD+; extended filament segment reconstruction
分子名称: ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, ...
著者O'Neill, A.G, Kollman, J.M.
登録日2023-02-17
公開日2023-04-19
最終更新日2023-08-09
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J.Biol.Chem., 299, 2023
6J5V
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BU of 6j5v by Molmil
Ligand-triggered allosteric ADP release primes a plant NLR complex
分子名称: Disease resistance RPP13-like protein 4, Probable serine/threonine-protein kinase PBL2, Protein kinase superfamily protein, ...
著者Wang, J.Z, Wang, J, Hu, M.J, Wang, H.W, Zhou, J.M, Chai, J.J.
登録日2019-01-12
公開日2019-04-03
最終更新日2023-04-05
実験手法ELECTRON MICROSCOPY (4.25 Å)
主引用文献Ligand-triggered allosteric ADP release primes a plant NLR complex.
Science, 364, 2019
8JIX
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BU of 8jix by Molmil
Crystal structure of the Bagaza virus helicase and structure-based discovery of a novel inhibitor
分子名称: Genome polyprotein
著者Zhao, R, Shu, W, Cao, J.M, Zhou, X, Wang, D.P.
登録日2023-05-29
公開日2024-03-06
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Crystal structure of the Bagaza virus helicase and structure-based discovery of a novel inhibitor
To Be Published
8B2C
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BU of 8b2c by Molmil
Crystal structure of type I dehydroquinase from Salmonella typhi inhibited by an epoxide derivative
分子名称: (1~{S},2~{R},4~{R},5~{S},6~{S})-2,4,5-trihydroxy-7-oxabicyclo[4.1.0]heptane-2-carboxylic acid, 3-dehydroquinate dehydratase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Otero, J.M, Rodriguez, A, Maneiro, M, Lence, E, Thompson, P, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J.
登録日2022-09-13
公開日2023-02-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Quinate-based ligands for irreversible inactivation of the bacterial virulence factor DHQ1 enzyme-A molecular insight.
Front Mol Biosci, 10, 2023
8B2A
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Crystal structure of type I dehydroquinase from Salmonella typhi inhibited by an epoxide derivative
分子名称: (4R,5R)-3-amino-4,5-dihydroxy-cyclohexene-1-carboxylic acid, 3-dehydroquinate dehydratase, CHLORIDE ION, ...
著者Otero, J.M, Rodriguez, A, Maneiro, M, Lence, E, Thompson, P, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J.
登録日2022-09-13
公開日2023-02-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Quinate-based ligands for irreversible inactivation of the bacterial virulence factor DHQ1 enzyme-A molecular insight.
Front Mol Biosci, 10, 2023
8B2B
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Crystal structure of type I dehydroquinase from Salmonella typhi inhibited by an epoxide derivative
分子名称: (4R,5R)-3-amino-4,5-dihydroxy-cyclohexene-1-carboxylic acid, 3-dehydroquinate dehydratase, SODIUM ION
著者Otero, J.M, Rodriguez, A, Maneiro, M, Lence, E, Thompson, P, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J.
登録日2022-09-13
公開日2023-02-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Quinate-based ligands for irreversible inactivation of the bacterial virulence factor DHQ1 enzyme-A molecular insight.
Front Mol Biosci, 10, 2023
6HG4
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Crystal Structure of the human IL-17RC ECD in complex with human IL-17F
分子名称: Interleukin-17 receptor C, Interleukin-17F
著者Rondeau, J.M, Goepfert, A.
登録日2018-08-22
公開日2020-03-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling.
Immunity, 52, 2020
6HGA
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Crystal Structure of the human IL-17RC D2-D3-D4 domains in complex with an anti-APP tag Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor C, anti-APP-tag Fab heavy-chain, ...
著者Rondeau, J.M, Goepfert, A.
登録日2018-08-23
公開日2020-03-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling.
Immunity, 52, 2020
6HA4
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BU of 6ha4 by Molmil
Crystal structure of PAF - p-sulfonatocalix[4]arene complex
分子名称: 25,26,27,28-tetrahydroxypentacyclo[19.3.1.1~3,7~.1~9,13~.1~15,19~]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-5,11,17,23-tetrasulfonic acid, GLYCEROL, Pc24g00380 protein
著者Alex, J.M, Rennie, M, Engilberge, S, Batta, G, Crowley, P.B.
登録日2018-08-07
公開日2019-02-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Calixarene-mediated assembly of a small antifungal protein.
Iucrj, 6, 2019
8JJG
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Crystal structure of QW-hNTAQ1 C28S
分子名称: Protein N-terminal glutamine amidohydrolase
著者Kang, J.M, Han, B.W.
登録日2023-05-30
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural study for substrate recognition of human N-terminal glutamine amidohydrolase 1 in the arginine N-degron pathway.
Protein Sci., 33, 2024
8JJI
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Crystal structure of QR-hNTAQ1 C28S
分子名称: Protein N-terminal glutamine amidohydrolase
著者Kang, J.M, Han, B.W.
登録日2023-05-30
公開日2024-06-26
実験手法X-RAY DIFFRACTION (2.206 Å)
主引用文献Structural study for substrate recognition of human N-terminal glutamine amidohydrolase 1 in the arginine N-degron pathway.
Protein Sci., 33, 2024
8JK0
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Crystal structure of QL-hNTAQ1 C28S
分子名称: Protein N-terminal glutamine amidohydrolase
著者Kang, J.M, Han, B.W.
登録日2023-05-31
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural study for substrate recognition of human N-terminal glutamine amidohydrolase 1 in the arginine N-degron pathway.
Protein Sci., 33, 2024
8JJH
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Crystal structure of QH-hNTAQ1 C28S
分子名称: Protein N-terminal glutamine amidohydrolase
著者Kang, J.M, Han, B.W.
登録日2023-05-30
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Structural study for substrate recognition of human N-terminal glutamine amidohydrolase 1 in the arginine N-degron pathway.
Protein Sci., 33, 2024
8JJX
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Crystal structure of QS-hNTAQ1 C28S
分子名称: Protein N-terminal glutamine amidohydrolase
著者Kang, J.M, Han, B.W.
登録日2023-05-31
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural study for substrate recognition of human N-terminal glutamine amidohydrolase 1 in the arginine N-degron pathway.
Protein Sci., 33, 2024
8JJF
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Crystal structure of QE-hNTAQ1 C28S
分子名称: Protein N-terminal glutamine amidohydrolase
著者Kang, J.M, Han, B.W.
登録日2023-05-30
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Structural study for substrate recognition of human N-terminal glutamine amidohydrolase 1 in the arginine N-degron pathway.
Protein Sci., 33, 2024
8JJZ
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Crystal structure of QQ-hNTAQ1 C28S
分子名称: Protein N-terminal glutamine amidohydrolase
著者Kang, J.M, Han, B.W.
登録日2023-05-31
公開日2024-06-26
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structural study for substrate recognition of human N-terminal glutamine amidohydrolase 1 in the arginine N-degron pathway.
Protein Sci., 33, 2024
6HK6
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BU of 6hk6 by Molmil
Human RIOK2 bound to inhibitor
分子名称: 1,2-ETHANEDIOL, 2-naphthalen-2-yl-~{N}-pyridin-2-yl-ethanamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Wang, J, Krojer, T, Bountra, C, Edwards, A.M, Arrowsmith, C, Knapp, S, Elkins, J.M.
登録日2018-09-05
公開日2018-10-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structure of human RIOK2 bound to a specific inhibitor.
Open Biology, 9, 2019
8JJU
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BU of 8jju by Molmil
Crystal structure of QD-hNTAQ1 C28S
分子名称: Protein N-terminal glutamine amidohydrolase
著者Kang, J.M, Han, B.W.
登録日2023-05-31
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Structural study for substrate recognition of human N-terminal glutamine amidohydrolase 1 in the arginine N-degron pathway.
Protein Sci., 33, 2024
8JK1
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BU of 8jk1 by Molmil
Crystal structure of QA-hNTAQ1 C28S
分子名称: Protein N-terminal glutamine amidohydrolase
著者Kang, J.M, Han, B.W.
登録日2023-05-31
公開日2024-06-26
実験手法X-RAY DIFFRACTION (2.067 Å)
主引用文献Structural study for substrate recognition of human N-terminal glutamine amidohydrolase 1 in the arginine N-degron pathway.
Protein Sci., 33, 2024
6H9G
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BU of 6h9g by Molmil
Influenza A nucleoprotein docked into 3D helical structure of the wild type ribonucleoprotein complex obtained using cryoEM. Conformation 1.
分子名称: Nucleoprotein, Polypeptide loop
著者Coloma, R, Arranz, R, de la Rosa-Trevin, J.M, Sorzano, C.O.S, Munier, S, Carlero, D, Naffakh, N, Ortin, J, Martin-Benito, J.
登録日2018-08-03
公開日2020-02-12
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (11 Å)
主引用文献Structural insights into influenza A virus ribonucleoproteins reveal a processive helical track as transcription mechanism.
Nat Microbiol, 5, 2020
8OH9
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BU of 8oh9 by Molmil
Cryo-EM structure of the electron bifurcating transhydrogenase StnABC complex from Sporomusa Ovata (state 1)
分子名称: FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, Formate dehydrogenase-O, ...
著者Kumar, A, Kremp, F, Mueller, V, Schuller, J.M.
登録日2023-03-20
公開日2023-09-13
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Molecular architecture and electron transfer pathway of the Stn family transhydrogenase.
Nat Commun, 14, 2023
8OH5
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Cryo-EM structure of the electron bifurcating transhydrogenase StnABC complex from Sporomusa Ovata (state 2)
分子名称: FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Kumar, A, Kremp, F, Mueller, V, Schuller, J.M.
登録日2023-03-20
公開日2023-09-13
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular architecture and electron transfer pathway of the Stn family transhydrogenase.
Nat Commun, 14, 2023
8OK0
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Crystal structure of human NQO1 in complex with the inhibitor PMSF
分子名称: ACETYL GROUP, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Martin-Garcia, J.M, Grieco, A, Ruiz-Fresneda, M.A.
登録日2023-03-26
公開日2023-11-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural dynamics at the active site of the cancer-associated flavoenzyme NQO1 probed by chemical modification with PMSF.
Febs Lett., 597, 2023
6HG7
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BU of 6hg7 by Molmil
Crystal structure of a collagen II fragment containing the binding site of PEDF and COMP, (POG)4-LKG HRG FTG LQG-POG(4)
分子名称: Collagen alpha-1(II) chain, SULFATE ION
著者Gebauer, J.M, Koehler, A, Dietmar, H, Gompert, M, Neundorf, I, Zaucke, F, Koch, M, Baumann, U.
登録日2018-08-22
公開日2018-12-05
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献COMP and TSP-4 interact specifically with the novel GXKGHR motif only found in fibrillar collagens.
Sci Rep, 8, 2018

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