8B2C
Crystal structure of type I dehydroquinase from Salmonella typhi inhibited by an epoxide derivative
This is a non-PDB format compatible entry.
Summary for 8B2C
Entry DOI | 10.2210/pdb8b2c/pdb |
Descriptor | 3-dehydroquinate dehydratase, (1~{S},2~{R},4~{R},5~{S},6~{S})-2,4,5-trihydroxy-7-oxabicyclo[4.1.0]heptane-2-carboxylic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (5 entities in total) |
Functional Keywords | chorismate biosynthetic process, 3-dehydroquinase, lyase |
Biological source | Salmonella enterica subsp. enterica serovar Typhi |
Total number of polymer chains | 1 |
Total formula weight | 28301.57 |
Authors | Otero, J.M.,Rodriguez, A.,Maneiro, M.,Lence, E.,Thompson, P.,Hawkins, A.R.,Gonzalez-Bello, C.,van Raaij, M.J. (deposition date: 2022-09-13, release date: 2023-02-15, Last modification date: 2024-02-07) |
Primary citation | Rodriguez, A.,Maneiro, M.,Lence, E.,Otero, J.M.,van Raaij, M.J.,Thompson, P.,Hawkins, A.R.,Gonzalez-Bello, C. Quinate-based ligands for irreversible inactivation of the bacterial virulence factor DHQ1 enzyme-A molecular insight. Front Mol Biosci, 10:1111598-1111598, 2023 Cited by PubMed: 36762206DOI: 10.3389/fmolb.2023.1111598 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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