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7Y0T
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BU of 7y0t by Molmil
Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanyl-L-phenylalanine
分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, I7X-PHE-PHE, PROTOPORPHYRIN IX CONTAINING FE
著者Jiang, Y, Dong, S, Feng, Y, Cong, Z.
登録日2022-06-06
公開日2023-06-14
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Anchoring a Structurally Editable Proximal Cofactor-like Module to Construct an Artificial Dual-center Peroxygenase.
Angew.Chem.Int.Ed.Engl., 62, 2023
1OCD
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BU of 1ocd by Molmil
CYTOCHROME C (OXIDIZED) FROM EQUUS CABALLUS, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: CYTOCHROME C, HEME C
著者Qi, P.X, Beckman, R.A, Wand, A.J.
登録日1996-07-03
公開日1997-06-16
最終更新日2018-03-14
実験手法SOLUTION NMR
主引用文献Solution structure of horse heart ferricytochrome c and detection of redox-related structural changes by high-resolution 1H NMR.
Biochemistry, 35, 1996
8R3Z
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BU of 8r3z by Molmil
Cryo-EM structure of the Asgard archaeal Argonaute HrAgo1 bound to a guide RNA
分子名称: HrAgo1, MAGNESIUM ION, RNA (5'-R(P*UP*GP*AP*GP*GP*U*(MG))-3')
著者Finocchio, G, Swarts, D, Jinek, M.
登録日2023-11-10
公開日2024-06-19
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献RNA-guided RNA silencing by an Asgard archaeal Argonaute.
Nat Commun, 15, 2024
4PS4
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BU of 4ps4 by Molmil
Crystal structure of the complex between IL-13 and M1295 FAB
分子名称: Interleukin-13, M1295 HEAVY CHAIN, M1295 LIGHT CHAIN
著者Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
登録日2014-03-06
公開日2014-03-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Human Framework Adaptation of a Mouse Anti-Human Il-13 Antibody.
J.Mol.Biol., 398, 2010
3LFM
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BU of 3lfm by Molmil
Crystal structure of the fat mass and obesity associated (FTO) protein reveals basis for its substrate specificity
分子名称: 3-methylthymidine, FE (II) ION, N-OXALYLGLYCINE, ...
著者Chai, J, Han, Z.
登録日2010-01-18
公開日2010-04-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the FTO protein reveals basis for its substrate specificity
Nature, 464, 2010
3NAC
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BU of 3nac by Molmil
Crystal structure of Fab15 Mut7
分子名称: ACETATE ION, Fab15 Mut7 heavy chain, Fab15 Mut7 light chain, ...
著者Luo, J.
登録日2010-06-01
公開日2010-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Co-evolution of antibody stability and Vk CDR-L3 canonical structure
To be Published
3NA9
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BU of 3na9 by Molmil
Crystal structure of Fab15
分子名称: ACETATE ION, Fab15 heavy chain, Fab15 light chain, ...
著者Luo, J.
登録日2010-06-01
公開日2010-08-18
最終更新日2021-03-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Co-evolution of antibody stability and Vk CDR-L3 canonical structure
To be Published
5CCU
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BU of 5ccu by Molmil
Crystal structure of endoglycoceramidase I from Rhodococ-cus equi
分子名称: 1,2-ETHANEDIOL, Putative secreted endoglycosylceramidase, SODIUM ION
著者Chen, L.
登録日2015-07-02
公開日2015-09-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structural Insights into the Broad Substrate Specificity of a Novel Endoglycoceramidase I Belonging to a New Subfamily of GH5 Glycosidases
J. Biol. Chem., 292, 2017
3NAB
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BU of 3nab by Molmil
Crystal Structure of fab15 Mut6
分子名称: ACETATE ION, Fab15 Mut6 heavy chain, Fab15 Mut6 light chain, ...
著者Luo, J.
登録日2010-06-01
公開日2010-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Co-evolution of antibody stability and Vk CDR-L3 canonical structure
To be Published
5ZOI
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BU of 5zoi by Molmil
Crystal Structure of alpha1,3-Fucosyltransferase
分子名称: Alpha-(1,3)-fucosyltransferase FucT, [[(2S,3R,4S,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4S,5R,6R)-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl] hydrogen phosphate
著者Tan, Y, Yang, G.
登録日2018-04-13
公開日2019-06-26
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Directed evolution of an alpha 1,3-fucosyltransferase using a single-cell ultrahigh-throughput screening method.
Sci Adv, 5, 2019
5EWI
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BU of 5ewi by Molmil
Crystal Structure of the Human Fab VRC38.01, an HIV-1 V1V2-Directed Neutralizing Antibody Isolated from Donor N90
分子名称: VRC38.01 Heavy Chain, VRC38.01 Light Chain
著者Gorman, J, Kwong, P.D.
登録日2015-11-20
公開日2016-11-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5996 Å)
主引用文献Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop.
Immunity, 46, 2017
5J14
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BU of 5j14 by Molmil
Crystal structure of endoglycoceramidase I from Rhodococ-cus equi in complex with GM3
分子名称: N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)STEARAMIDE, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Putative secreted endoglycosylceramidase, ...
著者Chen, L.
登録日2016-03-28
公開日2016-04-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.915 Å)
主引用文献Structural Insights into the Broad Substrate Specificity of a Novel Endoglycoceramidase I Belonging to a New Subfamily of GH5 Glycosidases
J. Biol. Chem., 292, 2017
6JBQ
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BU of 6jbq by Molmil
CryoEM structure of Escherichia coli sigmaE transcription initiation complex containing 5nt of RNA
分子名称: DNA (48-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Fang, C.L, Zhang, Y.
登録日2019-01-26
公開日2019-05-29
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
6JCX
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BU of 6jcx by Molmil
Mycobacterium tuberculosis transcription initiation complex with ECF sigma factor sigma H and 6nt RNA
分子名称: DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Li, L, Zhang, Y.
登録日2019-01-30
公開日2019-05-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.903 Å)
主引用文献Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
5J7Z
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BU of 5j7z by Molmil
Crystal structure of endoglycoceramidase I from Rhodococ-cus equi in complex with GM1
分子名称: N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)STEARAMIDE, Putative secreted endoglycosylceramidase, SODIUM ION, ...
著者Chen, L.
登録日2016-04-07
公開日2016-04-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural Insights into the Broad Substrate Specificity of a Novel Endoglycoceramidase I Belonging to a New Subfamily of GH5 Glycosidases.
J. Biol. Chem., 292, 2017
6JCY
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BU of 6jcy by Molmil
Mycobacterium tuberculosis RNA polymerase transcription initiation open complex with a chimeric ECF sigma factor sigH/E
分子名称: DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Li, L, Zhang, Y.
登録日2019-01-30
公開日2019-05-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.106 Å)
主引用文献Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
6J9E
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BU of 6j9e by Molmil
Cryo-EM structure of Xanthomonos oryzae transcription elongation complex with NusA and the bacteriophage protein P7
分子名称: 45L, DNA (29-MER), DNA-directed RNA polymerase subunit alpha, ...
著者You, L.L, Zhang, Y.
登録日2019-01-22
公開日2019-07-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Structural basis for transcription antitermination at bacterial intrinsic terminator.
Nat Commun, 10, 2019
5EKU
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BU of 5eku by Molmil
Crystal Structure of Trypanosoma Brucei Protein Arginine Methyltransferase PRMT7 in complex with S-Adenosyl-L-homocysteine
分子名称: Arginine N-methyltransferase, putative, S-ADENOSYL-L-HOMOCYSTEINE
著者Debler, E.W, Stavropoulos, P.
登録日2015-11-04
公開日2016-05-18
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献A glutamate/aspartate switch controls product specificity in a protein arginine methyltransferase.
Proc.Natl.Acad.Sci.USA, 113, 2016
6J9F
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BU of 6j9f by Molmil
Cryo-EM structure of Xanthomonos oryzae transcription elongation complex with the bacteriophage protein P7
分子名称: 45L, DNA (29-MER), DNA-directed RNA polymerase subunit alpha, ...
著者You, L.L, Zhang, Y.
登録日2019-01-22
公開日2019-07-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.95 Å)
主引用文献Structural basis for transcription antitermination at bacterial intrinsic terminator.
Nat Commun, 10, 2019
6KJ6
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BU of 6kj6 by Molmil
cryo-EM structure of Escherichia coli Crl transcription activation complex
分子名称: DNA (51-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Xu, J, Zhang, Y.
登録日2019-07-21
公開日2020-01-01
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Crl activates transcription by stabilizing active conformation of the master stress transcription initiation factor.
Elife, 8, 2019
4G34
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BU of 4g34 by Molmil
Crystal Structure of GSK6924 Bound to PERK (R587-R1092, delete A660-T867) at 2.70 A Resolution
分子名称: 1-[5-(4-aminothieno[3,2-c]pyridin-3-yl)-2,3-dihydro-1H-indol-1-yl]-2-phenylethanone, Eukaryotic translation initiation factor 2-alpha kinase 3
著者Gampe, R.T, Axten, J.M.
登録日2012-07-13
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK).
J.Med.Chem., 55, 2012
4G31
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BU of 4g31 by Molmil
Crystal Structure of GSK6414 Bound to PERK (R587-R1092, delete A660-T867) at 2.28 A Resolution
分子名称: 1-[5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone, Eukaryotic translation initiation factor 2-alpha kinase 3, GLYCEROL
著者Gampe, R.T, Axten, J.M.
登録日2012-07-13
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK).
J.Med.Chem., 55, 2012
4FWI
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BU of 4fwi by Molmil
Crystal structure of the nucleotide-binding domain of a dipeptide ABC transporter
分子名称: ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Li, X, Ge, J, Yang, M, Wang, N.
登録日2012-07-01
公開日2013-01-30
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.892 Å)
主引用文献Structure of the nucleotide-binding domain of a dipeptide ABC transporter reveals a novel iron-sulfur cluster-binding domain
Acta Crystallogr.,Sect.D, 69, 2013
2ZW0
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BU of 2zw0 by Molmil
Crystal structure of a Streptococcal protein G B1 mutant
分子名称: Protein LG, SULFATE ION
著者Watanabe, H, Matsumaru, H, Odahara, T, Suto, K, Honda, S.
登録日2008-11-26
公開日2009-03-03
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Optimizing pH response of affinity between protein G and IgG Fc: how electrostatic modulations affect protein-protein interactions.
J.Biol.Chem., 284, 2009
2ZW1
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BU of 2zw1 by Molmil
Crystal structure of a Streptococcal protein G B1 mutant
分子名称: Protein LG
著者Watanabe, H, Matsumaru, H, Odahara, T, Suto, K, Honda, S.
登録日2008-11-26
公開日2009-03-03
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Optimizing pH response of affinity between protein G and IgG Fc: how electrostatic modulations affect protein-protein interactions.
J.Biol.Chem., 284, 2009

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