4CL3
 
 | | 1.70 A resolution structure of the malate dehydrogenase from Chloroflexus aurantiacus | | 分子名称: | ACETATE ION, CADMIUM ION, CHLORIDE ION, ... | | 著者 | Talon, R, Madern, D, Girard, E. | | 登録日 | 2014-01-11 | | 公開日 | 2014-02-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.699 Å) | | 主引用文献 | An Experimental Point of View on Hydration/Solvation in Halophilic Proteins.
Front.Microbiol., 5, 2014
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5T31
 | | Exploiting an Asp-Glu switch in Glycogen Synthase Kinase 3 to design paralog selective inhibitors for use in acute myeloid leukemia | | 分子名称: | (4~{S})-4-ethyl-7,7-dimethyl-4-phenyl-2,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one, Glycogen synthase kinase-3 beta | | 著者 | Stein, A.J, Holson, E.B, Wagner, F.F, Cambell, A.J. | | 登録日 | 2016-08-24 | | 公開日 | 2018-02-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia.
Sci Transl Med, 10, 2018
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4M6L
 | | Crystal structure of human dihydrofolate reductase (DHFR) bound to NADP+ and 5,10-dideazatetrahydrofolic acid | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Dihydrofolate reductase, N-(4-{2-[(6S)-2-amino-4-oxo-1,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin-6-yl]ethyl}benzoyl)-L-glutamic acid, ... | | 著者 | Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A. | | 登録日 | 2013-08-09 | | 公開日 | 2013-09-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Divergent evolution of protein conformational dynamics in dihydrofolate reductase.
Nat.Struct.Mol.Biol., 20, 2013
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4M6J
 | | Crystal structure of human dihydrofolate reductase (DHFR) bound to NADPH | | 分子名称: | Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A. | | 登録日 | 2013-08-09 | | 公開日 | 2013-09-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.201 Å) | | 主引用文献 | Divergent evolution of protein conformational dynamics in dihydrofolate reductase.
Nat.Struct.Mol.Biol., 20, 2013
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5MJD
 | | metNgb under oxygen at 80 bar | | 分子名称: | Neuroglobin, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Prange, T, Colloc'h, N, Carpentier, P. | | 登録日 | 2016-11-30 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Ligand pathways in neuroglobin revealed by low-temperature photodissociation and docking experiments.
Iucrj, 6, 2019
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5MJC
 | | metNeuroglobin under oxygen at 50 bar | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, Neuroglobin, OXYGEN MOLECULE, ... | | 著者 | Prange, T, Colloc'h, N, Carpentier, P, Vallone, B. | | 登録日 | 2016-11-30 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Ligand pathways in neuroglobin revealed by low-temperature photodissociation and docking experiments.
Iucrj, 6, 2019
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3EY6
 | | Crystal structure of the FK506-binding domain of human FKBP38 | | 分子名称: | FK506-binding protein 8 | | 著者 | Parthier, C, Maestre-Martinez, M, Neumann, P, Edlich, F, Fischer, G, Luecke, C, Stubbs, M.T. | | 登録日 | 2008-10-19 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | A charge-sensitive loop in the FKBP38 catalytic domain modulates Bcl-2 binding.
J.Mol.Recognit., 24, 2011
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7K5C
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3GIV
 | | Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance | | 分子名称: | Beta-2-microglobulin, HIV-1 peptide, HLA class I histocompatibility antigen, ... | | 著者 | Stewart-Jones, G, Iversen, A.K.N, Jones, E.Y. | | 登録日 | 2009-03-06 | | 公開日 | 2009-06-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance
Nat.Immunol., 10, 2009
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3UGU
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3UGX
 | | Crystal Structure of Visual Arrestin | | 分子名称: | 1,2-ETHANEDIOL, IMIDAZOLE, PENTANEDIAL, ... | | 著者 | Batra-Safferling, R, Granzin, J. | | 登録日 | 2011-11-03 | | 公開日 | 2012-02-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.649 Å) | | 主引用文献 | Crystal Structure of p44, a Constitutively Active Splice Variant of Visual Arrestin.
J.Mol.Biol., 416, 2012
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8OGK
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7XRC
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2V9U
 | | Rim domain of main porin from Mycobacteria smegmatis | | 分子名称: | MSPA | | 著者 | Grueninger, D, Ziegler, M.O.P, Koetter, J.W.A, Treiber, N, Schulze, M.-S, Schulz, G.E. | | 登録日 | 2007-08-27 | | 公開日 | 2008-01-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Designed Protein-Protein Association.
Science, 319, 2008
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3U7H
 | | Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTTp) | | 分子名称: | Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ... | | 著者 | Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M. | | 登録日 | 2011-10-13 | | 公開日 | 2011-12-14 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3U7E
 | | Crystal structure of mPNKP catalytic fragment (D170A) | | 分子名称: | Bifunctional polynucleotide phosphatase/kinase, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M. | | 登録日 | 2011-10-13 | | 公開日 | 2011-12-14 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3U7F
 | | Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTCp) | | 分子名称: | Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ... | | 著者 | Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M. | | 登録日 | 2011-10-13 | | 公開日 | 2011-12-14 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3U7G
 | | Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp) | | 分子名称: | Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ... | | 著者 | Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M. | | 登録日 | 2011-10-13 | | 公開日 | 2011-12-14 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
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2V65
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2LCA
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2LBT
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2MLI
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2LW3
 | | Solution structure of the soluble domain of MmpS4 from Mycobacterium tuberculosis | | 分子名称: | Putative membrane protein mmpS4 | | 著者 | Xi, Z, Sun, P, Wang, W, Lai, C, Wu, F, Tian, C. | | 登録日 | 2012-07-19 | | 公開日 | 2013-03-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Discovery of a Siderophore Export System Essential for Virulence of Mycobacterium tuberculosis
Plos Pathog., 9, 2013
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