5JY7
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8V9K
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![BU of 8v9k by Molmil](/molmil-images/mine/8v9k) | Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Rv2629 (Balon) (Structure 5) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S2, ... | 著者 | Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. | 登録日 | 2023-12-08 | 公開日 | 2024-02-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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8V9L
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![BU of 8v9l by Molmil](/molmil-images/mine/8v9l) | Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Msmeg1130 (Balon) and MsmegEF-Tu(GDP) (Composite structure 6) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S2, ... | 著者 | Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. | 登録日 | 2023-12-08 | 公開日 | 2024-02-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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8V9J
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![BU of 8v9j by Molmil](/molmil-images/mine/8v9j) | Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Msmeg1130 (Balon) (Structure 4) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S14, ... | 著者 | Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. | 登録日 | 2023-12-08 | 公開日 | 2024-02-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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6J2A
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![BU of 6j2a by Molmil](/molmil-images/mine/6j2a) | The structure of HLA-A*3003/NP44 | 分子名称: | Beta-2-microglobulin, HLA-A*3003, NP44 | 著者 | Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, F.G, Lou, Y.L, Liu, W.J. | 登録日 | 2018-12-31 | 公開日 | 2019-09-25 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides. Front Immunol, 10, 2019
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6J1W
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![BU of 6j1w by Molmil](/molmil-images/mine/6j1w) | The structure of HLA-A*3001/RT313 | 分子名称: | ALA-ILE-PHE-GLN-SER-SER-MET-THR-LYS, Beta-2-microglobulin, HLA-A*3001 | 著者 | Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, G.F, Lou, Y.L, Liu, W.J. | 登録日 | 2018-12-29 | 公開日 | 2019-09-25 | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | 主引用文献 | Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides. Front Immunol, 10, 2019
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6J29
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![BU of 6j29 by Molmil](/molmil-images/mine/6j29) | The structure of HLA-A*3003/MTB | 分子名称: | Beta-2-microglobulin, HLA-A*3003, MTB | 著者 | Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, F.G, Lou, Y.L, Liu, W.J. | 登録日 | 2018-12-31 | 公開日 | 2019-09-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides. Front Immunol, 10, 2019
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8U0U
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![BU of 8u0u by Molmil](/molmil-images/mine/8u0u) | DdmD dimer in complex with ssDNA | 分子名称: | DNA (5'-D(P*TP*TP*AP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Helicase/UvrB N-terminal domain-containing protein | 著者 | Bravo, J.P.K. | 登録日 | 2023-08-29 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Plasmid targeting and destruction by the DdmDE bacterial defence system. Nature, 630, 2024
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8U0W
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![BU of 8u0w by Molmil](/molmil-images/mine/8u0w) | DdmD monomer in complex with ssDNA | 分子名称: | DNA (5'-D(P*TP*TP*AP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Helicase/UvrB N-terminal domain-containing protein | 著者 | Bravo, J.P.K. | 登録日 | 2023-08-29 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | 主引用文献 | Plasmid targeting and destruction by the DdmDE bacterial defence system. Nature, 630, 2024
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8U3K
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![BU of 8u3k by Molmil](/molmil-images/mine/8u3k) | DdmDE handover complex | 分子名称: | DNA (29-MER), DNA (5'-D(P*GP*GP*AP*AP*AP*TP*GP*TP*TP*GP*AP*AP*TP*AP*C)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ... | 著者 | Bravo, J.P.K. | 登録日 | 2023-09-07 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Plasmid targeting and destruction by the DdmDE bacterial defence system. Nature, 630, 2024
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9BQV
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![BU of 9bqv by Molmil](/molmil-images/mine/9bqv) | DdmD dimer apoprotein | 分子名称: | Helicase/UvrB N-terminal domain-containing protein | 著者 | Bravo, J.P.K, Taylor, D.W. | 登録日 | 2024-05-10 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Plasmid targeting and destruction by the DdmDE bacterial defence system. Nature, 630, 2024
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8VTT
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8VTS
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8U0J
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![BU of 8u0j by Molmil](/molmil-images/mine/8u0j) | DdmE in complex with guide and target DNA | 分子名称: | DNA (5'-D(P*AP*CP*TP*TP*AP*AP*AP*GP*TP*CP*TP*AP*AP*CP*CP*TP*AP*TP*AP*GP*GP*AP*T)-3'), DNA (5'-D(P*AP*TP*CP*CP*TP*AP*TP*AP*GP*GP*A)-3'), DNA (5'-D(P*GP*TP*TP*AP*GP*AP*CP*TP*TP*TP*AP*AP*GP*T)-3'), ... | 著者 | Bravo, J.P.K. | 登録日 | 2023-08-29 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Plasmid targeting and destruction by the DdmDE bacterial defence system. Nature, 630, 2024
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2I4T
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![BU of 2i4t by Molmil](/molmil-images/mine/2i4t) | Crystal structure of Purine Nucleoside Phosphorylase from Trichomonas vaginalis with Imm-A | 分子名称: | 3,4-PYRROLIDINEDIOL,2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)-2S,3S,4R,5R, PHOSPHATE ION, Trichomonas vaginalis purine nucleoside phosphorylase | 著者 | Rinaldo-Matthis, A, Schramm, V.L, Almo, S.C. | 登録日 | 2006-08-22 | 公開日 | 2007-06-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues. Biochemistry, 46, 2007
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6JBX
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![BU of 6jbx by Molmil](/molmil-images/mine/6jbx) | Crystal structure of Streptococcus pneumoniae FabT in complex with DNA | 分子名称: | DNA (5'-D(*AP*AP*TP*AP*GP*TP*TP*TP*GP*AP*CP*TP*GP*TP*CP*AP*AP*AP*TP*TP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*AP*AP*TP*TP*TP*GP*AP*CP*AP*GP*TP*CP*AP*AP*AP*CP*TP*AP*TP*T)-3'), Fatty acid biosynthesis transcriptional regulator, ... | 著者 | Zuo, G, Chen, Z.P, Li, Q, Zhou, C.Z. | 登録日 | 2019-01-27 | 公開日 | 2019-07-24 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural insights into repression of the Pneumococcal fatty acid synthesis pathway by repressor FabT and co-repressor acyl-ACP. Febs Lett., 593, 2019
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4QXS
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![BU of 4qxs by Molmil](/molmil-images/mine/4qxs) | Crystal structure of human FPPS in complex with WC01088 | 分子名称: | (2-{2-[(2S)-3-methylbutan-2-yl]-5-phenyl-1H-indol-3-yl}ethane-1,1-diyl)bis(phosphonic acid), Farnesyl pyrophosphate synthase, GLYCEROL, ... | 著者 | Park, J, Zielinski, M, Weiling, C, Tsantrizos, Y.S, Berghuis, A.M. | 登録日 | 2014-07-21 | 公開日 | 2015-02-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase. Bioorg.Med.Chem.Lett., 25, 2015
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5K3E
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![BU of 5k3e by Molmil](/molmil-images/mine/5k3e) | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Glycolate - Cocrystallized | 分子名称: | CHLORIDE ION, Fluoroacetate dehalogenase, GLYCOLIC ACID | 著者 | Mehrabi, P, Kim, T.H, Prosser, S.R, Pai, E.F. | 登録日 | 2016-05-19 | 公開日 | 2017-02-01 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | The role of dimer asymmetry and protomer dynamics in enzyme catalysis. Science, 355, 2017
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5K3A
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![BU of 5k3a by Molmil](/molmil-images/mine/5k3a) | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - His280Asn/Fluoroacetate - Cocrystallized - Both Protomers Reacted with Ligand | 分子名称: | CHLORIDE ION, Fluoroacetate dehalogenase | 著者 | Mehrabi, P, Kim, T.H, Prosser, S.R, Pai, E.F. | 登録日 | 2016-05-19 | 公開日 | 2017-02-01 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.511 Å) | 主引用文献 | The role of dimer asymmetry and protomer dynamics in enzyme catalysis. Science, 355, 2017
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5K3B
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![BU of 5k3b by Molmil](/molmil-images/mine/5k3b) | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Chloroacetate - Cocrystallized | 分子名称: | CHLORIDE ION, Fluoroacetate dehalogenase, chloroacetic acid | 著者 | Mehrabi, P, Kim, T.H, Prosser, S.R, Pai, E.F. | 登録日 | 2016-05-19 | 公開日 | 2017-02-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | The role of dimer asymmetry and protomer dynamics in enzyme catalysis. Science, 355, 2017
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5K3C
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![BU of 5k3c by Molmil](/molmil-images/mine/5k3c) | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - WT/5-Fluorotryptophan | 分子名称: | CHLORIDE ION, Fluoroacetate dehalogenase | 著者 | Mehrabi, P, Kim, T.H, Prosser, S.R, Pai, E.F. | 登録日 | 2016-05-19 | 公開日 | 2017-02-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.541 Å) | 主引用文献 | The role of dimer asymmetry and protomer dynamics in enzyme catalysis. Science, 355, 2017
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5VB2
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4US2
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![BU of 4us2 by Molmil](/molmil-images/mine/4us2) | The crystal structure of H-Ras and SOS in complex with ligands | 分子名称: | 3-[(3R)-1-ethyl-2,5-dioxopyrrolidin-3-yl]benzamide, GTPASE HRAS, SON OF SEVENLESS HOMOLOG 1 | 著者 | Winter, J.J.G, Anderson, M, Blades, K, Brassington, C, Breeze, A.L, Chresta, C, Embrey, K, Fairley, G, Faulder, P, Finlay, M.R.V, Kettle, J.G, Nowak, T, Overman, R, Patel, S.J, Perkins, P, Spadola, L, Tart, J, Tucker, J, Wrigley, G. | 登録日 | 2014-07-02 | 公開日 | 2015-03-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Small Molecule Binding Sites on the Ras:SOS Complex Can be Exploited for Inhibition of Ras Activation. J.Med.Chem., 58, 2015
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6QKU
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![BU of 6qku by Molmil](/molmil-images/mine/6qku) | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Tyr219Phe - Chloroacetate soaked 2hr | 分子名称: | CHLORIDE ION, Fluoroacetate dehalogenase, GLYCOLIC ACID, ... | 著者 | Mehrabi, P, Kim, T.H, Prosser, R.S, Pai, E.F. | 登録日 | 2019-01-30 | 公開日 | 2019-06-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.511 Å) | 主引用文献 | Substrate-Based Allosteric Regulation of a Homodimeric Enzyme. J.Am.Chem.Soc., 141, 2019
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6QKW
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![BU of 6qkw by Molmil](/molmil-images/mine/6qkw) | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Tyr219Phe - Fluoroacetate soaked 2hr | 分子名称: | CHLORIDE ION, Fluoroacetate dehalogenase, GLYCOLIC ACID, ... | 著者 | Mehrabi, P, Kim, T.H, Prosser, R.S, Pai, E.F. | 登録日 | 2019-01-30 | 公開日 | 2019-06-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.512 Å) | 主引用文献 | Substrate-Based Allosteric Regulation of a Homodimeric Enzyme. J.Am.Chem.Soc., 141, 2019
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