5W1D
 
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5W4T
 | | Crystal Structure of Fish Cadherin-23 EC1-3 | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ... | | 著者 | De-la-Torre, P, Sotomayor, M. | | 登録日 | 2017-06-12 | | 公開日 | 2018-06-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness.
Structure, 26, 2018
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5VT8
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5USA
 | | 5-Se-T2-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant | | 分子名称: | DNA (5'-D(*AP*(T5S)P*GP*TP*CP*G)-3'), MAGNESIUM ION, RNA (5'-R(*UP*CP*GP*AP*CP*A)-3'), ... | | 著者 | Fang, Z, Qin, L, Huang, Z. | | 登録日 | 2017-02-13 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate
Chemistryselect, 8, 2023
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5USE
 | | 5-Se-T4-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant | | 分子名称: | DNA (5'-D(*AP*TP*GP*(T5S)P*CP*G)-3'), MAGNESIUM ION, RNA (5'-R(*UP*CP*GP*AP*CP*A)-3'), ... | | 著者 | Fang, Z, Qin, L, Huang, Z. | | 登録日 | 2017-02-13 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate
Chemistryselect, 8, 2023
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4NEA
 | | 1.90 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) from Staphylococcus aureus in complex with NAD+ and BME-free Cys289 | | 分子名称: | Betaine aldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, POTASSIUM ION | | 著者 | Halavaty, A.S, Minasov, G, Winsor, J, Dubrovska, I, Shuvalova, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2013-10-28 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and functional analysis of betaine aldehyde dehydrogenase from Staphylococcus aureus.
Acta Crystallogr.,Sect.D, 71, 2015
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4NU9
 | | 2.30 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) from Staphylococcus aureus with BME-free Cys289 | | 分子名称: | Betaine aldehyde dehydrogenase, SODIUM ION | | 著者 | Halavaty, A.S, Minasov, G, Dubrovska, I, Stam, J, Shuvalova, L, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2013-12-03 | | 公開日 | 2013-12-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and functional analysis of betaine aldehyde dehydrogenase from Staphylococcus aureus.
Acta Crystallogr.,Sect.D, 71, 2015
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5ULU
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5WJM
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5UN2
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3VB4
 | | Crystal structure of SARS-CoV 3C-like protease with B4Z | | 分子名称: | 1,2-ETHANEDIOL, 3C-like proteinase, B4Z inhibitor, ... | | 著者 | Chuck, C.P, Wong, K.B. | | 登録日 | 2011-12-31 | | 公開日 | 2012-12-12 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Design, synthesis and crystallographic analysis of nitrile-based broad-spectrum peptidomimetic inhibitors for coronavirus 3C-like proteases
Eur.J.Med.Chem., 59C, 2012
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3VB5
 | | Crystal structure of SARS-CoV 3C-like protease with C4Z | | 分子名称: | 1,2-ETHANEDIOL, 3C-like proteinase, C4Z inhibitor | | 著者 | Chuck, C.P, Wong, K.B. | | 登録日 | 2011-12-31 | | 公開日 | 2012-12-12 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Design, synthesis and crystallographic analysis of nitrile-based broad-spectrum peptidomimetic inhibitors for coronavirus 3C-like proteases
Eur.J.Med.Chem., 59C, 2012
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3TS2
 | | Mouse Lin28A in complex with let-7g microRNA pre-element | | 分子名称: | Protein lin-28 homolog A, RNA (5'-R(*GP*GP*GP*GP*UP*CP*UP*AP*UP*GP*AP*UP*AP*CP*CP*AP*CP*CP*CP*CP*GP*GP*AP*G)-3'), ZINC ION | | 著者 | Nam, Y, Sliz, P. | | 登録日 | 2011-09-11 | | 公開日 | 2011-11-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Molecular Basis for Interaction of let-7 MicroRNAs with Lin28.
Cell(Cambridge,Mass.), 147, 2011
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5WJR
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5X39
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5X34
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3VB6
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3VB3
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5VJJ
 | | Crystal structure of the flax-rust effector AvrP | | 分子名称: | Avirulence protein AvrP123, ZINC ION | | 著者 | Zhang, X, Ericsson, D.J, Williams, S.J, Kobe, B. | | 登録日 | 2017-04-19 | | 公開日 | 2017-08-30 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | Crystal structure of the Melampsora lini effector AvrP reveals insights into a possible nuclear function and recognition by the flax disease resistance protein P.
Mol. Plant Pathol., 19, 2018
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2LA5
 | | RNA Duplex-Quadruplex Junction Complex with FMRP RGG peptide | | 分子名称: | Fragile X mental retardation 1 protein, RNA (36-MER) | | 著者 | Phan, A, Kuryavyi, V, Darnell, J, Serganov, A, Majumdar, A, Ilin, S, Darnell, R, Patel, D. | | 登録日 | 2011-03-03 | | 公開日 | 2011-06-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction.
Nat.Struct.Mol.Biol., 18, 2011
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5HU9
 | | Crystal structure of ABL1 in complex with CHMFL-074 | | 分子名称: | 1,2-ETHANEDIOL, 4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[1-(pyridin-3-ylcarbonyl)piperidin-4-yl]oxy}phenyl)-3-(trifluoromethyl)benzamide, CHLORIDE ION, ... | | 著者 | Kong, L.L, Yun, C.H. | | 登録日 | 2016-01-27 | | 公開日 | 2016-07-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.529 Å) | | 主引用文献 | Discovery and characterization of a novel potent type II native and mutant BCR-ABL inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML)
Oncotarget, 7, 2016
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2MDT
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4P9M
 | | Crystal structure of 8ANC195 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 Fab heavy chain, 8ANC195 light chain | | 著者 | Scharf, L, Bjorkman, P.J. | | 登録日 | 2014-04-04 | | 公開日 | 2014-05-21 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike.
Cell Rep, 7, 2014
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4S05
 | | Crystal structure of Klebsiella pneumoniae PmrA in complex with PmrA box DNA | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, DNA (26-MER), DNA-binding transcriptional regulator BasR, ... | | 著者 | Hsiao, C.D, Weng, T.H, Li, Y.C. | | 登録日 | 2014-12-30 | | 公開日 | 2015-11-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Structure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNA.
Nat Commun, 6, 2015
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3GCW
 | | PCSK9:EGFA(H306Y) | | 分子名称: | CALCIUM ION, Low-density lipoprotein receptor, Proprotein convertase subtilisin/kexin type 9 | | 著者 | Kwon, H.J. | | 登録日 | 2009-02-22 | | 公開日 | 2009-03-03 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Antagonism of Secreted PCSK9 Increases Low Density Lipoprotein Receptor Expression in HepG2 Cells.
J.Biol.Chem., 284, 2009
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