5UN2

Crystal Structure of Mouse Cadherin-23 EC19-21 with non-syndromic deafness (DFNB12) associated mutation R2029W

Summary for 5UN2

Entry DOI	10.2210/pdb5un2/pdb
Descriptor	Cadherin-23, CALCIUM ION, POTASSIUM ION, ... (4 entities in total)
Functional Keywords	hearing, mechanotransduction, adhesion, calcium-binding protein, cell adhesion
Biological source	Mus musculus (Mouse)
Total number of polymer chains	1
Total formula weight	37977.59
Authors	Jaiganesh, A.,Sotomayor, M. (deposition date: 2017-01-30, release date: 2018-02-07, Last modification date: 2023-10-04)
Primary citation	Jaiganesh, A.,De-la-Torre, P.,Patel, A.A.,Termine, D.J.,Velez-Cortes, F.,Chen, C.,Sotomayor, M. Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness. Structure, 26:1210-, 2018 Cited by PubMed: 30033219 DOI: 10.1016/j.str.2018.06.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.96 Å)

Structure validation