5UN2
Crystal Structure of Mouse Cadherin-23 EC19-21 with non-syndromic deafness (DFNB12) associated mutation R2029W
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cadherin-23 | polymer | 344 | 37578.8 | 1 | UniProt (Q99PF4) Pfam (PF00028) | Mus musculus (Mouse) | Otocadherin |
| 2 | B, C, D, E, F... (A) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 3 | J, K (A) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 4 | L (A) | water | water | 18.0 | 59 | Chemie (HOH) |
Sequence modifications
A: 1932 - 2266 (UniProt: Q99PF4)
| PDB | External Database | Details |
|---|---|---|
| Met 1931 | - | initiating methionine |
| Trp 2006 | Arg 2029 | engineered mutation |
| Leu 2267 | - | expression tag |
| Glu 2268 | - | expression tag |
| His 2269 | - | expression tag |
| His 2270 | - | expression tag |
| His 2271 | - | expression tag |
| His 2272 | - | expression tag |
| His 2273 | - | expression tag |
| His 2274 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37578.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 398.8 | |
| All* | Total formula weight | 37977.6 |
