2L3R
| NMR structure of UHRF1 Tandem Tudor Domains in a complex with Histone H3 peptide | 分子名称: | E3 ubiquitin-protein ligase UHRF1, Histone H3 | 著者 | Nady, N, Lemak, A, Fares, C, Gutmanas, A, Avvakumov, G, Xue, S, Arrowsmith, C, Structural Genomics Consortium (SGC) | 登録日 | 2010-09-21 | 公開日 | 2011-04-13 | 最終更新日 | 2020-02-05 | 実験手法 | SOLUTION NMR | 主引用文献 | Recognition of Multivalent Histone States Associated with Heterochromatin by UHRF1 Protein. J.Biol.Chem., 286, 2011
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4F09
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3T9B
| Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with AMPPNP at pH 5.2 | 分子名称: | Inositol Pyrophosphate Kinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Wang, H, Falck, J, Hall, T.M.T, Shears, S.B. | 登録日 | 2011-08-02 | 公開日 | 2011-12-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding. Nat.Chem.Biol., 8, 2011
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3TCL
| Crystal Structure of HIV-1 Neutralizing Antibody CH04 | 分子名称: | CH04 Heavy Chain Fab, CH04 Light Chain Fab, IMIDAZOLE | 著者 | Louder, R.K, McLellan, J.S, Pancera, M, Yang, Y, Zhang, B, Bonsignori, M, Kwong, P.D. | 登録日 | 2011-08-09 | 公開日 | 2011-11-30 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (1.906 Å) | 主引用文献 | Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature, 480, 2011
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3TGT
| Crystal structure of unliganded HIV-1 clade A/E strain 93TH057 gp120 core | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 clade A/E 93TH057 gp120 | 著者 | Kwon, Y.D, Kwong, P.D. | 登録日 | 2011-08-17 | 公開日 | 2012-04-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops. Proc.Natl.Acad.Sci.USA, 109, 2012
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7M0G
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2LWE
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4G1Q
| Crystal structure of HIV-1 reverse transcriptase (RT) in complex with Rilpivirine (TMC278, Edurant), a non-nucleoside rt-inhibiting drug | 分子名称: | 1,2-ETHANEDIOL, 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, MAGNESIUM ION, ... | 著者 | Bauman, J.D, Patel, D, Das, K, Arnold, E. | 登録日 | 2012-07-11 | 公開日 | 2013-02-06 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase. Nat Chem, 5, 2013
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4G2S
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4G31
| Crystal Structure of GSK6414 Bound to PERK (R587-R1092, delete A660-T867) at 2.28 A Resolution | 分子名称: | 1-[5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone, Eukaryotic translation initiation factor 2-alpha kinase 3, GLYCEROL | 著者 | Gampe, R.T, Axten, J.M. | 登録日 | 2012-07-13 | 公開日 | 2012-08-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK). J.Med.Chem., 55, 2012
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3T7A
| Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ADP at pH 5.2 | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Wang, H, Falck, J, Hall, T.M.T, Shears, S.B. | 登録日 | 2011-07-29 | 公開日 | 2011-12-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding. Nat.Chem.Biol., 8, 2011
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3T54
| Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ATP and Cadmium | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CADMIUM ION, Inositol Pyrophosphate Kinase | 著者 | Wang, H, Falck, J, Hall, T.M.T, Shears, S.B. | 登録日 | 2011-07-26 | 公開日 | 2011-12-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding. Nat.Chem.Biol., 8, 2011
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3T9F
| Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ADP and 1,5-(PP)2-IP4 (1,5-IP8) | 分子名称: | (1R,3S,4R,5S,6R)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl bis[trihydrogen (diphosphate)], ADENOSINE-5'-DIPHOSPHATE, CADMIUM ION, ... | 著者 | Wang, H, Falck, J, Hall, T.M.T, Shears, S.B. | 登録日 | 2011-08-02 | 公開日 | 2011-12-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding. Nat.Chem.Biol., 8, 2011
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4G9F
| Crystal Structure of C12C TCR-HLAB2705-KK10-L6M | 分子名称: | Beta-2-microglobulin, Gag protein, HLA class I histocompatibility antigen, ... | 著者 | Gras, S, Wilmann, P.G, Rossjohn, J. | 登録日 | 2012-07-23 | 公開日 | 2013-03-20 | 最終更新日 | 2020-04-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells. Immunity, 38, 2013
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2LWD
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7NO8
| Structure of the mature RSV CA lattice: Group I, pentamer-hexamer interface, class 1"6 | 分子名称: | Capsid protein p27, alternate cleaved 1 | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | 登録日 | 2021-02-25 | 公開日 | 2021-04-21 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NOM
| Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 4'Beta | 分子名称: | Capsid protein p27, alternate cleaved 1 | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | 登録日 | 2021-02-25 | 公開日 | 2021-04-21 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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4FXJ
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7NO6
| Structure of the mature RSV CA lattice: Group I, pentamer-hexamer interface, class 1 | 分子名称: | Capsid protein p27, alternate cleaved 1 | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | 登録日 | 2021-02-25 | 公開日 | 2021-04-21 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NOG
| Structure of the mature RSV CA lattice: Group III, hexamer-hexamer interface, class 4'5 | 分子名称: | Capsid protein p27, alternate cleaved 1 | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | 登録日 | 2021-02-25 | 公開日 | 2021-04-21 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NO0
| Structure of the mature RSV CA lattice: T=1 CA icosahedron | 分子名称: | Capsid protein p27, alternate cleaved 1 | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | 登録日 | 2021-02-25 | 公開日 | 2021-04-21 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NOB
| Structure of the mature RSV CA lattice: Group II, hexamer-hexamer interface, class 2'6 | 分子名称: | Capsid protein p27, alternate cleaved 1 | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | 登録日 | 2021-02-25 | 公開日 | 2021-04-21 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NON
| Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 4'Gamma | 分子名称: | Capsid protein p27, alternate cleaved 1 | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | 登録日 | 2021-02-25 | 公開日 | 2021-04-21 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NO1
| Structure of the mature RSV CA lattice: T=3 CA icosahedron | 分子名称: | Capsid protein p27, alternate cleaved 1 | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | 登録日 | 2021-02-25 | 公開日 | 2021-04-21 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NOE
| Structure of the mature RSV CA lattice: Group III, hexamer-hexamer interface, class 3'5 | 分子名称: | Capsid protein p27, alternate cleaved 1 | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | 登録日 | 2021-02-25 | 公開日 | 2021-04-21 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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