8SSJ
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4ZE9
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8SUI
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8SSY
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7BWO
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7BWE
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6QUS
| HsCKK (human CAMSAP1) decorated 13pf taxol-GDP microtubule | 分子名称: | Calmodulin-regulated spectrin-associated protein 1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Atherton, J.M, Luo, Y, Xiang, S, Yang, C, Jiang, K, Stangier, M, Vemu, A, Cook, A, Wang, S, Roll-Mecak, A, Steinmetz, M.O, Akhmanova, A, Baldus, M, Moores, C.A. | 登録日 | 2019-02-28 | 公開日 | 2019-11-27 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural determinants of microtubule minus end preference in CAMSAP CKK domains. Nat Commun, 10, 2019
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5DM7
| Crystal structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with hygromycin A | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ... | 著者 | Kaminishi, T, Schedlbauer, A, Ochoa-Lizarralde, B, Connell, S.R, Fucini, P. | 登録日 | 2015-09-08 | 公開日 | 2015-11-11 | 最終更新日 | 2015-11-25 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A. Nucleic Acids Res., 43, 2015
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5DRS
| Crystal structure of human carbonic anhydraseisozyme II with 3-[(1S)-2,3-Dihydro-1H-inden-1-ylamino]-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide, BICINE, ... | 著者 | Smirnov, A, Manakova, E, Grazulis, S. | 登録日 | 2015-09-16 | 公開日 | 2016-09-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Intrinsic Thermodynamics and Structures of 2,4- and 3,4-Substituted Fluorinated Benzenesulfonamides Binding to Carbonic Anhydrases. ChemMedChem, 12, 2017
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4ZED
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7R01
| BAZ2A bromodomain in complex with N-acetylpiperazine derivative fragment 18 | 分子名称: | 1,2-ETHANEDIOL, 1-[4-(4-ethanoylpiperazin-1-yl)phenyl]guanidine, Bromodomain adjacent to zinc finger domain protein 2A, ... | 著者 | Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. | 登録日 | 2022-02-01 | 公開日 | 2022-09-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.256 Å) | 主引用文献 | Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
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7QZT
| BAZ2A bromodomain in complex with isoquinoline derivative fragment 9 | 分子名称: | Bromodomain adjacent to zinc finger domain protein 2A, ~{N}-[(3~{S})-pyrrolidin-3-yl]isoquinoline-5-sulfonamide | 著者 | Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. | 登録日 | 2022-01-31 | 公開日 | 2022-09-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.183 Å) | 主引用文献 | Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
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7R0B
| BAZ2A bromodomain in complex with acetylpyrrole derivative compound 47 | 分子名称: | 1,2-ETHANEDIOL, 1-[4-ethyl-2-methyl-5-(2-piperazin-1-yl-1,3-thiazol-4-yl)-1~{H}-pyrrol-3-yl]ethanone, Bromodomain adjacent to zinc finger domain protein 2A, ... | 著者 | Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. | 登録日 | 2022-02-01 | 公開日 | 2022-09-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.345 Å) | 主引用文献 | Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
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5DOH
| Crystal structure of human carbonic anhydrase isozyme II with 2-[(1S)-2,3-Dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide | 分子名称: | 2-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)sulfanyl]benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... | 著者 | Smirnov, A, Manakova, E, Grazulis, S. | 登録日 | 2015-09-11 | 公開日 | 2016-09-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | Intrinsic Thermodynamics and Structures of 2,4- and 3,4-Substituted Fluorinated Benzenesulfonamides Binding to Carbonic Anhydrases. ChemMedChem, 12, 2017
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7U0R
| Crystal structure of Methanomethylophilus alvus PylRS(N166A/V168A) complexed with meta-trifluoromethyl-2-benzylmalonate and AMP-PNP | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Swenson, C.V, Roe, L.T, Fricke, R.C.B, Smaga, S.S, Gee, C.L, Schepartz, A. | 登録日 | 2022-02-18 | 公開日 | 2023-06-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Expanding the substrate scope of pyrrolysyl-transfer RNA synthetase enzymes to include non-alpha-amino acids in vitro and in vivo. Nat.Chem., 15, 2023
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6R85
| Structure of Arabidopsis thaliana GLR3.3 ligand-binding domain in complex with L-glutamate | 分子名称: | 1,2-ETHANEDIOL, GLUTAMIC ACID, Glutamate receptor 3.3,Glutamate receptor 3.3, ... | 著者 | Alfieri, A, Pederzoli, R, Costa, A. | 登録日 | 2019-03-31 | 公開日 | 2020-01-01 | 最終更新日 | 2020-01-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The structural bases for agonist diversity in anArabidopsis thalianaglutamate receptor-like channel. Proc.Natl.Acad.Sci.USA, 117, 2020
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6R8A
| Structure of Arabidopsis thaliana GLR3.3 ligand-binding domain in complex with L-methionine | 分子名称: | Glutamate receptor 3.3,Glutamate receptor 3.3, METHIONINE, SODIUM ION, ... | 著者 | Alfieri, A, Pederzoli, R, Costa, A. | 登録日 | 2019-04-01 | 公開日 | 2020-01-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The structural bases for agonist diversity in anArabidopsis thalianaglutamate receptor-like channel. Proc.Natl.Acad.Sci.USA, 117, 2020
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7ACD
| Crystal structure of the human METTL3-METTL14 complex with compound T30 (UZH1a) | 分子名称: | 4-[(4,4-dimethylpiperidin-1-yl)methyl]-2-oxidanyl-~{N}-[[(3~{R})-3-oxidanyl-1-[6-[(phenylmethyl)amino]pyrimidin-4-yl]piperidin-3-yl]methyl]benzamide, ACETATE ION, MAGNESIUM ION, ... | 著者 | Bedi, R.K, Huang, D, Caflisch, A. | 登録日 | 2020-09-10 | 公開日 | 2020-10-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | METTL3 Inhibitors for Epitranscriptomic Modulation of Cellular Processes. Chemmedchem, 16, 2021
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4K8C
| Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with ADP | 分子名称: | ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, ... | 著者 | Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2013-04-18 | 公開日 | 2013-05-01 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with ADP To be Published
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4K93
| CRYSTAL STRUCTURE OF probable sugar kinase protein from Rhizobium etli CFN 42 complexed with N-(HYDROXYMETHYL)BENZAMIDE | 分子名称: | ADENOSINE, DIMETHYL SULFOXIDE, N-(hydroxymethyl)benzamide, ... | 著者 | Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2013-04-19 | 公開日 | 2013-05-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | CRYSTAL STRUCTURE OF probable sugar kinase protein from Rhizobium etli CFN 42 complexed with N-(HYDROXYMETHYL)BENZAMIDE To be Published
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4KBE
| Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with benzoguanamine | 分子名称: | 6-phenyl-1,3,5-triazine-2,4-diamine, ADENOSINE, DIMETHYL SULFOXIDE, ... | 著者 | Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2013-04-23 | 公開日 | 2013-05-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with benzoguanamine To be Published
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4K8T
| Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with ethyl 3,4-diaminobenzoate | 分子名称: | ADENOSINE, DIMETHYL SULFOXIDE, POTASSIUM ION, ... | 著者 | Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2013-04-18 | 公開日 | 2013-05-01 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with ethyl 3,4-diaminobenzoate To be Published
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7RR7
| Multidrug efflux pump subunit AcrB | 分子名称: | DODECANE, Multidrug efflux pump subunit AcrB, PHOSPHATIDYLETHANOLAMINE | 著者 | Trinh, T.K.H, Cabezas, A, Catalano, C, Qiu, W, des Georges, A, Guo, Y. | 登録日 | 2021-08-09 | 公開日 | 2022-08-17 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Multidrug efflux pump subunit AcrB To Be Published
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7RR8
| Multidrug efflux pump subunit AcrB | 分子名称: | DODECANE, Multidrug efflux pump subunit AcrB, PHOSPHATIDYLETHANOLAMINE | 著者 | Trinh, T.K.H, Cabezas, A, Catalano, C, Qiu, W, des Georges, A, Guo, Y. | 登録日 | 2021-08-09 | 公開日 | 2022-08-17 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.51 Å) | 主引用文献 | Multidrug efflux pump subunit AcrB To Be Published
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7RR6
| Multidrug efflux pump subunit AcrB | 分子名称: | DODECANE, Multidrug efflux pump subunit AcrB, PHOSPHATIDYLETHANOLAMINE | 著者 | Trinh, T.K.H, Cabezas, A, Catalano, C, Qiu, W, des Georges, A, Guo, Y. | 登録日 | 2021-08-09 | 公開日 | 2022-08-17 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Multidrug efflux pump subunit AcrB To Be Published
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