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8E3D
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BU of 8e3d by Molmil
ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing CAST sequence (#11)
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*TP*TP*TP*GP*GP*GP*GP*AP*GP*GP*GP*GP*TP*CP*TP*TP*TP*AP*AP*CP*C)-3'), DNA (5'-D(P*GP*GP*TP*AP*AP*AP*AP*GP*AP*CP*CP*CP*CP*TP*CP*CP*CP*CP*AP*AP*AP*T)-3'), ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2022-08-17
公開日2023-02-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
8E3E
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BU of 8e3e by Molmil
ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing CAST sequence (#10)
分子名称: DNA (5'-D(*CP*TP*TP*TP*GP*GP*GP*GP*AP*GP*GP*GP*GP*TP*CP*TP*TP*TP*TP*AP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*AP*AP*AP*GP*AP*CP*CP*CP*CP*TP*CP*CP*CP*CP*AP*AP*A)-3'), ZINC ION, ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2022-08-17
公開日2023-02-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
7M8K
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BU of 7m8k by Molmil
Cryo-EM structure of Brazil (P.1) SARS-CoV-2 spike glycoprotein variant in the prefusion state (1 RBD up)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Casner, R.G, Cerutti, G, Shapiro, L, Ho, D.D.
登録日2021-03-29
公開日2021-05-05
最終更新日2021-05-26
実験手法ELECTRON MICROSCOPY
主引用文献Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization.
Cell Host Microbe, 29, 2021
8DNN
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BU of 8dnn by Molmil
Crystal structure of neutralizing antibody 80 in complex with SARS-CoV-2 receptor binding domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 80 FAB HEAVY CHAIN, 80 FAB LIGHT CHAIN, ...
著者Muthuraman, K, Kucharska, I, Ivanochko, D, Julien, J.P.
登録日2022-07-11
公開日2023-05-24
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo.
Sci Transl Med, 15, 2023
8DST
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BU of 8dst by Molmil
Cryo-EM of NBD-ffsy filaments (class 2)
分子名称: NBD-ffsy peptide
著者Wang, F, Guo, J, Xu, B, Egelman, E.H.
登録日2022-07-22
公開日2023-05-31
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cell spheroid creation by transcytotic intercellular gelation.
Nat Nanotechnol, 18, 2023
8EPN
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BU of 8epn by Molmil
Cryo-EM structure of SARS-CoV-2 Spike trimer S2D14 in the 3-RBD Down conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Williams, J.A, Harshbarger, W.
登録日2022-10-06
公開日2023-06-21
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural and computational design of a SARS-CoV-2 spike antigen with improved expression and immunogenicity.
Sci Adv, 9, 2023
8EPQ
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BU of 8epq by Molmil
Cryo-EM structure of SARS-CoV-2 Spike trimer S2D14 with two RBDs exposed
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Williams, J.A, Harshbarger, W.
登録日2022-10-06
公開日2023-06-21
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural and computational design of a SARS-CoV-2 spike antigen with improved expression and immunogenicity.
Sci Adv, 9, 2023
8EPP
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BU of 8epp by Molmil
Cryo-EM structure of SARS-CoV-2 Spike trimer S2D14 with two RBDs in the open conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Williams, J.A, Harshbarger, W.
登録日2022-10-06
公開日2023-06-21
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural and computational design of a SARS-CoV-2 spike antigen with improved expression and immunogenicity.
Sci Adv, 9, 2023
7MXP
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BU of 7mxp by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody LP5 Fab in complex with SARS-CoV-2 S2P spike
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)][beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Reddem, E.R, Casner, R.G, Shapiro, L.
登録日2021-05-19
公開日2022-05-25
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (4.46 Å)
主引用文献Antibody screening at reduced pH enables preferential selection of potently neutralizing antibodies targeting SARS-CoV-2.
Aiche J, 67, 2021
2NNQ
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BU of 2nnq by Molmil
Crystal structure of human adipocyte fatty acid binding protein in complex with ((2'-(5-ethyl-3,4-diphenyl-1H-pyrazol-1-yl)-3-biphenylyl)oxy)acetic acid
分子名称: ((2'-(5-ETHYL-3,4-DIPHENYL-1H-PYRAZOL-1-YL)-3-BIPHENYLYL)OXY)ACETIC ACID, Fatty acid-binding protein, adipocyte, ...
著者Jacobson, B.L.
登録日2006-10-24
公開日2007-06-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP).
Bioorg.Med.Chem.Lett., 17, 2007
7N5U
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BU of 7n5u by Molmil
ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing GGACCC (Oligo 21)
分子名称: DNA Strain II, DNA Strand I, ZINC ION, ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2021-06-06
公開日2022-06-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
7N5W
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BU of 7n5w by Molmil
ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing GGACCC (Oligo 23)
分子名称: 1,2-ETHANEDIOL, DNA Strand I, DNA Strand II, ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2021-06-06
公開日2022-06-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
7N5V
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BU of 7n5v by Molmil
ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing GGACCC (Oligo 20)
分子名称: DNA Strand I, DNA Strand II, ZINC ION, ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2021-06-06
公開日2022-06-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
6KPO
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BU of 6kpo by Molmil
Crystal Structure of endo-beta-N-acetylglucosaminidase from Cordyceps militaris D154N/E156Q mutant in complex with fucosyl-N-acetylglucosamine-Asn
分子名称: ASPARAGINE, Chitinase, DI(HYDROXYETHYL)ETHER, ...
著者Seki, H, Arakawa, T, Yamada, C, Takegawa, K, Fushinobu, S.
登録日2019-08-15
公開日2019-10-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural basis for the specific cleavage of core-fucosylatedN-glycans by endo-beta-N-acetylglucosaminidase from the fungusCordyceps militaris.
J.Biol.Chem., 294, 2019
6KPN
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BU of 6kpn by Molmil
Crystal Structure of endo-beta-N-acetylglucosaminidase from Cordyceps militaris D154N/E156Q mutant in complex with fucosyl-N-acetylglucosamine
分子名称: Chitinase, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Seki, H, Arakawa, T, Yamada, C, Takegawa, K, Fushinobu, S.
登録日2019-08-15
公開日2019-10-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for the specific cleavage of core-fucosylatedN-glycans by endo-beta-N-acetylglucosaminidase from the fungusCordyceps militaris.
J.Biol.Chem., 294, 2019
8I8C
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BU of 8i8c by Molmil
Plug structure of the Autographa californica multiple nucleopolyhedrovirus (AcMNPV)
分子名称: Occlusion-derived virus envelope/capsid protein, P40
著者Jia, X, Gao, Y, Zhang, Q.
登録日2023-02-03
公開日2023-12-13
実験手法ELECTRON MICROSCOPY (4.93 Å)
主引用文献Architecture of the baculovirus nucleocapsid revealed by cryo-EM.
Nat Commun, 14, 2023
8I8B
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BU of 8i8b by Molmil
Outer shell and inner layer structures of Autographa californica multiple nucleopolyhedrovirus (AcMNPV)
分子名称: 38K, AcOrf-109 peptide, Early 49 Daa protein, ...
著者Jia, X, Gao, Y, Zhang, Q.
登録日2023-02-03
公開日2023-12-13
実験手法ELECTRON MICROSCOPY (4.31 Å)
主引用文献Architecture of the baculovirus nucleocapsid revealed by cryo-EM.
Nat Commun, 14, 2023
6K3B
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BU of 6k3b by Molmil
Crystal structure of Lpg2147-Lpg2149 complex
分子名称: Lpg2147, Uncharacterized protein
著者Mu, Y, Wang, Y, Han, Y, Li, D, Feng, Y.
登録日2019-05-17
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.974 Å)
主引用文献Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC.
Nat Commun, 11, 2020
5YVE
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BU of 5yve by Molmil
Crystal structure of human P2X3 receptor in complex with the AF-219 negative allosteric modulator
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[2,4-bis(azanyl)pyrimidin-5-yl]oxy-2-methoxy-4-propan-2-yl-benzenesulfonamide, MAGNESIUM ION, ...
著者Wang, Y, Hattori, M.
登録日2017-11-25
公開日2018-04-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Druggable negative allosteric site of P2X3 receptors.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6KFP
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BU of 6kfp by Molmil
Crystal structure of MavC ternary complex
分子名称: MavC, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 N
著者Mu, Y, Wang, Y, Han, Y, Li, D, Feng, Y.
登録日2019-07-08
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC.
Nat Commun, 11, 2020
8I8A
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BU of 8i8a by Molmil
Cryo-EM structure of the major capsid protein VP39 of Autographa californica multiple nucleopolyhedrovirus (AcMNPV)
分子名称: Major viral capsid protein
著者Jia, X, Zhang, Q.
登録日2023-02-03
公開日2023-12-13
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Architecture of the baculovirus nucleocapsid revealed by cryo-EM.
Nat Commun, 14, 2023
5XWX
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BU of 5xwx by Molmil
Crystal structure of the four N-terminal immunoglogulin domains of Sidekick-1 protein
分子名称: Protein sidekick-1
著者Tang, H, Dong, Y, He, Y.
登録日2017-06-30
公開日2018-08-29
最終更新日2018-09-26
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Architecture of cell-cell adhesion mediated by sidekicks.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5XX0
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BU of 5xx0 by Molmil
Crystal structure of the four N-terminal immunoglogulin domains of Sidekick-2 protein
分子名称: Protein sidekick-2
著者Dong, Y, Tang, H, He, Y.
登録日2017-06-30
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Architecture of cell-cell adhesion mediated by sidekicks.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8JFI
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BU of 8jfi by Molmil
Crystal structure of 3-oxoacyl-ACP reductase FabG in complex with NADP+ and 3-keto-hexanoyl-ACP from Helicobacter pylori
分子名称: 3-oxoacyl-[acyl-carrier-protein] reductase, Acyl carrier protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Zhou, J.S, Zhang, L.
登録日2023-05-18
公開日2023-11-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献The Molecular Basis of Catalysis by SDR Family Members Ketoacyl-ACP Reductase FabG and Enoyl-ACP Reductase FabI in Type-II Fatty Acid Biosynthesis.
Angew.Chem.Int.Ed.Engl., 62, 2023
8JFA
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BU of 8jfa by Molmil
Crystal structure of 3-oxoacyl-ACP reductase FabG in complex with NADPH from Helicobacter pylori
分子名称: 3-oxoacyl-[acyl-carrier-protein] reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhou, J.S, Zhang, L.
登録日2023-05-17
公開日2023-11-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The Molecular Basis of Catalysis by SDR Family Members Ketoacyl-ACP Reductase FabG and Enoyl-ACP Reductase FabI in Type-II Fatty Acid Biosynthesis.
Angew.Chem.Int.Ed.Engl., 62, 2023

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