3KUN
 
 | | X-ray structure of the metcyano form of dehaloperoxidase from amphitrite ornata: evidence for photoreductive lysis of iron-cyanide bond | | 分子名称: | CYANIDE ION, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Serrano, V.S, Chen, Z, Gaff, J.F, Rose, R, Franzen, S. | | 登録日 | 2009-11-27 | | 公開日 | 2010-06-30 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | | 主引用文献 | X-ray structure of the metcyano form of dehaloperoxidase from Amphitrite ornata: evidence for photoreductive dissociation of the iron-cyanide bond.
Acta Crystallogr.,Sect.D, 66, 2010
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3EIQ
 | | Crystal structure of Pdcd4-eIF4A | | 分子名称: | Eukaryotic initiation factor 4A-I, Programmed cell death protein 4 | | 著者 | Loh, P.G, Cheng, Z, Song, H. | | 登録日 | 2008-09-17 | | 公開日 | 2009-02-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis for translational inhibition by the tumour suppressor Pdcd4
Embo J., 28, 2009
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5TO3
 | | Crystal structure of thrombin mutant W215A/E217A fused to EGF456 of thrombomodulin via a 31-residue linker and bound to PPACK | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... | | 著者 | Barranco-Medina, S, Murphy, M, Pelc, L, Chen, Z, Di Cera, E, Pozzi, N. | | 登録日 | 2016-10-16 | | 公開日 | 2017-03-29 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Rational Design of Protein C Activators.
Sci Rep, 7, 2017
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5TVM
 | | Crystal structure of Trypanosoma brucei AdoMetDC/prozyme heterodimer | | 分子名称: | 1,4-DIAMINOBUTANE, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, S-adenosylmethionine decarboxylase alpha chain, ... | | 著者 | Volkov, O.A, Chen, Z, Tomchick, D.R, Phillips, M.A. | | 登録日 | 2016-11-09 | | 公開日 | 2017-01-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.408 Å) | | 主引用文献 | Relief of autoinhibition by conformational switch explains enzyme activation by a catalytically dead paralog.
Elife, 5, 2016
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5TVF
 | | Crystal structure of Trypanosoma brucei AdoMetDC/prozyme heterodimer in complex with inhibitor CGP 40215 | | 分子名称: | 1,4-DIAMINOBUTANE, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-[C-[N'-(3-CARBAMIMIDOYL-BENZYLIDENIUM)-HYDRAZINO]-[[AMINOMETHYLIDENE]AMINIUM]-IMINOMETHYL]-BENZAMIDINIUM, ... | | 著者 | Phillips, M.A, Volkov, O.A, Chen, Z, Tomchick, D.R. | | 登録日 | 2016-11-08 | | 公開日 | 2017-01-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Relief of autoinhibition by conformational switch explains enzyme activation by a catalytically dead paralog.
Elife, 5, 2016
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5TVO
 | | Crystal structure of Trypanosoma brucei AdoMetDC-delta26 monomer | | 分子名称: | PYRUVIC ACID, S-adenosylmethionine decarboxylase proenzyme, SODIUM ION | | 著者 | Volkov, O.A, Ariagno, C, Chen, Z, Tomchick, D.R, Phillips, M.A. | | 登録日 | 2016-11-09 | | 公開日 | 2016-12-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.481 Å) | | 主引用文献 | Relief of autoinhibition by conformational switch explains enzyme activation by a catalytically dead paralog.
Elife, 5, 2016
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5T0L
 | | Crystal structure of Toxoplasma gondii TS-DHFR complexed with NADPH, dUMP, PDDF and 5-(4-(3,4-dichlorophenyl)piperazin-1-yl)pyrimidine-2,4-diamine (TRC-15) | | 分子名称: | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-[4-(3,4-dichlorophenyl)piperazin-1-yl]pyrimidine-2,4-diamine, ... | | 著者 | Thomas, S.B, Chen, Z, Lu, H, Li, Y. | | 登録日 | 2016-08-16 | | 公開日 | 2016-09-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | | 主引用文献 | Discovery of Potent and Selective Leads against Toxoplasma gondii Dihydrofolate Reductase via Structure-Based Design.
ACS Med Chem Lett, 7, 2016
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5TF2
 | | CRYSTAL STRUCTURE OF THE WD40 DOMAIN OF THE HUMAN PROLACTIN REGULATORY ELEMENT-BINDING PROTEIN | | 分子名称: | Prolactin regulatory element-binding protein, UNKNOWN ATOM OR ION | | 著者 | Walker, J.R, Zhang, Q, Dong, A, Wernimont, A, Li, Y, He, H, Tempel, W, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Chen, Z, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2016-09-23 | | 公開日 | 2016-11-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | CRYSTAL STRUCTURE OF THE WD40 DOMAIN OF THE HUMAN PROLACTIN REGULATORY ELEMENT-BINDING PROTEIN (CASP target)
To be published
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7EXM
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7EV8
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7EB2
 | | Cryo-EM structure of human GABA(B) receptor-Gi protein complex | | 分子名称: | (3S)-5,7-ditert-butyl-3-oxidanyl-3-(trifluoromethyl)-1-benzofuran-2-one, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, ... | | 著者 | Shen, C, Mao, C, Xu, C, Jin, N, Zhang, H, Shen, D, Shen, Q, Wang, X, Hou, T, Rondard, P, Chen, Z, Pin, J, Zhang, Y, Liu, J. | | 登録日 | 2021-03-08 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-07-07 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural basis of GABA B receptor-G i protein coupling.
Nature, 594, 2021
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7EE5
 | | Crystal structure of Neu5Gc bound PltC | | 分子名称: | N-glycolyl-alpha-neuraminic acid, N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, Subtilase cytotoxin subunit B-like protein, ... | | 著者 | Liu, X.Y, Chen, Z, Gao, X. | | 登録日 | 2021-03-17 | | 公開日 | 2021-12-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | | 主引用文献 | Molecular Insights into the Assembly and Functional Diversification of Typhoid Toxin.
Mbio, 13, 2022
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7EE4
 | | Crystal structure of Neu5Ac bound PltC | | 分子名称: | N-acetyl-alpha-neuraminic acid, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, ... | | 著者 | Liu, X.Y, Chen, Z, Gao, X. | | 登録日 | 2021-03-17 | | 公開日 | 2021-12-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Molecular Insights into the Assembly and Functional Diversification of Typhoid Toxin.
Mbio, 13, 2022
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7EE6
 | | Crystal structure of PltC toxin | | 分子名称: | ACETONE, CITRATE ANION, Cytolethal distending toxin subunit B family protein, ... | | 著者 | Liu, X.Y, Chen, Z, Gao, X. | | 登録日 | 2021-03-17 | | 公開日 | 2021-12-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Molecular Insights into the Assembly and Functional Diversification of Typhoid Toxin.
Mbio, 13, 2022
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7EE3
 | | Crystal structure of PltC | | 分子名称: | Subtilase cytotoxin subunit B-like protein, TETRAETHYLENE GLYCOL | | 著者 | Liu, X.Y, Chen, Z, Gao, X. | | 登録日 | 2021-03-17 | | 公開日 | 2021-12-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | Molecular Insights into the Assembly and Functional Diversification of Typhoid Toxin.
Mbio, 13, 2022
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6L5M
 | | Crystal structure of human DEAD-box RNA helicase DDX21 in complex with AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, Nucleolar RNA helicase 2 | | 著者 | Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X. | | 登録日 | 2019-10-24 | | 公開日 | 2020-06-17 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Adv Sci, 7, 2020
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6L5L
 | | Crystal structure of human DEAD-box RNA helicase DDX21 at apo state | | 分子名称: | MAGNESIUM ION, Nucleolar RNA helicase 2 | | 著者 | Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X. | | 登録日 | 2019-10-24 | | 公開日 | 2020-06-17 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Adv Sci, 7, 2020
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6L5N
 | | Crystal structure of human DEAD-box RNA helicase DDX21 at post-unwound state | | 分子名称: | MAGNESIUM ION, Nucleolar RNA helicase 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X. | | 登録日 | 2019-10-24 | | 公開日 | 2020-06-17 | | 最終更新日 | 2020-08-12 | | 実験手法 | X-RAY DIFFRACTION (2.242 Å) | | 主引用文献 | Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Adv Sci, 7, 2020
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6L5O
 | | Crystal structure of human DEAD-box RNA helicase DDX21 at post-hydrolysis state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X. | | 登録日 | 2019-10-24 | | 公開日 | 2020-06-17 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Adv Sci, 7, 2020
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8YLC
 | | The crystal structure of PDE4D with Amentoflavone | | 分子名称: | 3',5'-cyclic-AMP phosphodiesterase 4D, 8-[5-[5,7-bis(oxidanyl)-4-oxidanylidene-chromen-2-yl]-2-oxidanyl-phenyl]-2-(4-hydroxyphenyl)-5,7-bis(oxidanyl)chromen-4-one, MAGNESIUM ION, ... | | 著者 | Huang, Y.-Y, Luo, H.-B. | | 登録日 | 2024-03-06 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (2.30003715 Å) | | 主引用文献 | Discovery of amentoflavone as a natural PDE4 inhibitor with anti-fibrotic effects
Chin.Chem.Lett., 2024
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8GU4
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8GU5
 | | Wild type poly(ethylene terephthalate) hydrolase | | 分子名称: | Poly(ethylene terephthalate) hydrolase | | 著者 | Xiao, Y.J, Wang, Z.F. | | 登録日 | 2022-09-09 | | 公開日 | 2022-11-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Biodegradation of highly crystallized poly(ethylene terephthalate) through cell surface codisplay of bacterial PETase and hydrophobin.
Nat Commun, 13, 2022
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7CHI
 | | crystal structure of pco5 | | 分子名称: | FE (III) ION, Plant cysteine oxidase 5 | | 著者 | Guo, Q, Xu, C, Liao, S. | | 登録日 | 2020-07-05 | | 公開日 | 2020-11-25 | | 最終更新日 | 2021-03-31 | | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | | 主引用文献 | Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana.
J.Struct.Biol., 213, 2021
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1BMV
 | | PROTEIN-RNA INTERACTIONS IN AN ICOSAHEDRAL VIRUS AT 3.0 ANGSTROMS RESOLUTION | | 分子名称: | PROTEIN (ICOSAHEDRAL VIRUS - A DOMAIN), PROTEIN (ICOSAHEDRAL VIRUS - B AND C DOMAIN), RNA (5'-R(*GP*GP*UP*CP*AP*AP*AP*AP*UP*GP*C)-3') | | 著者 | Chen, Z, Stauffacher, C, Li, Y, Schmidt, T, Bomu, W, Kamer, G, Shanks, M, Lomonossoff, G, Johnson, J.E. | | 登録日 | 1989-10-09 | | 公開日 | 1989-10-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Protein-RNA interactions in an icosahedral virus at 3.0 A resolution.
Science, 245, 1989
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7U9O
 | | SARS-CoV-2 spike trimer RBD in complex with Fab NE12 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NE12 Fab heavy chain, NE12 Fab light chain, ... | | 著者 | Tsybovsky, Y, Kwong, P.D, Farci, P. | | 登録日 | 2022-03-11 | | 公開日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants.
Cell Rep, 41, 2022
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