5TVO

Crystal structure of Trypanosoma brucei AdoMetDC-delta26 monomer

Summary for 5TVO

• Entry DOI: 10.2210/pdb5tvo/pdb
• Related: 5TVF 5TVM
• Descriptor: S-adenosylmethionine decarboxylase proenzyme, PYRUVIC ACID, SODIUM ION, ... (5 entities in total)
• Functional Keywords: autoinhibition, cis-proline, lyase
• Biological source: Trypanosoma brucei brucei (strain 927/4 GUTat10.1); More
• Total number of polymer chains: 2
• Total formula weight: 38865.65

Authors

Volkov, O.A.,Ariagno, C.,Chen, Z.,Tomchick, D.R.,Phillips, M.A. (deposition date: 2016-11-09, release date: 2016-12-28, Last modification date: 2024-03-13)

• Primary citation: Volkov, O.A.,Kinch, L.N.,Ariagno, C.,Deng, X.,Zhong, S.,Grishin, N.V.,Tomchick, D.R.,Chen, Z.,Phillips, M.A.; Relief of autoinhibition by conformational switch explains enzyme activation by a catalytically dead paralog.; Elife, 5:-, 2016; PubMed: 27977001; DOI: 10.7554/eLife.20198

Experimental method

X-RAY DIFFRACTION (1.481 Å)