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6BNH
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BU of 6bnh by Molmil
Solution NMR structures of BRD4 ET domain with JMJD6 peptide
分子名称: Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, Bromodomain-containing protein 4
著者Konuma, T, Yu, D, Zhao, C, Ju, Y, Sharma, R, Ren, C, Zhang, Q, Zhou, M.-M, Zeng, L.
登録日2017-11-16
公開日2017-12-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4.
Sci Rep, 7, 2017
3QB8
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BU of 3qb8 by Molmil
Paramecium Chlorella Bursaria Virus1 Putative ORF A654L is a Polyamine Acetyltransferase
分子名称: A654L protein, COENZYME A, IMIDAZOLE
著者Charlop-Powers, Z, Zhou, M.-M, Jakoncic, J, Gurnon, J, Van Etten, J.
登録日2011-01-12
公開日2012-01-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Paramecium bursaria chlorella virus 1 encodes a polyamine acetyltransferase.
J. Biol. Chem., 287, 2012
2AQF
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BU of 2aqf by Molmil
Structural and functional analysis of ADA2 alpha swirm domain
分子名称: transcriptional adaptor 2, Ada2 alpha
著者Qian, C, Zhang, Q, Zhou, M.-M, Zeng, L.
登録日2005-08-17
公開日2006-01-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and chromosomal DNA binding of the SWIRM domain.
Nat.Struct.Mol.Biol., 12, 2005
5U5S
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BU of 5u5s by Molmil
Solution structures of Brd2 second bromodomain in complex with stat3 peptide
分子名称: Bromodomain-containing protein 2, Stat3 peptide
著者Zeng, L, Zhou, M.-M.
登録日2016-12-07
公開日2017-03-22
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation.
Mol. Cell, 65, 2017
1HZM
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BU of 1hzm by Molmil
STRUCTURE OF ERK2 BINDING DOMAIN OF MAPK PHOSPHATASE MKP-3: STRUCTURAL INSIGHTS INTO MKP-3 ACTIVATION BY ERK2
分子名称: DUAL SPECIFICITY PROTEIN PHOSPHATASE 6
著者Farooq, A, Zhou, M.-M.
登録日2001-01-25
公開日2002-01-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of ERK2 binding domain of MAPK phosphatase MKP-3: structural insights into MKP-3 activation by ERK2.
Mol.Cell, 7, 2001
1JSP
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BU of 1jsp by Molmil
NMR Structure of CBP Bromodomain in complex with p53 peptide
分子名称: CREB-BINDING PROTEIN, tumor protein p53
著者He, Y, Mujtaba, S, Zeng, L, Yan, S, Zhou, M.-M.
登録日2001-08-17
公開日2002-08-17
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation.
Mol.Cell, 13, 2004
8I60
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BU of 8i60 by Molmil
Crystal structure of GAS41 YEATS domain in complex with histone H3K27cr
分子名称: ALA-ARG-KCR-SER-ALA-PRO, GLYCEROL, SULFATE ION, ...
著者Konuma, T, Zhou, M.-M.
登録日2023-01-26
公開日2023-07-26
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin.
Mol.Cell, 83, 2023
4QB3
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BU of 4qb3 by Molmil
Crystal structure of the first bromodomain of human BRD4 in complex with Olinone
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, N-[4-(1-oxo-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)butyl]acetamide
著者Plotnikov, A.N, Joshua, J, Zhou, M.-M.
登録日2014-05-06
公開日2015-04-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (0.94 Å)
主引用文献Selective chemical modulation of gene transcription favors oligodendrocyte lineage progression.
Chem.Biol., 21, 2014
5Z9C
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BU of 5z9c by Molmil
Solution NMR structures of BRD4 first bromodomain with small compound MMQO
分子名称: 8-methoxy-6-methylquinolin-4(1H)-one, Bromodomain-containing protein 4
著者Zeng, L, Zhou, M.-M.
登録日2018-02-02
公開日2018-02-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A New Quinoline BRD4 Inhibitor Targets a Distinct Latent HIV-1 Reservoir for Reactivation from Other "Shock" Drugs.
J. Virol., 92, 2018
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