8UEO
| In-situ complex I (Active-Apo) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... | 著者 | Zheng, W, Zhu, J, Zhang, K. | 登録日 | 2023-10-02 | 公開日 | 2024-06-19 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | High-resolution in situ structures of mammalian respiratory supercomplexes. Nature, 631, 2024
|
|
8UGG
| In-situ complex III, state IV | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... | 著者 | Zheng, W, Zhang, K, Zhu, J. | 登録日 | 2023-10-05 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | High-resolution in situ structures of mammalian respiratory supercomplexes. Nature, 631, 2024
|
|
8UEW
| In-situ complex I, Deactive class05 | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | 著者 | Zheng, W, Zhu, J, Zhang, K. | 登録日 | 2023-10-02 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | High-resolution in situ structures of mammalian respiratory supercomplexes. Nature, 631, 2024
|
|
8UGP
| In-situ structure of typeA supercomplex in respiratory chain ( local refined map focused on CI iron-sulfur cluster regions ) | 分子名称: | IRON/SULFUR CLUSTER, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6, ... | 著者 | Zheng, W, Zhang, K, Zhu, J. | 登録日 | 2023-10-05 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2 Å) | 主引用文献 | High-resolution in situ structures of mammalian respiratory supercomplexes. Nature, 631, 2024
|
|
8UES
| In-situ complex I, Deactive class01 | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | 著者 | Zheng, W, Zhu, J, Zhang, K. | 登録日 | 2023-10-02 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | High-resolution in situ structures of mammalian respiratory supercomplexes. Nature, 631, 2024
|
|
8UER
| In-situ complex I with Q10 (State-gamma) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... | 著者 | Zheng, W, Zhu, J, Zhang, K. | 登録日 | 2023-10-02 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | High-resolution in situ structures of mammalian respiratory supercomplexes. Nature, 631, 2024
|
|
8UGJ
| In-situ structure of typeB supercomplex in respiratory chain (composite) | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | 著者 | Zheng, W, Zhang, K, Zhu, J. | 登録日 | 2023-10-05 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | High-resolution in situ structures of mammalian respiratory supercomplexes. Nature, 631, 2024
|
|
8UGK
| High resolution in-situ structure of complex III in respiratory supercomplex (composite) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... | 著者 | Zheng, W, Zhu, J, Zhang, K. | 登録日 | 2023-10-05 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | 主引用文献 | High-resolution in situ structures of mammalian respiratory supercomplexes. Nature, 631, 2024
|
|
6NRV
| |
7EHY
| BRD4-BD1 in complex with LT-448-138 | 分子名称: | 1-[2,4-dimethyl-5-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4 | 著者 | Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y. | 登録日 | 2021-03-30 | 公開日 | 2022-03-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | BRD4-BD1 in complex with LT-642-602 To Be Published
|
|
7EHW
| BRD4-BD1 in complex with LT-642-602 | 分子名称: | 1-[4-ethyl-2-methyl-5-(6-morpholin-4-yl-1H-benzimidazol-2-yl)-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4 | 著者 | Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y. | 登録日 | 2021-03-30 | 公開日 | 2022-03-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | BRD4-BD1 in complex with LT-642-602 To Be Published
|
|
7EIG
| BRD4-BD1 in complex with LT-730-903 | 分子名称: | 1-[5-(5-azanyl-1H-benzimidazol-2-yl)-2-methyl-4-phenyl-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4 | 著者 | Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y. | 登録日 | 2021-03-31 | 公開日 | 2022-04-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | BRD4-BD1 in complex with LT-730-903 To Be Published
|
|
7EIK
| RD4-BD1 in complex with LT-872-297 | 分子名称: | 1-[2-methyl-5-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-4-(1-methylpyrazol-4-yl)-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4 | 著者 | Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y. | 登録日 | 2021-03-31 | 公開日 | 2022-04-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | RD4-BD1 in complex with LT-872-297 To Be Published
|
|
5W5F
| Cryo-EM structure of the T4 tail tube | 分子名称: | Tail tube protein gp19 | 著者 | Zheng, W, Wang, F, Taylor, N.M, Guerrero-Ferreira, R.C, Leiman, P.G, Egelman, E.H. | 登録日 | 2017-06-15 | 公開日 | 2017-08-16 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Refined Cryo-EM Structure of the T4 Tail Tube: Exploring the Lowest Dose Limit. Structure, 25, 2017
|
|
7DMP
| Mouse radial spoke complex | 分子名称: | Radial spoke head 1 homolog, Radial spoke head protein 4 homolog A, Radial spoke head protein 9 homolog | 著者 | Zheng, W, Cong, Y. | 登録日 | 2020-12-05 | 公開日 | 2021-07-21 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Distinct architecture and composition of mouse axonemal radial spoke head revealed by cryo-EM Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
4FMU
| Crystal structure of Methyltransferase domain of human SET domain-containing protein 2 Compound: Pr-SNF | 分子名称: | (2S,5S)-2-amino-6-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-5-(propylamino)hexanoic acid, Histone-lysine N-methyltransferase SETD2, UNKNOWN ATOM OR ION, ... | 著者 | Dong, A, Zeng, H, Ibanez, G, Zheng, W, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Luo, M, Wu, H, Structural Genomics Consortium (SGC) | 登録日 | 2012-06-18 | 公開日 | 2012-09-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Sinefungin Derivatives as Inhibitors and Structure Probes of Protein Lysine Methyltransferase SETD2. J.Am.Chem.Soc., 134, 2012
|
|
6C53
| Cryo-EM structure of the Type 1 pilus rod | 分子名称: | Type-1 fimbrial protein, A chain | 著者 | Zheng, W, Wang, F, Luna-Rico, A, Francetic, O, Hultgren, S.J, Egelman, E.H. | 登録日 | 2018-01-13 | 公開日 | 2018-01-31 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions. Elife, 7, 2018
|
|
6OIF
| Cryo-EM structure of human TorsinA filament | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Torsin-1A | 著者 | Zheng, W, Demircioglu, F.E, Schwartz, T.U, Egelman, E.H. | 登録日 | 2019-04-09 | 公開日 | 2019-07-24 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | The AAA + ATPase TorsinA polymerizes into hollow helical tubes with 8.5 subunits per turn. Nat Commun, 10, 2019
|
|
6VEC
| Cryo-EM structure of F-actin/Plastin2-ABD2 complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Zheng, W, Kudryashov, D.S, Egelman, E.H. | 登録日 | 2019-12-31 | 公開日 | 2020-12-09 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Osteogenesis imperfecta mutations in plastin 3 lead to impaired calcium regulation of actin bundling. Bone Res, 8, 2020
|
|
3GCB
| GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A/DELTAK454 | 分子名称: | GAL6, GLYCEROL, SULFATE ION | 著者 | Joshua-Tor, L, Zheng, W, Johnston, S.A. | 登録日 | 1998-02-27 | 公開日 | 1998-10-21 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase. Cell(Cambridge,Mass.), 93, 1998
|
|
8TJ2
| |
7K3R
| |
6MKS
| Cryo-EM structure of NLRC4-CARD filament | 分子名称: | Chimera protein of NLR family CARD domain-containing protein 4 and EGFP | 著者 | Zheng, W, Matyszewski, M, Sohn, J, Egelman, E.H. | 登録日 | 2018-09-26 | 公開日 | 2018-11-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structure of the NLRC4CARDfilament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly. J. Biol. Chem., 293, 2018
|
|
7EIL
| BRD4-BD1 in complex with LT-909-110 | 分子名称: | Bromodomain-containing protein 4, N-[4-[4-ethanoyl-5-methyl-2-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-pyrrol-3-yl]phenyl]ethanamide | 著者 | Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y. | 登録日 | 2021-03-31 | 公開日 | 2022-04-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of 1-(5-(1H-benzo[d]imidazole-2-yl)-2,4-dimethyl-1H-pyrrol-3-yl)ethan-1-one derivatives as novel and potent bromodomain and extra-terminal (BET) inhibitors with anticancer efficacy Eur.J.Med.Chem., 227, 2022
|
|
1A6R
| GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A | 分子名称: | GAL6, SULFATE ION | 著者 | Joshua-Tor, L, Zheng, W, Johnston, S.A. | 登録日 | 1998-02-27 | 公開日 | 1998-10-21 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase. Cell(Cambridge,Mass.), 93, 1998
|
|